Results 21 to 30 of about 45,302 (241)

Caspofungin Cerebral Penetration and Therapeutic Efficacy in Experimental Cerebral Aspergillosis. [PDF]

open access: yes, 2022
Despite best available therapy, cerebral aspergillosis is an often-lethal complication of disseminated aspergillosis. There is an urgent need to expand the currently limited therapeutic options.
Aregger, Andrea   +4 more
core   +1 more source

Pulmonary Aspergillosis [PDF]

open access: yesSeminars in Respiratory and Critical Care Medicine, 2008
As the population of patients with prolonged neutropenia, those receiving hematopoietic stem cell transplantation or lung transplantation, or those with human immunodeficiency virus or acquired immunodeficiency syndrome continues to increase, the rising incidence of pulmonary aspergillosis is unlikely to diminish.
George R, Thompson, Thomas F, Patterson
openaire   +2 more sources

Current Promising Therapeutic Targets for Aspergillosis Treatment

open access: yes, 2021
Aspergillosis is a fungal disease caused by different species of Aspergillus. They live in soil,dust and decomposed material. Number of Aspergillus species found till now is about 300 and more are still to be identified.
Shweta Srivastava   +3 more
core   +1 more source

Late-onset isavuconazole-induced liver injury

open access: yesMedical Mycology Case Reports, 2018
Antifungal agents account for approximately 3% of Drug-Induced Liver Injury (DILI) cases. Isavuconazole is a novel triazole, and experience with long-term use of it is lacking.
Felix Bongomin   +4 more
doaj   +1 more source

Successful long-term terbinafine therapy in an asthmatic patient with Aspergillus sensitization and bronchiectasis

open access: yesMedical Mycology Case Reports, 2017
Severe asthma with fungal sensitization (SAFS) is estimated to affect ~25% of patients with poorly controlled asthma. Tri-azole therapy is effective in only 60–80% and side effects are common.
Isabel Rodriguez-Goncer   +2 more
doaj   +1 more source

Nebulised N-Acetylcysteine for Unresponsive Bronchial Obstruction in Allergic Brochopulmonary Aspergillosis: A Case Series and Review of the Literature

open access: yesJournal of Fungi, 2018
Many chronic lung diseases are characterized by the hypersecretion of mucus. In these conditions, the administration of mucoactive agents is often indicated as adjuvant therapy. N-acetylcysteine (NAC) is a typical example of a mucolytic agent.
Akaninyene Otu   +2 more
doaj   +1 more source

Metagenomic next-generation sequencing for the diagnosis of pulmonary aspergillosis in non-neutropenic patients: a retrospective study

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
This study aimed to obtain further in-depth information on the value of metagenomic next-generation sequencing (mNGS) for diagnosing pulmonary aspergillosis in non-neutropenic patients.
Shujun Bao   +4 more
doaj   +1 more source

Immunodiagnosis of aspergillosis [PDF]

open access: yesClinical Microbiology Reviews, 1991
Aspergillus species are ubiquitous fungi and have been implicated as the causative agents of a variety of lung disorders in humans. These disorders include allergic, saprophytic, and systemic manifestations. The allergic disorders mainly affect atopic persons, and invasive or systemic diseases affect immunosuppressed individuals.
V P, Kurup, A, Kumar
openaire   +2 more sources

EXPECT THE UNEXPECTED: INVASIVE CENTRAL NERVOUS SYSTEM (CNS) ASPERGILLOSIS IN NON-NEUTROPENIC PATIENTS – A CASE SERIES OF 15 PATIENTS FROM INDIA

open access: yesInternational Journal of Infectious Diseases, 2023
Intro: Invasive aspergillosis of CNS is a severe form of aspergillosis & is associated with high mortality. Most of these cases are suspected & diagnosed in neutropenic patients.
A. Ravindra   +5 more
doaj   +1 more source

Aspergillosis: interactions of Aspergillus fumigatus andHuman Airway Cells [PDF]

open access: yes, 2013
Aspergillus fumigatus is a filamentous fungus that colonises the lungs of immunosuppressed patients and causes aspergillosis. Despite recent medical advances, infectious diseases caused by opportunistic pathogens such as A. fumigatus are still one of the
Safari, M.
core   +1 more source

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