Results 131 to 140 of about 181,113 (262)

Metformin normalizes mitochondrial function to delay astrocyte senescence in a mouse model of Parkinson’s disease through Mfn2-cGAS signaling

open access: yesJournal of Neuroinflammation
Background Senescent astrocytes play crucial roles in age-associated neurodegenerative diseases, including Parkinson’s disease (PD). Metformin, a drug widely used for treating diabetes, exerts longevity effects and neuroprotective activities.
Min Wang   +8 more
doaj   +1 more source

Characterizing Learning in Spiking Neural Networks with Astrocyte-Like Units [PDF]

open access: yesarXiv
Traditional artificial neural networks take inspiration from biological networks, using layers of neuron-like nodes to pass information for processing. More realistic models include spiking in the neural network, capturing the electrical characteristics more closely.
arxiv  

Nanomaterials as therapeutic agents to modulate astrocyte-mediated inflammation in spinal cord injury

open access: yesMaterials Today Bio, 2023
Promoting the recovery of neurological function in patients with traumatic spinal cord injury (TSCI) remains challenging. The balance between astrocyte-mediated neurotrophic and pro-inflammatory responses is critical for TSCI repair.
Wenqi Luo   +10 more
doaj  

Astrocyte gene expression in Creutzfeldt-Jakob disease. [PDF]

open access: bronze, 1987
Laura Manuelidis   +3 more
openalex   +1 more source

Astrocyte-derived exosomal miR-378a-5p mitigates cerebral ischemic neuroinflammation by modulating NLRP3-mediated pyroptosis

open access: yesFrontiers in Immunology
ObjectiveThis study aimed to investigate the regulatory role of astrocyte-derived exosomes and their microRNAs (miRNAs) in modulating neuronal pyroptosis during cerebral ischemia.MethodsAstrocyte-derived exosomes were studied for treating cerebral ...
Ruiting Sun   +7 more
doaj   +1 more source

FDNet: Frequency Domain Denoising Network For Cell Segmentation in Astrocytes Derived From Induced Pluripotent Stem Cells [PDF]

open access: yesarXiv
Artificially generated induced pluripotent stem cells (iPSCs) from somatic cells play an important role for disease modeling and drug screening of neurodegenerative diseases. Astrocytes differentiated from iPSCs are important targets to investigate neuronal metabolism.
arxiv  

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