Results 31 to 40 of about 5,490,229 (291)

Brain region networks for the assimilation of new associative memory into a schema

Molecular Brain, 2022
Alterations in long-range functional connectivity between distinct brain regions are thought to contribute to the encoding of memory. However, little is known about how the activation of an existing network of neocortical and hippocampal regions might ...
Tomonori Takeuchi, Makoto Tamura, Dorothy Tse, Yasushi Kajii, Guillén Fernández, Richard G. M. Morris   +5 more
doaj   +1 more source

An Account of Models of Molecular Circuits for Associative Learning with Reinforcement Effect and Forced Dissociation

Sensors, 2022
The development of synthetic biology has enabled massive progress in biotechnology and in approaching research questions from a brand-new perspective. In particular, the design and study of gene regulatory networks in vitro, in vivo, and in silico have ...
Zonglun Li, Alya Fattah, Peter Timashev, Alexey Zaikin   +3 more
doaj   +1 more source

The Vital Role of Central Executive Network in Brain Age: Evidence From Machine Learning and Transcriptional Signatures

Frontiers in Neuroscience, 2021
Recent studies combining neuroimaging with machine learning methods successfully infer an individual’s brain age, and its discrepancy with the chronological age is used to identify age-related diseases.
Keke Fang, Shaoqiang Han, Yuming Li, Jing Ding, Jilian Wu, Wenzhou Zhang   +5 more
doaj   +1 more source

ANALYSIS OF THE INTERACTIONS OF NEURONAL APOPTOSIS GENES IN THE ASSOCIATIVE GENE NETWORK OF PARKINSON’S DISEASE

Вавиловский журнал генетики и селекции, 2018
Parkinson’s disease (PD) affects an estimated 7–10 million people worldwide and 210000 people in Russia. PD is accompanied by degeneration of dopaminergic neurons and because of that neuronal apoptosis is an important factor in this disease.
M. A. Yankina, O. V. Saik, P. S. Demenkov, E. K. Khusnutdinova, E. I. Rogaev, I. N. Lavrik, V. А. Ivanisenko   +6 more
doaj   +1 more source

Network and pathway-based analyses of genes associated with osteoporosis

Medicine, 2020
Abstract Osteoporosis (OP) is a disease characterized by bone mass loss, bone microstructure damage, increased bone fragility, and easy fracture. The molecular mechanism underlying OP remains unclear. In this study, we identified 217 genes associated with OP, and formed a gene set [OP-related genes gene set (OPgset)]
Gu, Huijie, Huang, Zhongyue, Chen, Guangnan, Zhou, Kaifeng, Zhang, Yiming, Chen, Jiong, Xu, Jun, Yin, Xiaofan   +7 more
openaire   +2 more sources

THE SOLANUM TUBEROSUM KNOWLEDGE BASE: THE SECTION ON MOLECULAR-GENETIC REGULATION OF METABOLIC PATHWAYS

Вавиловский журнал генетики и селекции, 2018
Rapid development of high-performance genomic, transcriptomic, proteomic and metabolic technologies led to an information explosion in the field of plant biology and agrobiology.
T. V. Ivanisenko, O. V. Saik, P. S. Demenkov, V. K. Khlestkin, E. K. Khlestkina, N A. Kolchanov, V. А. Ivanisenko   +6 more
doaj   +1 more source

Multivariate associative patterns between the gut microbiota and large-scale brain network connectivity

Gut Microbes, 2021
Research on the gut–brain axis has accelerated substantially over the course of the last years. Many reviews have outlined the important implications of understanding the relation of the gut microbiota with human brain function and behavior.
N. Kohn, J. Szopinska-Tokov, A. Llera Arenas, C.F. Beckmann, A. Arias-Vasquez, E Aarts   +5 more
doaj   +1 more source

Combining evidence, biomedical literature and statistical dependence: new insights for functional annotation of gene sets

BMC Bioinformatics, 2006
Background Large-scale genomic studies based on transcriptome technologies provide clusters of genes that need to be functionally annotated. The Gene Ontology (GO) implements a controlled vocabulary organised into three hierarchies: cellular components ...
Burgun Anita, Galibert Marie-Dominique, de Tayrac Marie, Chicault Celine, Monnier Annabelle, Aubry Marc, Mosser Jean   +6 more
doaj   +1 more source

Protein Network for Associating Genes with Dementia

International Journal of Computer Applications, 2013
Association between causal genes and their genetic diseases is an important problem concerning human health. Linkage analysis is such a method that can identify which unknown disease genes are located in chromosomal region out of hundreds of candidate genes according to their functions, interactions, and pathways which is good identification of genes ...
Ravi Bhushan Mishra, Brijendra Gupta
openaire   +1 more source

Regulatory and sequence evolution in response to selection for improved associative learning ability in Nasonia vitripennis

BMC Genomics, 2018
Background Selection acts on the phenotype, yet only the genotype is inherited. While both the phenotypic and genotypic response to short-term selection can be measured, the link between these is a major unsolved problem in evolutionary biology, in ...
Ken Kraaijeveld, Vicencio Oostra, Maartje Liefting, Bregje Wertheim, Emile de Meijer, Jacintha Ellers   +5 more
doaj   +1 more source