Results 31 to 40 of about 109,064 (360)
Brain tumour genetic network signatures of survival [PDF]
, 2023 Tumour heterogeneity is increasingly recognized as a major obstacle to therapeutic success across neuro-oncology. Gliomas are characterised by distinct combinations of genetic and epigenetic alterations, resulting in complex interactions across multiple molecular pathways.
arxiv +1 more source
BMC Cancer, 2004 Background Astrocytoma is a common aggressive intracranial tumor and presents a formidable challenge in the clinic. Association of altered DNA methylation patterns of the promoter CpG islands with the expression profile of cancer-related genes, has been ...
Wang Yifei +7 more
doaj +1 more source
Total copy number variation as a prognostic factor in adult astrocytoma subtypes
Acta Neuropathologica Communications, 2019 Since the discovery that IDH1/2 mutations confer a significantly better prognosis in astrocytomas, much work has been done to identify other molecular signatures to help further stratify lower-grade astrocytomas and glioblastomas, with the goal of ...
K. Mirchia +10 more
semanticscholar +1 more source
Phytochemical study and evaluation of the cytotoxic properties of methanolic extract from Baccharis obtusifolia [PDF]
International Journal of Medicinal Chemistry, 2018, 2019 Some species of the Baccharis genus have been shown to possess important biomedical properties, including cytotoxic activity. In this study, we examined the cytotoxic effect of methanol extract from Baccharis obtusifolia (Asteraceae) in cancer cell lines of prostate (PC-3), colon (RKO), astrocytoma (D-384), and breast (MCF-7).
arxiv +1 more source
Serial stereotactic biopsy of brainstem lesions in adults improves diagnostic accuracy compared with MRI only. [PDF]
, 2009 Objective: The aim of the current prospective study was to analyse the validity of MRI based diagnosis of brainstem gliomas which was verified by stereotactic biopsy and follow-up evaluation as well as to assess prognostic factors and risk profile ...
Grau, S. +5 more
core +3 more sources
Indian Journal of Pathology and Microbiology, 2010 Pilomyxoid astrocytoma (PMA) is a recently described brain tumor. PMA shares similar features with pilocytic astrocytoma (PA), the most common central nervous system (CNS) tumor in the pediatric population, yet displays subtle histologic differences.
Azad Sheenam +6 more
openaire +3 more sources
Scientific Reports, 2023 Astrocytoma is a common brain tumor that can occur in any part of the central nervous system. This tumor is extremely harmful to patients, and there are no clear studies on the risk factors for astrocytoma of the brain.
Ruiqi Wang +6 more
doaj +1 more source
The Diagnostic Significance of CXCL13 in M2 Tumor Immune Microenvironment of Human Astrocytoma
Pathology and Oncology Research, 2022 Background: CXCL13 may act as a mediator of tumor-associated macrophage immunity during malignant progression.Objective: The present study clarifies the clinicopathological significances of CXCL13 and its corresponding trend with M2 macrophage in human ...
Shu-Jyuan Chang +7 more
doaj +1 more source
Elevated expression of HSP10 protein inhibits apoptosis and associates with poor prognosis of astrocytoma. [PDF]
PLoS ONE, 2017 Astrocytoma is the most common type of primary malignant brain tumor, with pretty lowly 5-year survival rate in patients. Although extended surgical removal of the tumor and postoperative chemotherapy/radiotherapy executed, still there is large ...
Weibing Fan +5 more
doaj +1 more source
Al-Azhar Assiut Medical Journal, 2021 Background The primary brain tumors including astrocytic tumors, ranging from circumscribed into diffuse and glioblastoma (GBM), which is considered as a highly malignant neoplasm of the central nervous system.
Mohamed Y Ali, Marwa A El Kholy
doaj +1 more source