Results 21 to 30 of about 249,621 (311)

Exocytosis of ATP from astrocytes modulates phasic and tonic inhibition in the neocortex [PDF]

, 2014
Communication between neuronal and glial cells is important for many brain functions. Astrocytes can modulate synaptic strength via Ca2+-stimulated release of various gliotransmitters, including glutamate and ATP. A physiological role of ATP release from
Lalo, Ulyana, Pankratov, Yuriy, Palygin, Oleg, Oleg Palygin (407627), Philip G Haydon, Ulyana Lalo (506296), Yuriy Pankratov, Seyed Rasooli-Nejad (506297), Rasooli-Nejad, Seyed, Yuriy Pankratov (407630), Oleg Palygin, Ulyana Lalo, Haydon, Philip G., Jemma Andrew, Jemma Andrew (506298), Philip G. Haydon (506299), Andrew, Jemma, Seyed Rasooli-Nejad   +17 more
core   +1 more source

Astrocytes and Aging [PDF]

Frontiers in Aging Neuroscience, 2018
By 2050, the aging population is predicted to expand by over 100%. Considering this rapid growth, and the additional strain it will place on healthcare resources because of age-related impairments, it is vital that researchers gain a deeper understanding of the cellular interactions that occur with normal aging.
Alexandra L. Palmer, Shalina S. Ousman, Shalina S. Ousman   +2 more
openaire   +3 more sources

P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes [PDF]

, 2008
ATP plays an important role in signal transduction between neuronal and glial circuits and within glial networks. Here we describe currents activated by ATP in astrocytes acutely isolated from cortical brain slices by non-enzymatic mechanical ...
Lalo, Ulyana, Pankratov, Yuriy, Verkhratsky, A. N. (Alekseĭ Nestorovich), Wichert, S., Kirchhoff, F., Rossner, Moritz J., Verkhratsky, Alexei; id_orcid, Kirchhoff, Frank, Verkhratsky, Alexei, Pankratov, Y., Rossner, M., Lalo, U., Verkhratskiĭ, A. N. (Alekseĭ Nestorovich), North, R., Pankratov, Yuri, North, R. Alan, Verkhratsky, A., Wichert, Sven P.   +17 more
core   +1 more source

Astrocytes from cortex and striatum show differential responses to mitochondrial toxin and BDNF: implications for protection of striatal neurons expressing mutant huntingtin

Journal of Neuroinflammation, 2020
Background Evidence shows significant heterogeneity in astrocyte gene expression and function. We previously demonstrated that brain-derived neurotrophic factor (BDNF) exerts protective effects on whole brain primary cultured rat astrocytes treated with ...
Julieta Saba, Federico López Couselo, Juan Turati, Lila Carniglia, Daniela Durand, Andrea de Laurentiis, Mercedes Lasaga, Carla Caruso   +7 more
doaj   +1 more source

Morinda officinalis oligosaccharides mitigate depression-like behaviors in hypertension rats by regulating Mfn2-mediated mitophagy

Journal of Neuroinflammation, 2023
Objective Patients with hypertension have a risk of depression. Morinda officinalis oligosaccharides (MOOs) have anti-depressant properties. In this study, we aimed to determine whether MOOs can improve the symptoms of depression in individuals with ...
Lixuan Yang, Yutian Ao, Yannan Li, Baoan Dai, Jingchun Li, Wenzhe Duan, Wei Gao, Zhonghui Zhao, Zhenyun Han, Rongjuan Guo   +9 more
doaj   +1 more source

Astrocytes in the Amygdala

The FASEB Journal, 2010
The amygdala is connected to numerous brain regions and is involved in complex behaviors such as survival and reproduction. This highly conserved brain region is sexually dimorphic in several species with the most dramatic differences found in the medial subregion.
Ryan T, Johnson, S Marc, Breedlove, Cynthia L, Jordan   +2 more
openaire   +2 more sources

Porosome in astrocytes [PDF]

Journal of Cellular and Molecular Medicine, 2009
AbstractSecretion is a universal cellular process occurring in bakers yeast, to the complex multicellular organisms, to humans beings. Neurotransmission, digestion, immune response or the release of hormones occur as a result of cell secretion. Secretory defects result in numerous diseases and hence a molecular understanding of the process is critical.
Lee, Jin-Sook, Cho, Won Jin, Jeftinija, Ksenija, Jeftinija, Srdija, Jena, Bhanu P   +4 more
openaire   +2 more sources

Olig2-astrocytes express neutral amino acid transporter SLC7A10 (Asc-1) in the adult brain

Molecular Brain, 2021
We have reported that the transcription factor Olig2 labels a subpopulation of astrocytes (Olig2-astrocytes), which show distribution patterns different from those of GFAP-expressing astrocytes (GFAP-astrocytes) in the adult brain.
Kouko Tatsumi, Kaoru Kinugawa, Ayami Isonishi, Masahiro Kitabatake, Hiroaki Okuda, Shoko Takemura, Tatsuhide Tanaka, Eiichiro Mori, Akio Wanaka   +8 more
doaj   +1 more source

Morphological and physiological interactions of NG2-glia with astrocytes and neurons [PDF]

, 2007
Models of central nervous system (CNS) function have historically been based on neurons and their synaptic contacts - the neuronal doctrine. This doctrine envisages glia as passive supportive cells.
Hamilton, N., Wigley, R., Nishiyama, Akiko, Kirchhoff, F., Wigley, Rebekah, Butt, Arthur M., Hamilton, Niki, Kirchhoff, Frank, Nishiyama, A., Butt, Arthur, Hamilton, Niki; id_orcid, Butt, A., Wigley, Becky   +12 more
core   +1 more source

Stabilization of the retinal vascular network by reciprocal feedback between blood vessels and astrocytes [PDF]

, 2005
Development of the retinal vasculature is controlled by a hierarchy of interactions among retinal neurons, astrocytes and blood vessels. Retinal neurons release platelet-derived growth factor (PDGFA) to stimulate proliferation of astrocytes, which in ...
Heloise West, Richardson, WD, West, H, William D. Richardson, Fruttiger, M, Marcus Fruttiger   +5 more
core   +1 more source