Results 241 to 250 of about 462,755 (380)

LRRC8A is essential for swelling‐activated chloride current and for regulatory volume decrease in astrocytes

, 2018
Francesco Formaggio, Emanuela Saracino, Maria Grazia Mola, Shreyas Balachandra Rao, Mahmood Amiry‐Moghaddam, Michele Muccini, R. Zamboni, Grazia Paola Nicchia, Marco Caprini, Valentina Benfenati   +9 more
openalex   +2 more sources

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Astrocyte Biology in CNS Inflammatory Diseases: A Clinical-Translational Perspective. [PDF]

Neurol Neuroimmunol Neuroinflamm
Ye J, Quintana FJ.
europepmc   +1 more source

Integrated brain circuits: Neuron-astrocyte interaction in sleep-related rhythmogenesis

, 2010
Michael M. Halassa, Marco Dal Maschio, Riccardo Beltramo, Philip G. Haydon, Fabio Benfenati, Tommaso Fellin   +5 more
openalex   +2 more sources

Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes [PDF]

, 1991
J.F. Diedrich, Hal Minnigan, Richard I. Carp, John N. Whitaker, Richard Race, William H. Frey, Ashley T. Haase   +6 more
openalex   +1 more source

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

Advanced Science, EarlyView.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao, Jing Xi, Yuhao Sun, Yulan Li, Zhisheng Li, Wangjialu Lu, Jialu Chen, Lin Yang, Fan Fei, Heming Cheng, Li Cheng, Cenglin Xu, Zhuo Huang, Vladimir Parpura, Yi Wang, Zhong Chen   +15 more
wiley   +1 more source

Piezo1 induces Wnt7b⁺ astrocytes transformation to modulate glial scar stiffness and neuro-regeneration after stroke. [PDF]

Theranostics
Wu S, Hao W, Suo Q, Lu Q, Liu Z, Yao YQ, Shi R, Haroon K, Chen Y, Shao X, Wang Q, Li C, Xu Q, Li W, Tang Y, Yang GY, Zhang Z.   +16 more
europepmc   +1 more source

Neurotransmitter signaling in white matter [PDF]

, 2014
Butt, Arthur M., Fern, Robert F., Matute, Carlos   +2 more
core   +1 more source

Astrocytes in chronic pain and itch

Nature Reviews Neuroscience, 2019
R. Ji, C. Donnelly, M. Nedergaard
semanticscholar   +1 more source

Contribution of Microglia and Astrocytes to the Central Sensitization, Inflammatory and Neuropathic Pain in the Juvenile Rat [PDF]

, 2012
Hiroshi Ikeda, Takaki Kiritoshi, Kazuyuki Murase   +2 more
openalex   +1 more source