Results 171 to 180 of about 5,002 (185)

Targeting the Response to Arginine Starvation in ASS1-Deficient Sarcomas

2017
One of the hallmarks of cancer is the dysregulation of cellular metabolism and bioenergetics that occur during tumorigenesis. Among the most well-known alterations in cellular metabolism is the Warburg effect, whereby cancer cells preferentially metabolize glucose into lactic acid, rather than metabolism through the TCA cycle and subsequent oxidative ...
openaire   +2 more sources

[ASS1 gene mutation in a neonate with citrullinemia type I].

Zhonghua er ke za zhi = Chinese journal of pediatrics, 2015
To identify the genetic mutation in ASS1 gene in a Chinese family with citrullinemia typeI, which may provide a basis for the diagnosis and genetic counseling.Genomic DNA was isolated from peripheral blood samples of the family members. Mutation analysis of ASS1 gene was carried out by PCR and Sanger sequencing.
Bobo, Xie, Rongyu, Chen, Jin, Wang, Jingsi, Luo, Wang, Li, Shaoke, Chen   +5 more
openaire   +1 more source

[Genetic analysis of ASS1, ASL and SLC25A13 in citrullinemia patients].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2014
To detect potential mutations of Y9ASS1, ASL and SLC25A13 genes in four patients manifesting citrullinemia.Genomic DNA was extracted from peripheral blood leukocytes. Exons and their flanking sequences of the three genes were amplified with polymerase chain reaction and subjected to direct DNA sequencing.Based on DNA sequence analysis, one case was ...
Pengqiang, Wen, Zhanling, Chen, Guobing, Wang, Xiaohong, Liu, Li, Chen, Shuli, Chen, Lisheng, Wan, Dong, Cui, Yue, Shang, Chengrong, Li   +9 more
openaire   +1 more source

[ASS1 mutation leading to citrullinemia I in a Chinese Han family].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2012
To investigate potential mutation of the ASS1 gene in a male infant with acute citrullinemia type I.Genomic DNA was prepared from peripheral blood samples of the family members. Mutation analysis of the 14 ASS1 exons was carried out by PCR and direct DNA sequencing.A homozygous missense mutation of c.970G>A located in exon 13, which results in p.G324S,
Ping, Hu, Xiao-yan, Zhou, Ding-yuan, Ma, Yun, Sun, Xiao-juan, Zhang, Shu-ping, Han, Zhang-bin, Yu, Tao, Jiang, Yu-lin, Chen, Zhengfeng, Xu   +9 more
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FXR/ASS1 Axis Attenuates the TAA-Induced Liver Injury Through Arginine Metabolism

Biochemical and Biophysical Research Communications, 2022
Weicheng Liang, Xue Zhou, Zhiqiang Ye
exaly  

Detection of Depression Marker ASS1 in Urine by Gold Nanoparticles Based Dual Epitope-Peptides Imprinted Sensor

Analytica Chimica Acta, 2023
Yongling Du, Fang-Di Hu
exaly  

Serum Extracellular Vesicle-Derived ASS1 Is a Promising Predictor for the Occurrence of HEV-ALF

Journal of Medical Virology, 2023
Jian Wu, Bai Ling, Chun Jiang
exaly  

BPS2026 – Toward a structural basis for ASS1 regulation

Biophysical Journal
Danya Abdallah, Jeanan Ahmad, Jerrade Domingo, Lucky Gurung, Michelle Von Merta-Sustarich, Ryan Leung, Eric R. Greene   +6 more
openaire   +1 more source

Mutations and Polymorphisms in the Human Argininosuccinate Synthetase (ASS1) Gene

Human Mutation, 2009
Johannes Häberle
exaly  

Deficiency in Expression and Epigenetic DNA Methylation of ASS1 Gene in Nasopharyngeal Carcinoma: Negative Prognostic Impact and Therapeutic Relevance

Tumor Biology, 2014
Hsuan-Ying Huang, Chien-Feng Li, Sung-Wei Lee   +2 more
exaly