Results 41 to 50 of about 273,908 (305)
An update on reactive astrocytes in chronic pain
Journal of Neuroinflammation, 2019 Chronic pain is a critical clinical problem with an increasing prevalence. However, there are limited effective prevention measures and treatments for chronic pain.
Ting Li +4 more
doaj +1 more source
Mecanismes moleculars implicats en la secreció de pèptids en cèl•lules glials del sistema nerviós central [PDF]
, 2011 [cat] En els últims anys, diversos treballs han demostrat que els astròcits participen activament en el desenvolupament i la plasticitat del sistema nerviós central, així com en la modulació de la neurotransmissió.
Paco Mercader, Sonia
core +4 more sources
Frontiers in Pharmacology, 2018 Under pathological conditions in the central nervous system (CNS), including spinal cord injury, astrocytes show detrimental effects against neurons.
Yoshitaka Tanie +3 more
doaj +1 more source
Alterations of gene expression and glutamate clearance in astrocytes derived from an MeCP2-null mouse model of Rett syndrome. [PDF]
PLoS ONE, 2012 Rett syndrome (RTT) is a neurodevelopmetal disorder associated with mutations in the methyl-CpG-binding protein 2 (MeCP2) gene. MeCP2-deficient mice recapitulate the neurological degeneration observed in RTT patients.
Yasunori Okabe +5 more
doaj +1 more source
Applied Sciences, 2021 Astrocytes are known to regulate normal brain function. Monoamine oxidase B (MAO-B), an enzyme highly expressed in astrocytes, metabolizes dopamine (DA) and induces reactive oxygen species (ROS) production.
Shiori Akiyama +4 more
doaj +1 more source
Gene expression profiles of reactive astrocytes cultured from dopamine-depleted striatum
Neurobiology of Disease, 2005 We have carried out cDNA array analysis in order to characterize the gene expression profiles of reactive astrocytes from dopamine-depleted striatum.
Takao Nakagawa +2 more
doaj +1 more source
FGF/heparin differentially regulates Schwann cell and olfactory ensheathing cell interactions with astrocytes: a role in astrocytosis [PDF]
, 2007 After injury, the CNS undergoes an astrocyte stress response characterized by reactive astrocytosis/proliferation, boundary formation, and increased glial fibrillary acidic protein (GFAP) and chondroitin sulfate proteoglycan (CSPG) expression. Previously,
Fairless, R. +15 more
core +1 more source
Astrocytes, emerging stars of energy homeostasis [PDF]
, 2018 Astrocytes have historically been considered structural supporting cells for neurons. Thanks to new molecular tools, allowing specific cell ablation or over-expression of genes, new unexpected astrocytic functions have recently been unveiled. This review
Simonetta Camandola
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Frontiers in Aging Neuroscience, 2018 By 2050, the aging population is predicted to expand by over 100%. Considering this rapid growth, and the additional strain it will place on healthcare resources because of age-related impairments, it is vital that researchers gain a deeper understanding of the cellular interactions that occur with normal aging.
Alexandra L. Palmer +2 more
openaire +3 more sources
Fast Generation of Functional Subtype Astrocytes from Human Pluripotent Stem Cells
Stem Cell Reports, 2018 Summary: Differentiation of astrocytes from human pluripotent stem cells (hPSCs) is a tedious and variable process. This hampers the study of hPSC-generated astrocytes in disease processes and drug development.
Xiang Li +13 more
doaj +1 more source