Results 1 to 10 of about 109,064 (360)

Nucleolar and spindle associated protein 1 promotes the aggressiveness of astrocytoma by activating the Hedgehog signaling pathway

open access: yesJournal of Experimental & Clinical Cancer Research, 2017
Background The prognosis of human astrocytoma is poor, and the molecular alterations underlying its pathogenesis still needed to be elucidated. Nucleolar and spindle associated protein 1 (NUSAP1) was observed in several types of cancers, but its role in ...
Xianqiu Wu   +11 more
doaj   +2 more sources

Anaplastic Astrocytoma

open access: yesCurrent Treatment Options in Neurology, 2020
Opinion statementStandard treatment of anaplastic astrocytoma (AA) in good performance patients consists of maximal safe surgical resection followed by focal, fractionated, external beam radiotherapy (RT) alone or in combination with concurrent and ...
S. Grimm, Thomas J. Pfiffner
semanticscholar   +4 more sources

Ependymal astrocytoma: subependyoma or subependymal glomerate astrocytoma [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 1982
The histological study of four cases and one by electron microscopy of subependyomomas allowed us to obtain morphostructural characteristics of ependymocytes and astrocytes.
Francisco Duarte   +4 more
doaj   +5 more sources

Pilomyxoid astrocytoma of the brainstem

open access: yesRare Tumors, 2013
A pilomyxoid astrocytoma is a recently described tumor that occurs predominantly in the hypothalamic-chiasmatic region and is rarely found elsewhere. It has similar features as pilocytic astrocytomas, but has distinct histological characteristics and a ...
Marco Antonio Zanini   +6 more
doaj   +5 more sources

Expression of P53 and Ki-67 in Different Grades of Astrocytomas [PDF]

open access: yesInternational Journal of Medical Arts, 2022
Background: Astrocytomas are considered the most prevalent central nervous system [CNS] tumors. Diffuse astrocytomas are evaluated by a three-tiered system [II, III, and IV] according to the 2007 WHO classification. The WHO grading scheme is based on the
Rania Rifat Abdel-Maqsoud Mohamed   +1 more
doaj   +1 more source

Association of ST6GAL1 and CYP19A1 polymorphisms in the 3′-UTR with astrocytoma risk and prognosis in a Chinese Han population

open access: yesBMC Cancer, 2021
Background Astrocytoma is a common type of central nervous system tumor. In this study, we investigated the correlation between ST6GAL1 and CYP19A1 polymorphisms and the risk and prognosis of astrocytoma.
Tuo Wang   +6 more
doaj   +1 more source

Inhibition of STAT3 reduces astrocytoma cell invasion and constitutive activation of STAT3 predicts poor prognosis in human astrocytoma. [PDF]

open access: yesPLoS ONE, 2013
Astrocytoma cells characteristically possess high invasion potentials. Recent studies have revealed that knockdown of signal transducers and activators of transcription 3 (STAT3) expression by RNAi induces apoptosis in astrocytoma cell. Nevertheless, the
Qinchuan Liang   +4 more
doaj   +1 more source

Hypermethylation of the Promoter of miR-338-5p Mediates Aberrant Expression of ETS-1 and Is Correlated With Disease Severity Of Astrocytoma Patients

open access: yesFrontiers in Oncology, 2021
The pro-oncogene ETS-1 (E26 transformation-specific sequence 1) is a key regulator of the proliferation and invasion of cancer cells. The present work examined the correlation of the aberrant expression of ETS-1 with histological or clinical ...
Junping Wang   +6 more
doaj   +1 more source

Glutamate Signaling and Filopodiagenesis of Astrocytoma Cells in Brain Cancers: Survey and Questions

open access: yesCells, 2022
Astrocytes are non-excitable cells in the CNS that can cause life-threatening astrocytoma tumors when they transform to cancerous cells. Perturbed homeostasis of the neurotransmitter glutamate is associated with astrocytoma tumor onset and progression ...
Mitra Tabatabaee, Frederic Menard
doaj   +1 more source

A 16-gene signature distinguishes anaplastic astrocytoma from glioblastoma. [PDF]

open access: yesPLoS ONE, 2014
Anaplastic astrocytoma (AA; Grade III) and glioblastoma (GBM; Grade IV) are diffusely infiltrating tumors and are called malignant astrocytomas. The treatment regimen and prognosis are distinctly different between anaplastic astrocytoma and glioblastoma ...
Soumya Alige Mahabala Rao   +9 more
doaj   +1 more source

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