Results 41 to 50 of about 109,064 (360)
Clinical Cancer Research, 2018 Purpose: Pilocytic astrocytoma is the most common childhood brain tumor, characterized by constitutive MAPK activation. MAPK signaling induces oncogene-induced senescence (OIS), which may cause unpredictable growth behavior of pilocytic astrocytomas. The
J. Buhl +49 more
semanticscholar +1 more source
Mathematical model of brain tumour growth with drug resistance [PDF]
, 2020 Brain tumours are masses of abnormal cells that can grow in an uncontrolled way in the brain. There are different types of malignant brain tumours. Gliomas are malignant brain tumours that grow from glial cells and are identified as astrocytoma, oligodendroglioma, and ependymoma.
arxiv +1 more source
Genetic alterations in gliosarcoma and giant cell glioblastoma [PDF]
, 2015 The majority of glioblastomas develop rapidly with a short clinical history (primary glioblastoma IDH wild-type), whereas secondary glioblastomas progress from diffuse astrocytoma or anaplastic astrocytoma.
ANTONELLI, MANILA +13 more
core +1 more source
Scientific Reports, 2021 Astrocytoma is the most common glial tumour of the CNS. The most malignant form is grade IV Astrocytoma, also called Glioblastoma. Due to its heterogeneity, aggressiveness and lethal nature scientists are trying to find less invasive methods for early ...
Rūta Urbanavičiūtė +4 more
doaj +1 more source
Pilocytic astrocytoma: pathology, molecular mechanisms and markers
Acta Neuropathologica, 2015 Pilocytic astrocytomas (PAs) were recognized as a discrete clinical entity over 70 years ago. They are relatively benign (WHO grade I) and have, as a group, a 10-year survival of over 90 %.
V. Collins +2 more
semanticscholar +1 more source
Immunocompetent murine models for the study of glioblastoma immunotherapy. [PDF]
, 2014 Glioblastoma remains a lethal diagnosis with a 5-year survival rate of less than 10%. (NEJM 352:987-96, 2005) Although immunotherapy-based approaches are capable of inducing detectable immune responses against tumor-specific antigens, improvements in ...
Bloch, Orin +9 more
core +2 more sources
Positron emission tomography of sodium glucose cotransport activity in high grade astrocytomas. [PDF]
, 2018 A novel glucose transporter, the sodium glucose cotransporter 2 (SGLT2), has been demonstrated to contribute to the demand for glucose by pancreatic and prostate tumors, and its functional activity has been imaged using a SGLT specific PET imaging probe,
Barrio, Jorge R +7 more
core +2 more sources
Cancer Science, 2016 The PIM1 protein is an important regulator of cell proliferation, the cell cycle, apoptosis, and metabolism in various human cancers. MicroRNAs (miRNAs) are powerful post‐transcriptional gene regulators that function through translational repression or ...
Danni Deng +9 more
semanticscholar +1 more source
Graph complexity analysis identifies an ETV5 tumor-specific network in human and murine low-grade glioma [PDF]
, 2018 Conventional differential expression analyses have been successfully employed to identify genes whose levels change across experimental conditions.
Bush, Erin C +7 more
core +5 more sources
Expression of Ki 67 and P53 immunohistochemical markers in central nervous system astrocytoma
مجلة كلية الطب, 2015 Background: Astrocytic tumors are the most common primary tumors of the central nervous system. Several grading systems are used to grade astrocytomas.
Mahmood Sh. Mahmood +1 more
doaj +1 more source