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Journal of Experimental & Clinical Cancer Research, 2017 Background The prognosis of human astrocytoma is poor, and the molecular alterations underlying its pathogenesis still needed to be elucidated. Nucleolar and spindle associated protein 1 (NUSAP1) was observed in several types of cancers, but its role in ...
Xianqiu Wu +11 more
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Expression of P53 and Ki-67 in Different Grades of Astrocytomas [PDF]
International Journal of Medical Arts, 2022 Background: Astrocytomas are considered the most prevalent central nervous system [CNS] tumors. Diffuse astrocytomas are evaluated by a three-tiered system [II, III, and IV] according to the 2007 WHO classification. The WHO grading scheme is based on the
Rania Rifat Abdel-Maqsoud Mohamed +1 more
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BMC Cancer, 2021 Background Astrocytoma is a common type of central nervous system tumor. In this study, we investigated the correlation between ST6GAL1 and CYP19A1 polymorphisms and the risk and prognosis of astrocytoma.
Tuo Wang +6 more
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Inhibition of STAT3 reduces astrocytoma cell invasion and constitutive activation of STAT3 predicts poor prognosis in human astrocytoma. [PDF]
PLoS ONE, 2013 Astrocytoma cells characteristically possess high invasion potentials. Recent studies have revealed that knockdown of signal transducers and activators of transcription 3 (STAT3) expression by RNAi induces apoptosis in astrocytoma cell. Nevertheless, the
Qinchuan Liang +4 more
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Frontiers in Oncology, 2021 The pro-oncogene ETS-1 (E26 transformation-specific sequence 1) is a key regulator of the proliferation and invasion of cancer cells. The present work examined the correlation of the aberrant expression of ETS-1 with histological or clinical ...
Junping Wang +6 more
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Glutamate Signaling and Filopodiagenesis of Astrocytoma Cells in Brain Cancers: Survey and Questions
Cells, 2022 Astrocytes are non-excitable cells in the CNS that can cause life-threatening astrocytoma tumors when they transform to cancerous cells. Perturbed homeostasis of the neurotransmitter glutamate is associated with astrocytoma tumor onset and progression ...
Mitra Tabatabaee, Frederic Menard
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A 16-gene signature distinguishes anaplastic astrocytoma from glioblastoma. [PDF]
PLoS ONE, 2014 Anaplastic astrocytoma (AA; Grade III) and glioblastoma (GBM; Grade IV) are diffusely infiltrating tumors and are called malignant astrocytomas. The treatment regimen and prognosis are distinctly different between anaplastic astrocytoma and glioblastoma ...
Soumya Alige Mahabala Rao +9 more
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Cancer Medicine, 2023 Background The latest fifth edition of the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (WHO CNS 5 classification) released in 2021 defined astrocytoma, IDH‐mutant, Grade 4.
Wenlin Chen +21 more
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CNS Oncology, 2016 Anaplastic astrocytoma (AA) is a diffusely infiltrating, malignant, astrocytic, primary brain tumor. AA is currently defined by histology although future classification schemes will include molecular alterations. AA can be separated into subgroups, which share similar molecular profiles, age at diagnosis and median survival, based on 1p/19q co-deletion
Sean A, Grimm, Marc C, Chamberlain
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BMJ Case Reports, 2016 Pilocytic astrocytoma (PA) is a benign tumour of childhood, often located in deep midline structures such as the brainstem and the cerebellum.1 Gross surgical resection is curative in the majority of patients.2 We report a case of recurrent PA diagnosed after an acute confusional state and rightsided spastic hemiparesis in a previously healthy 38-year ...
Lourenço, Eva Patrícia +3 more
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