Hemichannels: new roles in astroglial function
The role of astrocytes in brain function has evolved over the last decade, from support cells to active participants in the neuronal synapse through the release of gliotransmitters.
Jimmy eStehberg, Juan Andrés Orellana
doaj +1 more source
Pituitary Adenylate Cyclase-Activating Polypeptide Orchestrates Neuronal Regulation Of The Astrocytic Glutamate-Releasing Mechanism System x\u3csub\u3ec\u3c/sub\u3e\u3csup\u3e−\u3c/sup\u3e [PDF]
Glutamate signaling is achieved by an elaborate network involving neurons and astrocytes. Hence, it is critical to better understand how neurons and astrocytes interact to coordinate the cellular regulation of glutamate signaling.
Albano, Rebecca+7 more
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Distinct molecular interactions mediate neuronal process outgrowth on non-neuronal cell surfaces and extracellular matrices. [PDF]
We have compared neurite outgrowth on extracellular matrix (ECM) constituents to outgrowth on glial and muscle cell surfaces. Embryonic chick ciliary ganglion (CG) neurons regenerate neurites rapidly on surfaces coated with laminin (LN), fibronectin (FN),
Bixby, JL, Reichardt, LF, Tomaselli, KJ
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Astrocytes in Flavivirus Infections [PDF]
Virus infections of the central nervous system (CNS) can manifest in various forms of inflammation, including that of the brain (encephalitis) and spinal cord (myelitis), all of which may have long-lasting deleterious consequences. Although the knowledge of how different viruses affect neural cells is increasing, understanding of the mechanisms by ...
Maja Potokar+2 more
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A Mathematical model for Astrocytes mediated LTP at Single Hippocampal Synapses
Many contemporary studies have shown that astrocytes play a significant role in modulating both short and long form of synaptic plasticity. There are very few experimental models which elucidate the role of astrocyte over Long-term Potentiation (LTP ...
A Araque+97 more
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Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons [PDF]
Perinatal Asphyxia (PA) represents an important cause of severe neurological deficits including delayed mental and motor development, epilepsy, major cognitive deficits and blindness.
Barreto, George E.+5 more
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Amines, Astrocytes, and Arousal [PDF]
Amine neurotransmitters, such as noradrenaline, mediate arousal, attention, and reward in the CNS. New data suggest that, from flies to mammals, a major mechanism for amine transmitter action is to raise astrocyte [Ca2+]i and release gliotransmitters that modulate neuronal activity and behavior.
Bazargani, N, Attwell, D
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Astrocytes mediate analogous memory in a multi-layer neuron-astrocytic network [PDF]
Modeling the neuronal processes underlying short-term working memory remains the focus of many theoretical studies in neuroscience. Here we propose a mathematical model of spiking neuron network (SNN) demonstrating how a piece of information can be maintained as a robust activity pattern for several seconds then completely disappear if no other stimuli
arxiv
Breathing cluster in complex neuron-astrocyte networks [PDF]
Brain activities are featured by spatially distributed neural clusters of coherent firings and a spontaneous switching of the clusters between the synchrony and asynchrony states. Evidences from {\it in vivo} experiments suggest that astrocytes, a type of glial cell regarded previously as providing only structural and metabolic supports to neurons ...
arxiv
The multifaceted role of astrocytes in regulating myelination [PDF]
Astrocytes are the major glial cell of the central nervous system (CNS), providing both metabolic and physical support to other neural cells. After injury, astrocytes become reactive and express a continuum of phenotypes which may be supportive or ...
Barnett, Susan C.+3 more
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