Results 21 to 30 of about 202,723 (265)

Astrocytes in the Amygdala

open access: yesThe FASEB Journal, 2010
The amygdala is connected to numerous brain regions and is involved in complex behaviors such as survival and reproduction. This highly conserved brain region is sexually dimorphic in several species with the most dramatic differences found in the medial subregion.
Ryan T, Johnson   +2 more
openaire   +2 more sources

Olig2-astrocytes express neutral amino acid transporter SLC7A10 (Asc-1) in the adult brain

open access: yesMolecular Brain, 2021
We have reported that the transcription factor Olig2 labels a subpopulation of astrocytes (Olig2-astrocytes), which show distribution patterns different from those of GFAP-expressing astrocytes (GFAP-astrocytes) in the adult brain.
Kouko Tatsumi   +8 more
doaj   +1 more source

Morinda officinalis oligosaccharides mitigate depression-like behaviors in hypertension rats by regulating Mfn2-mediated mitophagy

open access: yesJournal of Neuroinflammation, 2023
Objective Patients with hypertension have a risk of depression. Morinda officinalis oligosaccharides (MOOs) have anti-depressant properties. In this study, we aimed to determine whether MOOs can improve the symptoms of depression in individuals with ...
Lixuan Yang   +9 more
doaj   +1 more source

Astrocytes and Aging [PDF]

open access: yesFrontiers in Aging Neuroscience, 2018
By 2050, the aging population is predicted to expand by over 100%. Considering this rapid growth, and the additional strain it will place on healthcare resources because of age-related impairments, it is vital that researchers gain a deeper understanding of the cellular interactions that occur with normal aging.
Alexandra L. Palmer   +2 more
openaire   +3 more sources

An update on reactive astrocytes in chronic pain

open access: yesJournal of Neuroinflammation, 2019
Chronic pain is a critical clinical problem with an increasing prevalence. However, there are limited effective prevention measures and treatments for chronic pain.
Ting Li   +4 more
doaj   +1 more source

Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes

open access: yesCell Reports, 2016
Growing evidence indicates important roles for astrocytes in neurodevelopment and diseases. However, astrocytes and their roles in these processes remain poorly understood.
E Tian   +7 more
doaj   +1 more source

Alterations of gene expression and glutamate clearance in astrocytes derived from an MeCP2-null mouse model of Rett syndrome. [PDF]

open access: yesPLoS ONE, 2012
Rett syndrome (RTT) is a neurodevelopmetal disorder associated with mutations in the methyl-CpG-binding protein 2 (MeCP2) gene. MeCP2-deficient mice recapitulate the neurological degeneration observed in RTT patients.
Yasunori Okabe   +5 more
doaj   +1 more source

Extracellular Neuroleukin Enhances Neuroleukin Secretion From Astrocytes and Promotes Axonal Growth in vitro and in vivo

open access: yesFrontiers in Pharmacology, 2018
Under pathological conditions in the central nervous system (CNS), including spinal cord injury, astrocytes show detrimental effects against neurons.
Yoshitaka Tanie   +3 more
doaj   +1 more source

β-lactolin, a Monoamine Oxidase B Inhibitory Lactopeptide, Suppresses Reactive Oxygen Species Production in Lipopolysaccharide-Stimulated Astrocytes

open access: yesApplied Sciences, 2021
Astrocytes are known to regulate normal brain function. Monoamine oxidase B (MAO-B), an enzyme highly expressed in astrocytes, metabolizes dopamine (DA) and induces reactive oxygen species (ROS) production.
Shiori Akiyama   +4 more
doaj   +1 more source

Gene expression profiles of reactive astrocytes cultured from dopamine-depleted striatum

open access: yesNeurobiology of Disease, 2005
We have carried out cDNA array analysis in order to characterize the gene expression profiles of reactive astrocytes from dopamine-depleted striatum.
Takao Nakagawa   +2 more
doaj   +1 more source

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