Validation of Soft Classification Models using Partial Class Memberships: An Extended Concept of Sensitivity & Co. applied to the Grading of Astrocytoma Tissues [PDF]
Chemometrics and Intelligent Laboratory Systems, 122 (2013), 12 -
22, 2013 We use partial class memberships in soft classification to model uncertain labelling and mixtures of classes. Partial class memberships are not restricted to predictions, but may also occur in reference labels (ground truth, gold standard diagnosis) for training and validation data.
Beleites, Claudia +2 more
arxiv +3 more sources
Infratentorial IDH-mutant astrocytoma is a distinct subtype
Acta Neuropathologica, 2020 Diffuse IDH-mutant astrocytic tumors are rarely diagnosed in the cerebellum or brainstem. In this multi-institutional study, we characterized a series of primary infratentorial IDH-mutant astrocytic tumors with respect to clinical and molecular ...
Rouzbeh Banan +26 more
semanticscholar +1 more source
Cancer Medicine, 2023 Background The latest fifth edition of the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (WHO CNS 5 classification) released in 2021 defined astrocytoma, IDH‐mutant, Grade 4.
Wenlin Chen +21 more
doaj +1 more source
Astrocytoma: A Hormone-Sensitive Tumor?
International Journal of Molecular Sciences, 2020 Astrocytomas and, in particular, their most severe form, glioblastoma, are the most aggressive primary brain tumors and those with the poorest vital prognosis. Standard treatment only slightly improves patient survival.
A. Hirtz +3 more
semanticscholar +1 more source
Detection of Glioma-Related Hotspot Mutations Through Sequencing of Cerebrospinal Fluid (CSF)-Derived Circulating Tumor DNA: A Pilot Study on CSF-Based Liquid Biopsy for Primary Spinal Cord Astrocytoma [PDF]
Neurospine, 2023 Objective Although cerebrospinal fluid (CSF)-based liquid biopsy was proved to be practical in molecular analysis of intracranial gliomas, liquid biopsy of primary intramedullary astrocytoma was rarely reported.
Lei Cheng +9 more
doaj +1 more source
BMJ Case Reports, 2016 Pilocytic astrocytoma (PA) is a benign tumour of childhood, often located in deep midline structures such as the brainstem and the cerebellum.1 Gross surgical resection is curative in the majority of patients.2 We report a case of recurrent PA diagnosed after an acute confusional state and rightsided spastic hemiparesis in a previously healthy 38-year ...
Lourenço, Eva Patrícia +3 more
openaire +3 more sources
Machine Learning Decision Tree Models for Differentiation of Posterior Fossa Tumors Using Diffusion Histogram Analysis and Structural MRI Findings. [PDF]
, 2020 We applied machine learning algorithms for differentiation of posterior fossa tumors using apparent diffusion coefficient (ADC) histogram analysis and structural MRI findings.
Aboian, Mariam +3 more
core +1 more source
Acta Neuropathologica Communications, 2023 In IDH-mutant astrocytoma, IDH2 mutation is quite rare and biological mechanisms underlying tumor progression in IDH2-mutant astrocytoma remain elusive.
Kensuke Tateishi +15 more
doaj +1 more source
SNHG17 drives malignant behaviors in astrocytoma by targeting miR-876-5p/ERLIN2 axis
BMC Cancer, 2020 Background Astrocytoma is a common tumor type in primary central nervous system and has a high death rate around the world. Aberrant expression of long non-coding RNAs (lncRNAs) has been introduced by emerging studies to result in the development of ...
Fengping Du, Qian Hou
doaj +1 more source
Distinct aneuploid evolution of astrocytoma and glioblastoma during recurrence
npj Precision Oncology, 2023 Astrocytoma and glioblastoma (GB) are reclassified subtypes of adult diffuse gliomas based on distinct isocitrate dehydrogenase (IDH) mutation in the fifth edition of the WHO Classification of Tumors of the Central Nervous System.
Jinsen Zhang +16 more
doaj +1 more source