Results 101 to 110 of about 194,703 (370)
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Astrocyte senescence: Evidence and significance
Aging Cell, 2019 Astrocytes participate in numerous aspects of central nervous system (CNS) physiology ranging from ion balance to metabolism, and disruption of their physiological roles can therefore be a contributor to CNS dysfunction and pathology. Cellular senescence,
Justin Cohen, C. Torres
semanticscholar +1 more source
Astrocytes: Powering Memory [PDF]
Cell, 2011 Creating long-term memory requires a cellular program in neurons involving gene expression, protein synthesis, and formation of new synaptic connections. Suzuki et al. (2011) show that astrocytes, glial cells of the brain, play a necessary role in this program by converting glycogen to lactate and transporting it to neurons.
Bezzi Paola, Volterra Andrea
openaire +3 more sources
Advanced Functional Materials, EarlyView.A flexible micro‐electrocorticography array with PEDOT:SS electrodes is shown to be compatible with ultra‐high magnetic field MRI up to 9.4 T. Multimodal brain monitoring is demonstrated by performing simultaneous blood oxygen level‐dependent functional MRI in parallel with electrophysiology.
Sagnik Middya +7 more
wiley +1 more source
International Journal of Molecular Sciences, 2019 The blood-brain barrier (BBB) is a major functional barrier in the central nervous system (CNS), and inhibits the extravasation of intravascular contents and transports various essential nutrients between the blood and the brain.
S. Michinaga, Y. Koyama
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong +7 more
wiley +1 more source
Astrocyte molecular signatures in Huntington’s disease
Science Translational Medicine, 2019 Astrocyte gene expression is altered in mouse models of Huntington’s disease and in postmortem brain samples from patients with HD. A shared signature Huntington’s disease is a neurodegenerative disorder caused by a dominant mutation in the HTT gene ...
Blanca Díaz-Castro +4 more
semanticscholar +1 more source
Astrocytes in Flavivirus Infections [PDF]
International Journal of Molecular Sciences, 2019 Virus infections of the central nervous system (CNS) can manifest in various forms of inflammation, including that of the brain (encephalitis) and spinal cord (myelitis), all of which may have long-lasting deleterious consequences. Although the knowledge of how different viruses affect neural cells is increasing, understanding of the mechanisms by ...
Maja Potokar +2 more
openaire +4 more sources
Advanced Functional Materials, EarlyView.Glioblastoma multiforme is the most devastating and incurable brain tumor. To better study this disease, a 3D model is developed using a hyaluronic acid‐based hydrogel combined with a multicellular approach. This model recapitulates in vivo brain stiffness, cell‐extracellular matrix and cell‐cell interactions and the tumor's hijacking function with the
Mateo S. Andrade Mier +26 more
wiley +1 more source
Hemichannels: new roles in astroglial function
Frontiers in Physiology, 2014 The role of astrocytes in brain function has evolved over the last decade, from support cells to active participants in the neuronal synapse through the release of gliotransmitters.
Jimmy eStehberg, Juan Andrés Orellana
doaj +1 more source