Influence of low‐dose aspirin, resistance exercise, and sex on human skeletal muscle PGE2/COX pathway activity [PDF]
Physiological Reports, 2021 Prostaglandin (PG) E2 has been linked to increased inflammation and attenuated resistance exercise adaptations in skeletal muscle. Nonaspirin cyclooxygenase (COX) inhibitors have been shown to reduce these effects.
Masatoshi Naruse +10 more
doaj +4 more sources
Frequency of Aspirin Resistance in Ischemic Stroke Patients and Healthy Controls from Colombia [PDF]
Stroke Research and Treatment, 2021 Objective. To evaluate the aspirin resistance prevalence in patients with previous ischemic cerebrovascular disease undergoing aspirin therapy for secondary prevention. Materials and Methods.
Alejandro Roman-Gonzalez +12 more
doaj +2 more sources
Long Non-Coding RNA H19 Positively Associates With Aspirin Resistance in the Patients of Cerebral Ischemic Stroke [PDF]
Frontiers in Pharmacology, 2020 Background and purposeAspirin is a novel anti-platelet drug that is intensively recommended for the prevention and treatment of cerebral ischemic stroke.
Jue Wang +8 more
doaj +2 more sources
Epoxidase inhibitor-aspirin resistance and the relationship with genetic polymorphisms: a review [PDF]
Journal of International Medical ResearchStrokes are the leading cause of death in most regions of the world. Epoxidase inhibitors include the drug aspirin (acetylsalicylic acid). Aspirin is widely used as first-line treatment for the prevention of cardiovascular and cerebrovascular diseases in
Xiaolin Hou
doaj +2 more sources
Factors Associated with Aspirin Resistance in Hong Kong Chinese Patients with Stable Coronary Heart Disease Using the Multiplate® Analyzer and Serum Thromboxane B2 [PDF]
Pharmaceutics, 2022 Introduction: Aspirin resistance may be associated with various conditions. We measured serum thromboxane B2 (TXB2) and platelet function using the Multiplate® Analyzer with arachidonic acid (ASPI) in patients on long term aspirin therapy to identify ...
Weiwei Zeng +7 more
doaj +2 more sources
Resistance to aspirin is increased by ST-elevation myocardial infarction and correlates with adenosine diphosphate levels [PDF]
Thrombosis Journal, 2005 Background To be fully activated platelets are dependent on two positive feedback loops; the formation of thromboxane A2 by cyclooxygenase in the platelets and the release of ADP.
Öhlin Hans +4 more
doaj +2 more sources
Low miR‐19b‐1‐5p Expression Is Related to Aspirin Resistance and Major Adverse Cardio‐ Cerebrovascular Events in Patients With Acute Coronary Syndrome [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Because of a nonresponse to aspirin (aspirin resistance), patients with acute coronary syndrome (ACS) are at increased risk of developing recurrent event.
Sandeep Singh +12 more
doaj +2 more sources
Mechanism of Improving Aspirin Resistance: Blood-Activating Herbs Combined With Aspirin in Treating Atherosclerotic Cardiovascular Diseases. [PDF]
Front Pharmacol, 2021 Zhao Y, Yang S, Wu M.
europepmc +3 more sources
CLINICAL SIGNIFICANCE OF ASPIRIN RESISTANCE IN PATIENTS WITH CARDIO-VASCULAR DISEASES
Рациональная фармакотерапия в кардиологии, 2016 Atherothrombosis is a complication of ischemic heart disease, and it leads to development of acute coronary syndrome. Atherothrombosis is characterized by sudden destruction of atherosclerotic plaque, which results into platelets activation and thrombus ...
P. J. Dovgalevsky +2 more
doaj +3 more sources
Factors associated with aspirin resistance in diabetic patients: A metabolic and inflammatory profile analysis. [PDF]
PLoS ONEBackgroundDiabetes mellitus (DM) is strongly linked to both first-time and recurrent atherosclerotic thrombotic events. Although aspirin (ASA) is commonly used to prevent cardiovascular diseases, studies have shown that ASA does not significantly reduce ...
Bo Chen +5 more
doaj +2 more sources