Results 21 to 30 of about 88,050 (335)

Aspirin resistance in patients with acute coronary syndrome. Part 2

Кардиоваскулярная терапия и профилактика, 2011
Aim. In patients with acute coronary syndrome (ACS), to investigate the prevalence of aspirin resistance, its clinical features, prognostic effects, and potential correction. Material and methods.
N. S. Frolova, R. M. Shakhnovich, E. M. Kaznacheeva, O. V. Sirotkina, A. B. Dobrovolskyi   +4 more
doaj   +1 more source

TRUE RESISTANCE AND PSEUDORESISTANCE TO ASPIRIN

Рациональная фармакотерапия в кардиологии, 2015
Low dose aspirin reduces the secondary incidence of myocardial infarction and stroke. Drug resistance to aspirin might result in treatment failure.
A. I. Martynov, E. V. Akatova, I. V. Urlayeva, O. P. Nicolin   +3 more
doaj   +3 more sources

Decreased turnover aspirin resistance by bidaily aspirin intake and efficient cytoreduction in myeloproliferative neoplasms

Platelets, 2018
Essential thrombocythemia (ET) and polycythemia vera (PV) are myeloproliferative neoplasms (MPN) with an increased risk of arterial and venous thrombosis.
Andréas Perrier-Cornet, Jean-Christophe Ianotto, Fanny Mingant, Maëla Perrot, Eric Lippert, Hubert Galinat   +5 more
doaj   +1 more source

Mechanistic view into the therapeutic effect, anticancer potential and the adverse effect of aspirin [PDF]

MATEC Web of Conferences
In this research, the working mechanism behind the therapeutic effect of aspirin will be discussed in detail. Aspirin will also be assessed as a promising drug to treat cancerous cells in the future.
Ouyang Juan
doaj   +1 more source

Platelet Function Assays for the Diagnosis of Aspirin Resistance

Platelets, 2022
Aspirin, an antiplatelet drug, is commonly used at low doses for numerous indications, including prophylaxis of cardiovascular, neurovascular, and venous thromboembolic events.
Nameer Van Oosterom, Michael Barras, Neil Cottrell, Robert Bird   +3 more
doaj   +1 more source

Decreased sensitivity to aspirin is associated with altered polyamine metabolism in human prostate cancer cells [PDF]

, 2015
Acknowledgments We thank NHS Grampian for financial support of this work.Peer reviewedPublisher ...
Cameron, Gary A., Li, Jun, Wallace, Heather M.   +2 more
core   +1 more source

'Aspirin resistance' or treatment non-compliance: Which is to blame for cardiovascular complications?

Journal of Translational Medicine, 2008
Aspirin is one of the 'cornerstone' drugs in our current management of cardiovascular disorders. However, despite the prescription of aspirin recurrent vascular events still occur in 10–20% of patients.
Shantsila Eduard, Lip Gregory YH
doaj   +1 more source

In Silico screening of nonsteroidal anti-inflammatory drugs and their combined action on Prostaglandin H Synthase-1 [PDF]

, 2010
The detailed kinetic model of Prostaglandin H Synthase-1 (PGHS-1) was applied to in silico screening of dose-dependencies for the different types of nonsteroidal anti-inflammatory drugs (NSAIDs), such as: reversible/irreversible, nonselective/selective ...
Demin, Oleg, Goltsov, Alexey, Goltsov, Gregory, Goryanin, Igor, Humphery-Smith, Ian, Lebedeva, Galina   +5 more
core   +4 more sources

Aspirin resistance: causes, clinical significance, correction

Mìžnarodnij Endokrinologìčnij Žurnal, 2022
Aspirin is the most frequently prescribed antiplatelet agent today. It exerts its antiplatelet effect by irreversible inactivation of the platelet cyclooxygenase-1, resulting in an irreversible inhibition of thromboxane-A2 formation. The clinical benefit
G.F. Gendeleka, A.N. Gendeleka
doaj   +1 more source

Aspirin resistance and ischemic heart disease on Iranian experience

Advanced Biomedical Research, 2012
Background: Coronary artery disease (CAD) and myocardial infarction are the most common causes of mortality and morbidity all over the world.
Masoumeh Sadeghi, Afsoon Emami, Naghmeh Ziyaei, Majid Yaran, Allahyar Golabchi, Azam Sadeghi   +5 more
doaj   +1 more source