Results 31 to 40 of about 68,617 (151)

Microbial Interventions in Processing of Plant Based Proteins: Unlocking Extraction Dynamics and Functionality for Human Health

Food Bioengineering, EarlyView.
Fermentation enhances nutritional & techno‐functional properties of plant protein. Three distinct stages of fermentation impact on different aspects of plant protein. Fermentation induces flavors modulation through new organic compounds formation. Plant protein fermentation improves their utility in food applications.
Disha, Mitali Madhumita, Dharmender Kumar, Pramod Kumar Prabhakar   +3 more
wiley   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Synthesis and evaluation of aza-peptidyl inhibitors of the lysosomal asparaginyl endopeptidase, legumain

Bioorganic & Medicinal Chemistry Letters, 2011
Legumain or asparaginly endopeptidase (AEP) is a lysosomal cysteine protease with a high level of specificity for cleavage of protein substrates after an asparagine residue.
Jiyoun Lee, M. Bogyo
semanticscholar   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

Multistep Autoactivation of Asparaginyl Endopeptidase in Vitro and in Vivo*

Journal of Biological Chemistry, 2003
Mammalian asparaginyl endopeptidase (AEP) or legumain is a recently discovered lysosomal cysteine protease that specifically cleaves after asparagine residues.
D. N. Li, S. Matthews, A. Antoniou, D. Mazzeo, C. Watts   +4 more
semanticscholar   +1 more source

Rosellinia necatrix infection induces differential gene expression between tolerant and susceptible avocado rootstocks.

PLoS ONE, 2019
Rosellinia necatrix is the causal agent of avocado white root rot (WRR). Control of this soil-borne disease is difficult, and the use of tolerant rootstocks may present an effective method to lessen its impact.
Adela Zumaquero, Elsa Martínez-Ferri, Antonio J Matas, Bianca Reeksting, Nicholas A Olivier, Fernando Pliego-Alfaro, Araceli Barceló, Nöelani van den Berg, Clara Pliego   +8 more
doaj   +1 more source

Impact of Lactic Acid Bacteria Fermentation on the Nutritional and Sensory Quality of Arthrospira platensis Beverages

eFood, Volume 7, Issue 4, August 2026.
To improve the consumer appeal of Arthrospira platensis, this study utilized probiotic fermentation to mitigate its strong seaweed‐like aroma. Using Lactiplantibacillus plantarum significantly boosted amino acids, introduced novel volatiles, and enhanced umami flavors.
Hasim Kelebek, Turkan Uzlasir, Pınar Kadiroglu, Hatice Kübra Sasmaz, Serkan Selli, Matteo Bordiga   +5 more
wiley   +1 more source

STAT3 ameliorates truncated tau-induced cognitive deficits

Neural Regeneration Research, 2023
Proteolytic cleavage of tau by asparagine endopeptidase (AEP) creates tau-N368 fragments, which may drive the pathophysiology associated with synaptic dysfunction and memory deterioration in the brain of Alzheimer's disease patients.
Bing-Ge Zhang, Huali Wan, Maimaitijiang Maierwufu, Qian Liu, Ting Li, Ye He, Xin Wang, Gong-Ping Liu, Xiaoyue Hong, Qiong Feng   +9 more
semanticscholar   +1 more source

Recombinant Fungal Aspartic Endopeptidases: Insights into Protein Hydrolysis and Combined Effect with Pepsin for Animal Feed Application

Journal of Agricultural and Food Chemistry
Protein hydrolysis under acidic conditions can improve the product quality, nutrient availability, and cost efficiency, particularly when neutral or alkaline enzymes are ineffective. Six fungal aspartic endopeptidases (FAPs) were recombinantly expressed as active enzymes in Komagataella phaffi, with peak activity between 30-50 °C and pH 3.0-4.0 ...
Uzair Ahmed, Tobias Stadelmann, Daniel Heid, Katharina Bleher, Frank Kirschhöfer, Hannah Kratz, Katrin Ochsenreither, Thomas Eisele   +7 more
openaire   +4 more sources

Seaweed‐Derived Proteolytic Extracts as Natural Interfacial Stabilizers for Oxidatively Sensitive DHA‐Rich Oil‐in‐Water Emulsions

European Journal of Lipid Science and Technology, Volume 128, Issue 8, August 2026.
Red seaweed extracts have potential to protect DHA‐rich emulsions against oxidation while maintaining their physical stability. Their combined antioxidant and interfacial properties make them promising clean‐label ingredients for omega‐3‐enriched foods.
Sakhi Ghelichi, Behdad Shokrollahi Yancheshmeh, Mona Hajfathalian, Seyed Hossein Helalat, Charlotte Jacobsen   +4 more
wiley   +1 more source