Results 11 to 20 of about 572 (133)

A New Version of the ANDSystem Tool for Automatic Extraction of Knowledge From Scientific Publications With Expanded Functionality for Reconstruction of Associative Gene Networks by Considering Tissue-Specific Gene Expression

BMC Bioinformatics, 2019
Background Consideration of tissue-specific gene expression in reconstruction and analysis of molecular genetic networks is necessary for a proper description of the processes occurring in a specified tissue.
Pavel S Demenkov, Timofey V Ivanisenko, Vladimir A Ivanisenko   +2 more
exaly   +6 more sources

Andsystem in dentistry: a reasoned choice [PDF]

Кубанский научный медицинский вестник, 2015
Currently, therapeutic dentistry is developing by leaps and bounds. With the huge number of new filling materials, techniques that appeared in the dental market, before dentist faces the task proper, reasoned choice.
Yu. A. Makedonova, I. V. Firsova
doaj   +2 more sources

Searching for biological processes as targets for rheumatoid arthritis targeted therapy with AND-System, an integrated software and information platform [PDF]

Вавиловский журнал генетики и селекции
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by joint involvement with progressive destruction of cartilage and bone tissue.
E. L. Mishchenko, I. V. Yatsyk, P. S. Demenkov, A. V. Adamovskaya, T. V. Ivanisenko, M. A. Kleshchev, V. A. Ivanisenko   +6 more
doaj   +4 more sources

Reconstruction and analysis of the gene network regulating apoptosis in hepatocellular carcinoma based on scRNA-seq data and the AND-System knowledge base [PDF]

Вавиловский журнал генетики и селекции
Hepatocellular Carcinoma (HCC) is the most common primary liver cancer characterized by rapid progres­ sion, high mortality rate and therapy resistance.
A. V. Adamovskaya, I. V. Yatsyk, M. A. Kleshchev, P. S. Demenkov, T. V. Ivanisenko, V. A. Ivanisenko   +5 more
doaj   +4 more sources

ANALYSIS OF THE INTERACTIONS OF NEURONAL APOPTOSIS GENES IN THE ASSOCIATIVE GENE NETWORK OF PARKINSON’S DISEASE [PDF]

Вавиловский журнал генетики и селекции, 2018
Parkinson’s disease (PD) affects an estimated 7–10 million people worldwide and 210000 people in Russia. PD is accompanied by degeneration of dopaminergic neurons and because of that neuronal apoptosis is an important factor in this disease.
M. A. Yankina, O. V. Saik, P. S. Demenkov, E. K. Khusnutdinova, E. I. Rogaev, I. N. Lavrik, V. А. Ivanisenko   +6 more
doaj   +2 more sources

Search for New Candidate Genes Involved in the Comorbidity of Asthma and Hypertension Based on Automatic Analysis of Scientific Literature [PDF]

Journal of Integrative Bioinformatics, 2018
Comorbid states of diseases significantly complicate diagnosis and treatment. Molecular mechanisms of comorbid states of asthma and hypertension are still poorly understood.
Saik Olga V., Demenkov Pavel S., Ivanisenko Timofey V., Bragina Elena Yu., Freidin Maxim B., Dosenko Victor E., Zolotareva Olga I., Choynzonov Evgeniy L., Hofestaedt Ralf, Ivanisenko Vladimir A.   +9 more
doaj   +3 more sources

Identification of proteins regulating phenotype-associated genes of M2 macrophages: a bioinformatic analysis [PDF]

Вавиловский журнал генетики и селекции
Macrophages are immune system cells that perform various, often opposing, functions in the organism depending on the incoming microenvironment signals.
E. A. Antropova, I. V. Yatsyk, P. S. Demenkov, T. V. Ivanisenko, V. A. Ivanisenko   +4 more
doaj   +2 more sources

Computer analysis of regulation of hepatocarcinoma marker genes hypermethylated by HCV proteins [PDF]

Вавиловский журнал генетики и селекции, 2023
Hepatitis C virus (HCV) is a risk factor that leads to hepatocellular carcinoma (HCC) development. Epigenetic changes are known to play an important role in the molecular genetic mechanisms of virus-induced oncogenesis.
E. A. Antropova, T. M. Khlebodarova, P. S. Demenkov, A. S. Venzel, N. V. Ivanisenko, A.  D.  Gavrilenko, T.  V. Ivanisenko, A. V. Adamovskaya, P. M. Revva, I. N. Lavrik, V. A. Ivanisenko   +10 more
doaj   +2 more sources

Plasma metabolomics and gene regulatory networks analysis reveal the role of nonstructural SARS-CoV-2 viral proteins in metabolic dysregulation in COVID-19 patients [PDF]

Scientific Reports, 2022
Metabolomic analysis of blood plasma samples from COVID-19 patients is a promising approach allowing for the evaluation of disease progression. We performed the metabolomic analysis of plasma samples of 30 COVID-19 patients and the 19 controls using the ...
V. A. Ivanisenko, E. V. Gaisler, N. V. Basov, A. D. Rogachev, S. V. Cheresiz, T. V. Ivanisenko, P. S. Demenkov, E. L. Mishchenko, O. P. Khripko, Yu. I. Khripko, S. M. Voevoda, T. N. Karpenko, A. J. Velichko, M. I. Voevoda, N. A. Kolchanov, A. G. Pokrovsky   +15 more
doaj   +2 more sources

Role of apoptosis genes in aggression revealed using combined analysis of ANDSystem gene networks, expression and genomic data in grey rats with aggressive behavior

Вавиловский журнал генетики и селекции, 2018
Aggressive behavior in animals plays an important role in protecting the territory, offspring, establishing social hierarchical relations, etc. Increased aggression is observed in a number of diseases ( schizophrenia, bipolar disorder, brain degenerative
A. O. Bragin, O. V. Saik, I. V. Chadaeva, P. S. Demenkov, A. L. Markel, Yu. L. Orlov, E. I.  Rogaev, I. N. Lavrik, V. A. Ivanisenko   +8 more
doaj   +2 more sources