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Cancer Reports, 2023 Background A form of cancer called astrocytoma can develop in the brain or spinal cord and sometimes causes death. A detailed overview of the precise signaling cascade underlying astrocytoma formation has not yet been revealed, although various factors ...
Chowdhury Lutfun Nahar Metu +8 more
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Crossed Aphasia in a Patient with Anaplastic Astrocytoma of the Non-Dominant Hemisphere [PDF]
, 2017 Aphasia describes a spectrum of speech impairments due to damage in the language centers of the brain. Insult to the inferior frontal gyrus of the dominant cerebral hemisphere results in Broca\u27s aphasia - the inability to produce fluent speech.
Anand, Neil +3 more
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, 2016 Pilocytic astrocytoma (PA) is the most common pediatric brain tumor in children. PAs are a distinct histologic and biologic subset of glioma that have a slow growth rate and may even spontaneously regress. These tumors tend to arise in the cerebellum and chiasmatic/hypothalamic region, but can also occur in other regions of the central nervous system ...
Miriam, Bornhorst +2 more
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Journal of Biomedical Science, 2012 Background Astrocytomas are cancers of the brain in which high levels of extracellular glutamate plays a critical role in tumor growth and resistance to conventional treatments.
Varini Karine +6 more
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Immunocompetent murine models for the study of glioblastoma immunotherapy. [PDF]
, 2014 Glioblastoma remains a lethal diagnosis with a 5-year survival rate of less than 10%. (NEJM 352:987-96, 2005) Although immunotherapy-based approaches are capable of inducing detectable immune responses against tumor-specific antigens, improvements in ...
Bloch, Orin +9 more
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Recurrent Optic Nerve Pilocytic Astrocytoma: A Rare Case [PDF]
Journal of Clinical and Diagnostic Research, 2017 Pilocytic astrocytoma is a low grade glioma that affects mostly children and young adults and can occur anywhere in the central nervous system. Pilocytic astrocytoma of the optic nerve is an equally indolent subtype that is often associated with ...
SUDHA GIRISH MENON +3 more
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A rare, pediatric, fourth-ventricular, anaplastic astrocytoma
Radiology Case Reports, 2021 Anaplastic astrocytoma, a diffusely infiltrating, malignant, astrocytic, primary brain tumor, is most commonly observed between 30 and 50 years of age. Anaplastic astrocytomas are now classified as WHO grade III lesions, with imaging characteristics and ...
Dang Vinh Hiep, MD, PhD +2 more
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Genetic alterations in gliosarcoma and giant cell glioblastoma [PDF]
, 2015 The majority of glioblastomas develop rapidly with a short clinical history (primary glioblastoma IDH wild-type), whereas secondary glioblastomas progress from diffuse astrocytoma or anaplastic astrocytoma.
ANTONELLI, MANILA +13 more
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Transcriptome analysis reveals distinct gene expression profiles in astrocytoma grades II-IV
Biomedical Papers, 2017 Background: Astrocytoma is the most prevalent form of primary brain cancer categorized into four histological grades by the World Health Organization. Investigation into individual grades of astrocytoma by previous studies has provided some insight into ...
Nato Narsia +3 more
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Morphological analysis of CDC2 and glycogen synthase kinase 3β phosphorylation as markers of g2 → m transition in glioma. [PDF]
, 2011 G2 → M transition is a strategic target for glioma chemotherapy. Key players in G2 → M transition include CDC2 and glycogen synthase kinase 3β (GSK3β), which are highly regulated by posttranslational phosphorylation.
Otero, José Javier, Tihan, Tarik
core +3 more sources