Results 231 to 240 of about 440,890 (382)

Artificial Intelligent‐Enhanced Metabolite Profiling for Intraoperative IDH1 Genotyping in Glioma Using an Orthogonally Responsive SERS Probe

Advanced Science, EarlyView.
This study presents a novel approach for intraoperative identification of the IDH1 genotype in glioma patients using a surface‐enhanced Raman scattering (SERS) probe to measure glutathione and hydrogen peroxide. By integrating AI‐driven deep learning algorithms, the method achieves rapid and accurate genotype differentiation, offering the potential to ...
Hang Yin, Xin Zhang, Zheng Zhao, Chong Cao, Minhua Xu, Suhongrui Zhou, Tian Xuan, Ziyi Jin, Limei Han, Yang Fan, Cong Wang, Xiao Zhu, Ying Mao, Jinhua Yu, Cong Li   +14 more
wiley   +1 more source

Ultracytochemical demonstration of alkaline phosphatase activity in astrocytes and subependymal cells in the rat brain.

, 1985
Shiro Mori, Mamoru Nagano
openalex   +2 more sources

Angiotensin II receptor subtypes are coupled with distinct signal-transduction mechanisms in neurons and astrocytes from rat brain. [PDF]

, 1991
Colin Sumners, Wei Tang, Blanka Železná, Mohan K. Raizada   +3 more
openalex   +1 more source

Mechanotransduction Activates Microglia and Impairs Phagocytosis in Stiff Amyloid‐β Plaques

Advanced Science, EarlyView.
The study constructs an in vitro Aβ plaque‐associated microglia model and uses SECM and SICM to in situ monitor changes in ROS levels, membrane permeability, and phagocytosis of microglia during Aβ clearance. It is found out that Aβ stiffness triggers microglial activation via the PIEZO1 mechanotransduction pathway, causing neuroinflammation and ...
Yulin Liu, Junjie Zhang, Yuxiang Zhao, Feixiang Fang, Siyu Zhang, Qiqi An, Jian Zhuang, Feng Xu, Fei Li   +8 more
wiley   +1 more source

Microglial control of astrocytes in response to microbial metabolites

Nature, 2018
Veit Rothhammer, Davis M. Borucki, Emily C. Tjon, M. Takenaka, C. Chao, A. Ardura-Fabregat, K. A. de Lima, Cristina Gutiérrez-Vázquez, Patrick Hewson, O. Staszewski, M. Blain, Luke M. Healy, T. Neziraj, Matilde Borio, Michael A. Wheeler, Loic Dragin, D. Laplaud, J. Antel, Jorge I Alvarez, M. Prinz, F. Quintana   +20 more
semanticscholar   +1 more source

Neuronal FGF13 Inhibits Mitochondria‐Derived Damage Signals to Prevent Neuroinflammation and Neurodegeneration in a Mouse Model of Parkinson's Disease

Advanced Science, EarlyView.
This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song, Xiangxu Wang, Luqing Ha, Lamei Hu, Shuyuan Mei, Yue Liang, Yujie Zhao, Xingyin Yang, Qingyu Zhang, Yuanzhang Zhou, Jianhua Ding, Yan Liu, Qigang Zhou, Feng Han, Gang Hu, Ming Lu   +15 more
wiley   +1 more source

Laminin is induced in astrocytes of adult brain by injury.

, 1984
P. Liesi, Seppo Kaakkola, D. Dahl, Antti Vaheri   +3 more
openalex   +1 more source

Inhibition of astrocyte proliferation and binding to brain tissue of anticardiolipin antibodies purified from lupus serum. [PDF]

, 1992
Kuang‐Hui Sun, W T Liu, Chang‐Youh Tsai, Tang-Shueen Liao, Whu-Mei Lin, Chia‐Li Yu   +5 more
openalex   +1 more source

DNase I‐Mediated Chemotactic Nanoparticles for NETs Targeting and Microenvironment Remodeling Treatment of Acute Ischemic Stroke

Advanced Science, EarlyView.
The neutrophil extracellular traps (NETs) play an important role in reperfusion injury in ischemic stroke. Here, considering the unique vascular localization of NETs, a DNase I‐mediated NETs‐targeting nanoparticle is developed to integrate the catalytic and chemotactic functions of DNase I and achieve the synergistic regulation of the internal and ...
Tongyu Zhang, Peixin Liu, Wenru Shen, Chao Li, Zhenhao Zhao, Yuxing Wu, Tao Sun, Chen Jiang   +7 more
wiley   +1 more source

Modeling neuroinflammatory interactions between microglia and astrocytes in a human iPSC-based coculture platform. [PDF]

Cell Commun Signal
Tujula I, Hyvärinen T, Lotila J, Rogal J, Voulgaris D, Sukki L, Tornberg K, Korpela K, Jäntti H, Malm T, Herland A, Kallio P, Narkilahti S, Hagman S.   +13 more
europepmc   +1 more source