Advanced Science, EarlyView.Arginine deficiency accelerates androgenetic alopecia. Serum metabolome shows reduced circulating arginine, while local metabolic disruption depletes follicular reserves, triggering reactive oxygen species (ROS) accumulation and mTOR suppression that induce hair miniaturization.
Shixin Duan +19 more
wiley +1 more source
Synthesis of ∈-aspartyl-lysines and of isohexylamides of aspartic acid [PDF]
, 1958 D. L. Swallow +2 more
openalex +1 more source
Advanced Science, EarlyView.Draper is evolutionarily conserved across most insect species. Loss of Draper inhibits autophagy activation, delaying middle silk gland degradation in the silkworm during metamorphosis. Draper interacts with autophagy ‐ related protein 3 (ATG3) to orchestrate autophagosome formation—a process essential for silk gland degradation during the larval‐pupal
Shiyu Zou +9 more
wiley +1 more source
Decarboxylation-Driven Double Annulations: Innovative Multi-Component Reaction Pathways
MoleculesA concerted five-component reaction strategy has been developed, featuring double [3+2] cycloadditions utilizing aspartic acid. This approach provides valuable insights into mechanistic pathways, allowing for the distinction between concerted and ...
Desheng Zhan +4 more
doaj +1 more source
Alleviation of Seawater Stress on Tomato by Foliar Application of Aspartic Acid and Glutathione [PDF]
Journal of Stress Physiology & Biochemistry, 2013 A pot experiment was carried out in the botanical garden of Faculty of Education, Ain Shams University, with the aim of studying the effect of salinity levels (4, 8 and 16% of diluted seawater) and foliar application of aspartic acid and/or glutathione ...
Samia Ageeb Akladious +1 more
doaj
Studies in Plant Metabolism. VI. Effect of 2,4-D on the Metabolism of Aspartic Acid and Glutamic Acid in the Bean Plant. [PDF]
, 1956 Thomas Jefferson Akers, S. C. Fang
openalex +1 more source
, 1974 The process and apparatus for qualitative and quantitative analysis of the amino acid content of a biological sample are presented. The sample is deposited on a cation exchange resin and then is washed with suitable solvents.
Graff, J., Winitz, M.
core +1 more source
Regulatory effects of blood constituents on the function and metabolism of the cat brain in perfusion ezperiments. Brain perfusion with artificial blood containing low molecular dextran and amino acids [PDF]
, 1967 As a link in a series of studies on the effects of blood constituents on the brain function by means of brain perfusion, we used four kinds of artificial blood; namely, the blood containing a low molecular dextran, one containing glutamic acid, one ...
Edamatsu, Kazuyasu +5 more
core +1 more source
Src Reduces Neutrophil Extracellular Traps Generation and Resolves Acute Organ Damage
Advanced Science, EarlyView.Src reduces neutrophil extracellular traps (NETs) generation and resolves acute organ damage. Src directly activates RAF1 by regulating phosphorylation at the Ser 621 site and mediates the RAF/MEK/ERK pathway, thereby affecting the intracellular ROS production. Alternatively, Src activates the RAF1/MEK/ERK pathway by mediating PKC phosphorylation.
Guotao Lu +18 more
wiley +1 more source
P-aminobenzoic acid promotes retinal regeneration through activation of Ascl1a in zebrafish
Neural Regeneration ResearchThe retina of zebrafish can regenerate completely after injury. Multiple studies have demonstrated that metabolic alterations occur during retinal damage; however to date no study has identified a link between metabolites and retinal regeneration of ...
Meihui He +5 more
doaj +1 more source