Results 11 to 20 of about 51,717 (226)
Real-World Use of Rezafungin for the Treatment of Challenging Aspergillus Infections. [PDF]
ABSTRACT Background Aspergillus infections can pose significant treatment challenges, due in part to increasing triazole resistance. Clinical insight is needed to understand the potential for rezafungin, a next‐generation echinocandin with once‐weekly dosing, to address some limitations of current treatments for Aspergillus infections.
Stone N +9 more
europepmc +2 more sources
Azole-Resistant Aspergillosis: An Emerging Diagnostic and Therapeutic Challenge in Paediatrics. [PDF]
ABSTRACT Introduction Invasive aspergillosis (IA) represents one of the most frequent invasive fungal infections in paediatric patients with risk factors. An increase in cases of azole‐resistant IA has been reported in adult patients. The aim of this study is to present a series of 11 cases of paediatric patients with this pathology.
Mendoza-Palomar N +14 more
europepmc +2 more sources
Peroral amphotericin B polymer nanoparticles lead to comparable or superior in vivo antifungal activity to that of intravenous Ambisome® or Fungizone™ [PDF]
Background: Despite advances in the treatment, the morbidity and mortality rate associated with invasive aspergillosis remains unacceptably high (70–90%) in immunocompromised patients.
M N V Ravi Kumar +20 more
core +5 more sources
Invasive pulmonary aspergillosis in critically ill patients with pneumonia due to COVID-19, influenza, and communityacquired pneumonia: A prospective observational study [PDF]
Background and Purpose: Influenza A and SARS-CoV-2 are risk factors for invasive pulmonary aspergillosis. Both influenza-associated pulmonary aspergillosis and COVID-19-associated pulmonary aspergillosis result in high mortality and poor clinical ...
Ahsan Syed +7 more
doaj +1 more source
Orbital Aspergillosis: Voriconazole – The New Standard Treatment
Background/Aim: To describe a case of invasive orbital aspergillosis and evaluate treatments and outcomes. Methods: A case report and review of orbital aspergillosis treatment with voriconazole in the English language literature. Conclusion: Amphotericin
Derek H. Ohlstein +4 more
doaj +2 more sources
Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development [PDF]
Aspergillosis is a common fungal infection with systemic characteristics, which is caused by various species of Aspergillus. The infection could develop in immunocompromised and immunocompetent patients under specific circumstances. Based on the clinical
Ali AL-Janabi
doaj +1 more source
Invasive sinus aspergillosis is a rare life-threatening condition usually found in immunocompromised patients. The fungus spreads from paranasal sinuses into the central nervous system by direct extension or through blood vessels. Perineural spread is an
Maruša Mencinger, MD +2 more
doaj +1 more source
Objectives: We aimed to identify the frequency and risk factors for disease relapse following cessation of antifungal therapy in CPA. Methods: This retrospective audit at the National Aspergillosis Centre, Manchester, UK assessed outcomes for patients ...
Felix Bongomin +5 more
doaj +1 more source
Aspergillosis in an African grey parrot [PDF]
Aspergillosis is an uncommon disease except in birds. A case of aspergillosis in a 26 year old female African grey parrot is presented and used to illustrate the typical clinical presentation and management of aspergillosis. Pathogenesis of the disease
Stuckey, Joyce
core +4 more sources
Clinical periodontal diagnosis
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi +5 more
wiley +1 more source

