Results 111 to 120 of about 194,703 (370)
Astrocytes mediate analogous memory in a multi-layer neuron-astrocytic network [PDF]
arXiv, 2021 Modeling the neuronal processes underlying short-term working memory remains the focus of many theoretical studies in neuroscience. Here we propose a mathematical model of spiking neuron network (SNN) demonstrating how a piece of information can be maintained as a robust activity pattern for several seconds then completely disappear if no other stimuli
arxiv
Redistribution of metabolic resources through astrocyte networks mitigates neurodegenerative stress
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Astrocytes respond to neuronal energy needs by mobilizing metabolic stores. How these resources are mobilized during neurodegeneration, especially in nearby regions that are not actively degenerating, could impact new therapeutic approaches.
Melissa L. Cooper +6 more
semanticscholar +1 more source
Amines, Astrocytes, and Arousal [PDF]
Neuron, 2017 Amine neurotransmitters, such as noradrenaline, mediate arousal, attention, and reward in the CNS. New data suggest that, from flies to mammals, a major mechanism for amine transmitter action is to raise astrocyte [Ca2+]i and release gliotransmitters that modulate neuronal activity and behavior.
Bazargani, N, Attwell, D
openaire +4 more sources
Advanced Healthcare Materials, EarlyView.Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray +2 more
wiley +1 more source
Breathing cluster in complex neuron-astrocyte networks [PDF]
arXiv, 2023 Brain activities are featured by spatially distributed neural clusters of coherent firings and a spontaneous switching of the clusters between the synchrony and asynchrony states. Evidences from {\it in vivo} experiments suggest that astrocytes, a type of glial cell regarded previously as providing only structural and metabolic supports to neurons ...
arxiv
Motor‐Free Soft Robots for Cancer Detection, Surgery, and In Situ Bioprinting
Advanced Healthcare Materials, EarlyView.Novel motor‐free soft robots for cancer detection, surgery, and in situ bioprinting–are presented. This master‐slave system is constructed from soft fibrous syringe architectures, removing the need for electrical motors and complex control mechanisms, while reducing the physical tremors.
Chi Cong Nguyen +17 more
wiley +1 more source
Bayesian inference and role of astrocytes in amyloid-beta dynamics with modelling of Alzheimer's disease using clinical data [PDF]
arXiv, 2023 Alzheimer's disease (AD) is a prominent, worldwide, age-related neurodegenerative disease that currently has no systemic treatment. Strong evidence suggests that permeable amyloid-beta peptide (Abeta) oligomers, astrogliosis and reactive astrocytosis cause neuronal damage in AD.
arxiv
Flexible 3D Kirigami Probes for In Vitro and In Vivo Neural Applications
Advanced Materials, EarlyView.A customizable and scalable approach to fabricate flexible 3D kirigami microelectrode arrays (MEAs) featuring up to 128 shanks, including surface and penetrating electrodes designed to interact with the 3D space of neural tissue, is presented. The 3D kirigami MEAs are successfully deployed in several neural applications, both in vitro and in vivo, and ...
Marie Jung +10 more
wiley +1 more source
Reactive astrocyte nomenclature, definitions, and future directions
Nature Neuroscience, 2021 C. Escartin +80 more
semanticscholar +1 more source
Single-nucleus RNA-seq identifies Huntington disease astrocyte states
Acta Neuropathologica Communications, 2019 Huntington Disease (HD) is an inherited movement disorder caused by expanded CAG repeats in the Huntingtin gene. We have used single nucleus RNASeq (snRNASeq) to uncover cellular phenotypes that change in the disease, investigating single cell gene ...
O. Al-Dalahmah +8 more
semanticscholar +1 more source