Results 31 to 40 of about 42,260 (251)

Mechanistic view into the therapeutic effect, anticancer potential and the adverse effect of aspirin [PDF]

MATEC Web of Conferences
In this research, the working mechanism behind the therapeutic effect of aspirin will be discussed in detail. Aspirin will also be assessed as a promising drug to treat cancerous cells in the future.
Ouyang Juan
doaj   +1 more source

Platelet Function Assays for the Diagnosis of Aspirin Resistance

Platelets, 2022
Aspirin, an antiplatelet drug, is commonly used at low doses for numerous indications, including prophylaxis of cardiovascular, neurovascular, and venous thromboembolic events.
Nameer Van Oosterom, Michael Barras, Neil Cottrell, Robert Bird   +3 more
doaj   +1 more source

'Aspirin resistance' or treatment non-compliance: Which is to blame for cardiovascular complications?

Journal of Translational Medicine, 2008
Aspirin is one of the 'cornerstone' drugs in our current management of cardiovascular disorders. However, despite the prescription of aspirin recurrent vascular events still occur in 10–20% of patients.
Shantsila Eduard, Lip Gregory YH
doaj   +1 more source

Aspirin resistance: causes, clinical significance, correction

Mìžnarodnij Endokrinologìčnij Žurnal, 2022
Aspirin is the most frequently prescribed antiplatelet agent today. It exerts its antiplatelet effect by irreversible inactivation of the platelet cyclooxygenase-1, resulting in an irreversible inhibition of thromboxane-A2 formation. The clinical benefit
G.F. Gendeleka, A.N. Gendeleka
doaj   +1 more source

Aspirin resistance and ischemic heart disease on Iranian experience

Advanced Biomedical Research, 2012
Background: Coronary artery disease (CAD) and myocardial infarction are the most common causes of mortality and morbidity all over the world.
Masoumeh Sadeghi, Afsoon Emami, Naghmeh Ziyaei, Majid Yaran, Allahyar Golabchi, Azam Sadeghi   +5 more
doaj   +1 more source

The association of four common polymorphisms from four candidate genes (COX-1, COX-2, ITGA2B, ITGA2) with aspirin insensitivity: a meta-analysis. [PDF]

PLoS ONE, 2013
OBJECTIVE: Evidence is mounting suggesting that a strong genetic component underlies aspirin insensitivity. To generate more information, we aimed to evaluate the association of four common polymorphisms (rs3842787, rs20417, rs201184269, rs1126643) from ...
Zhiyuan Weng, Xiaobo Li, Yuqiong Li, Jinxiu Lin, Feng Peng, Wenquan Niu   +5 more
doaj   +1 more source

Aspirin resistance in patients with ischemic stroke

Southern Clinics of Istanbul Eurasia, 2019
INTRODUCTION[|]Aspirin is the basic agent of antithrombotic treatment in ischemic cerebrovascular disease (CVD) patients. However several patients don't respond to treatment and therefore aspirin resistance term has been used lately.
Anıl Bulut, Sultan Çağırıcı, Vildan Yayla, Murat Çabalar, Songül Şenadım   +4 more
doaj   +1 more source

PENGARUH DIABETES MELLITUS TERHADAP RESISTENSI ASPIRIN PADA PASIEN STROKE ISKEMIK DI RUMAH SAKIT BETHESDA YOGYAKARTA

Pharmaciana, 2014
The secondary prevention of ischemic stroke can be implemented by giving aspirin. However, some cases of aspirin resistance have been found. The purpose of this study was to examine the influence of diabetes mellitus on the risk of aspirin resistance ...
Hardi Astuti Witasari, Rizaldy Taslim Pinzon, Erna Kristin   +2 more
doaj   +1 more source

Aspirin Resistance

Advances in Hematology, 2009
The development of adverse cardiovascular events despite aspirin use has established an interest in a possible resistance to the drug. Several definitions have been set and various laboratory testing modalities are available. This has led to a wide range
Khaled Mansour, Ali T. Taher, Khaled M. Musallam, Samir Alam   +3 more
doaj   +1 more source

Aspirin and clopidogrel resistance; a neglected gap in stroke and cardiovascular practice in Iran: a systematic review and meta-analysis

Thrombosis Journal, 2023
Objective Antiplatelet drugs, such as Aspirin and Clopidogrel (Plavix) are effective in the primary prevention of thromboembolic events. They are commonly used to reduce the risk of recurrence of thromboembolism.
Mohammad Parsa-kondelaji, Hassan Mansouritorghabeh   +1 more
doaj   +1 more source