Results 31 to 40 of about 273,908 (305)
Background Evidence shows significant heterogeneity in astrocyte gene expression and function. We previously demonstrated that brain-derived neurotrophic factor (BDNF) exerts protective effects on whole brain primary cultured rat astrocytes treated with ...
Julieta Saba +7 more
doaj +1 more source
Olig2-astrocytes express neutral amino acid transporter SLC7A10 (Asc-1) in the adult brain
We have reported that the transcription factor Olig2 labels a subpopulation of astrocytes (Olig2-astrocytes), which show distribution patterns different from those of GFAP-expressing astrocytes (GFAP-astrocytes) in the adult brain.
Kouko Tatsumi +8 more
doaj +1 more source
Stabilization of the retinal vascular network by reciprocal feedback between blood vessels and astrocytes [PDF]
Development of the retinal vasculature is controlled by a hierarchy of interactions among retinal neurons, astrocytes and blood vessels. Retinal neurons release platelet-derived growth factor (PDGFA) to stimulate proliferation of astrocytes, which in ...
Heloise West +5 more
core +1 more source
Objective Patients with hypertension have a risk of depression. Morinda officinalis oligosaccharides (MOOs) have anti-depressant properties. In this study, we aimed to determine whether MOOs can improve the symptoms of depression in individuals with ...
Lixuan Yang +9 more
doaj +1 more source
Differential sensitivity of brainstem vs cortical astrocytes to changes in pH reveals functional regional specialization of astroglia [PDF]
Astrocytes might function as brain interoceptors capable of detecting different (chemo)sensory modalities and transmitting sensory information to the relevant neural networks controlling vital functions.
Kasimov, V +6 more
core +1 more source
Morphological and physiological interactions of NG2-glia with astrocytes and neurons [PDF]
Models of central nervous system (CNS) function have historically been based on neurons and their synaptic contacts - the neuronal doctrine. This doctrine envisages glia as passive supportive cells.
Hamilton, N. +12 more
core +1 more source
Astrocytes-hNS1 are permissible and susceptible to ZIKV infection.
(A) The astrocytes-hNS1 were seeded in 24-well plates and processed for immunofluorescence with antibodies against GFAP (green) and ZIKV envelope protein (red), and the nuclei were stained with Hoechst (blue). Scale bar 50 μm.
Edson Iván Rubio-Hernández (14856891) +5 more
core +1 more source
TGF-beta(2)- and H2O2-Induced Biological Changes in Optic Nerve Head Astrocytes Are Reduced by the Antioxidant Alpha-Lipoic Acid [PDF]
Background/Aims: The goal of the present study was to determine whether transforming growth factor-beta(2) (TGF-beta(2))- and oxidative stress-induced cellular changes in cultured human optic nerve head (ONH) astrocytes could be reduced by pretreatment ...
Yu, Alice L. +2 more
core +1 more source
AbstractSecretion is a universal cellular process occurring in bakers yeast, to the complex multicellular organisms, to humans beings. Neurotransmission, digestion, immune response or the release of hormones occur as a result of cell secretion. Secretory defects result in numerous diseases and hence a molecular understanding of the process is critical.
Lee, Jin-Sook +4 more
openaire +2 more sources
Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes
Growing evidence indicates important roles for astrocytes in neurodevelopment and diseases. However, astrocytes and their roles in these processes remain poorly understood.
E Tian +7 more
doaj +1 more source

