Results 11 to 20 of about 249,621 (311)
Copper Metabolism of Astrocytes [PDF]
Frontiers in Aging Neuroscience, 2013 This short review will summarize the current knowledge on the uptake, storage and export of copper ions by astrocytes and will address the potential roles of astrocytes in copper homeostasis in the normal and diseased brain.
Ralf eDringen +2 more
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Astrocytes in Tauopathies [PDF]
Frontiers in Neurology, 2020 Tauopathies are a group of neurodegenerative diseases characterized by the progressive accumulation across the brain of hyperphosphorylated aggregates of the microtubule-associated protein tau that vary in isoform composition, structural conformation and localization.
Reid, Matt +4 more
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Astrocytes-hNS1 are a pure culture of human astrocytes. [PDF]
, 2023 hNS-1 cells were differentiated for 21 days. The differentiated cells were harvested and seeded in culture labware without poly-L-lysine treatment and with DMEM.
Edson Iván Rubio-Hernández (14856891) +5 more
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Exocytosis in Astrocytes [PDF]
Biomolecules, 2021 Until recently, astrocytes were thought to be a part of a simple “brain glue” providing only a supporting role for neurons. However, the discoveries of the last two decades have proven astrocytes to be dynamic partners participating in brain metabolism and actively influencing communication between neurons.
Aleksandra Mielnicka, Piotr Michaluk
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Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis [PDF]
Nature, 2017 Astrocytes are complex glial cells with numerous fine cellular processes that infiltrate the neuropil and interact with synapses. The mechanisms that control the establishment of astrocyte morphology are unknown, and it is unclear whether impairing astrocytic infiltration of the neuropil alters synaptic connectivity.
Stogsdill, Jeff A. +8 more
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The Synucleins and the Astrocyte
Biology, 2023 Synucleins consist of three proteins exclusively expressed in vertebrates. α-Synuclein (αS) has been identified as the main proteinaceous aggregate in Lewy bodies, a pathological hallmark of many neurodegenerative diseases. Less is understood about β-synuclein (βS) and γ-synuclein (γS), although it is known βS can interact with αS in vivo to inhibit ...
Abigail J. Myers +3 more
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Neurotherapeutics, 2010 Astrocytes form a significant constituent of seizure foci in the human brain. For a long time it was believed that astrocytes play a significant role in the causation of seizures. With the increase in our understanding of the unique biology of these cells, their precise role in seizure foci is receiving renewed attention.
Nihal C, de Lanerolle +2 more
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Astrocytes in schizophrenia [PDF]
Brain and Neuroscience Advances, 2021 Schizophrenia is a severe and clinically heterogenous mental disorder affecting approximately 1% of the population worldwide. Despite tremendous achievements in the field of schizophrenia research, its precise aetiology remains elusive. Besides dysfunctional neuronal signalling, the pathophysiology of schizophrenia appears to involve molecular and ...
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Astrocytes-hNS1 are permissible and susceptible to ZIKV infection. [PDF]
, 2023 (A) The astrocytes-hNS1 were seeded in 24-well plates and processed for immunofluorescence with antibodies against GFAP (green) and ZIKV envelope protein (red), and the nuclei were stained with Hoechst (blue). Scale bar 50 μm.
Edson Iván Rubio-Hernández (14856891) +5 more
core +1 more source
Progress in Neurobiology, 2008 Neurons have long held the spotlight as the central players of the nervous system, but we must remember that we have equal numbers of astrocytes and neurons in the brain. Are these cells only filling up the space and passively nurturing the neurons, or do they also contribute to information transfer and processing?
Doris D, Wang, Angélique, Bordey
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