Results 1 to 10 of about 572 (133)

ANDDigest: A New Web-Based Module of ANDSystem for the Search of Knowledge in the Scientific Literature [PDF]

BMC Bioinformatics, 2020
Background The rapid growth of scientific literature has rendered the task of finding relevant information one of the critical problems in almost any research.
Pavel S Demenkov, Timofey V Ivanisenko, Nikita V Ivanisenko   +2 more
exaly   +7 more sources

Prediction of interactions between the SARS-CoV-2 ORF3a protein and small-molecule ligands using the AND-System cognitive platform, graph neural networks, and molecular [PDF]

Вавиловский журнал генетики и селекции
In recent years, artificial intelligence methods based on the analysis of heterogeneous graphs of biomedical networks have become widely used for predicting molecular interactions.
T. V. Ivanisenko, P. S. Demenkov, M. A. Kleshchev, V. A. Ivanisenko   +3 more
doaj   +4 more sources

Gene networks for use in metabolomic data analysis of blood plasma from patients with postoperative delirium [PDF]

Вавиловский журнал генетики и селекции, 2023
Postoperative delirium (POD) is considered one of the most severe complications, resulting in impaired cognitive function, extended hospitalization, and higher treatment costs.
V. A. Ivanisenko, N. V. Basov, A. A. Makarova, A. S. Venzel, A. D. Rogachev, P. S. Demenkov, T.  V. Ivanisenko, M. A. Kleshchev, E. V. Gaisler, G. B. Moroz, V. V. Plesko, Y. S. Sotnikova, Y. V. Patrushev, V. V. Lomivorotov, N. A. Kolchanov, A. G. Pokrovsky   +15 more
doaj   +2 more sources

Rational bioinformatic approach to the analysis of functional properties of metabolites of probiotic microorganisms based on gene network reconstruction [PDF]

Вавиловский журнал генетики и селекции
An important direction in industrial microbiology is the development of probiotic strains with valuable consumer properties. The probiotic industry is currently one of the most rapidly developing segments of the food and pharmaceutical sectors.
V. A. Ivanisenko, T. M. Khlebodarova, M. A. Kleshchev, A. R. Volyanskaya, I. V. Yatsyk, A. V. Adamovskaya, T. V. Ivanisenko, P. S. Demenkov, N. A. Kolchanov   +8 more
doaj   +2 more sources

Associative gene networks reveal novel candidates important for ADHD and dyslexia comorbidity [PDF]

BMC Medical Genomics, 2023
Background Attention deficit hyperactivity disorder (ADHD) is commonly associated with developmental dyslexia (DD), which are both prevalent and complicated pediatric neurodevelopmental disorders that have a significant influence on children’s learning ...
HE Hongyao, JI Chun, Gao Xiaoyan, Liu Fangfang, Zhang Jing, Zhong Lin, Zuo Pengxiang, Li Zengchun   +7 more
doaj   +2 more sources

Reconstruction of the regulatory hypermethylation network controlling hepatocellular carcinoma development during hepatitis C viral infection [PDF]

Journal of Integrative Bioinformatics, 2023
Hepatocellular carcinoma (HCC) has been associated with hepatitis C viral (HCV) infection as a potential risk factor. Nonetheless, the precise genetic regulatory mechanisms triggered by the virus, leading to virus-induced hepatocarcinogenesis, remain ...
Antropova Evgeniya A., Khlebodarova Tamara M., Demenkov Pavel S., Volianskaia Anastasiia R., Venzel Artur S., Ivanisenko Nikita V., Gavrilenko Alexandr D., Ivanisenko Timofey V., Adamovskaya Anna V., Revva Polina M., Kolchanov Nikolay A., Lavrik Inna N., Ivanisenko Vladimir A.   +12 more
doaj   +2 more sources

SmartCrop: knowledge base of molecular genetic mechanisms of rice and wheat adaptation to stress factors [PDF]

Вавиловский журнал генетики и селекции
The study of molecular genetic mechanisms of plant responses to specific growth conditions and stress factors is a central focus of scientific research aimed at developing new valuable crop varieties, particularly rice and wheat.
P. S. Demenkov, T. V. Ivanisenko, M. A. Kleshchev, E. A. Antropova, I. V. Yatsyk, A. R. Volyanskaya, A. V. Adamovskaya, A. V. Maltseva, A. S. Venzel, H. Chao, M. Chen, V. A. Ivanisenko   +11 more
doaj   +2 more sources

Prioritization of potential pharmacological targets for the development of anti-hepatocarcinoma drugs modulating the extrinsic apoptosis pathway: the reconstruction and analysis of associative gene networks help [PDF]

Вавиловский журнал генетики и селекции, 2023
Hepatocellular carcinoma (HCC) is a common severe type of liver cancer characterized by an extremely aggressive course and low survival rates. It is known that disruptions in the regulation of apoptosis activation are some of the key features inherent in
P. S. Demenkov, E. A. Antropova, A. V. Adamovskaya, E. I. Mishchenko, T. M. Khlebodarova, T. V. Ivanisenko, N. V. Ivanisenko, A. S. Venzel, I. N. Lavrik, V. A. Ivanisenko   +9 more
doaj   +2 more sources

Molecular-genetic pathways of hepatitis C virus regulation of the expression of cellular factors PREB and PLA2G4C, which play an important role in virus replication [PDF]

Вавиловский журнал генетики и селекции, 2023
The participants of Hepatitis C virus (HCV) replication are both viral and host proteins. Therapeutic approaches based on activity inhibition of viral non-structural proteins NS3, NS5A, and NS5B are undergoing clinical trials.
E. L. Mishchenko, A. A. Makarova, E. A. Antropova, A. S. Venzel, T. V. Ivanisenko, P. S. Demenkov, V. A. Ivanisenko   +6 more
doaj   +2 more sources

Reconstruction and analysis of the gene regulatory network for cell wall function in Arabidopsis thaliana L. leaves in response to water deficit [PDF]

Вавиловский журнал генетики и селекции, 2023
The plant cell wall represents the outer compartment of the plant cell, which provides a physical barrier and triggers signaling cascades under the influence of biotic and abiotic stressors.
A. R. Volyanskaya, E. A. Antropova, U. S. Zubairova, P. S. Demenkov, A. S. Venzel, Y. L. Orlov, A. A. Makarova, T. V. Ivanisenko, T. A. Gorshkova, A. R. Aglyamova, N. A. Kolchanov, M. Chen, V. A.  Ivanisenko   +12 more
doaj   +2 more sources