Results 1 to 10 of about 843,093 (261)
Screening for generality in asymmetric catalysis. [PDF]
Nature, 2022 Research in the field of asymmetric catalysis over the past half century has resulted in landmark advances, enabling the efficient synthesis of chiral building blocks, pharmaceuticals, and natural products. A small number of asymmetric catalytic reactions have been identified that display high selectivity across a broad scope of substrates; not ...
Wagen CC +3 more
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Holistic prediction of enantioselectivity in asymmetric catalysis. [PDF]
Nature, 2019 When faced with unfamiliar reaction space, synthetic chemists typically apply the reported conditions (reagents, catalyst, solvent and additives) of a successful reaction to a desired, closely related reaction using a new substrate type. Unfortunately, this approach often fails owing to subtle differences in reaction requirements.
Reid JP, Sigman MS.
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Asymmetric catalysis mediated by a mirror symmetry-broken helical nanoribbon [PDF]
Nature Communications, 2019 If asymmetric catalysts were available by mirror symmetry breaking, an important insight may be given to how the biomolecular homochirality emerged in nature. Here, the authors report the first example of asymmetric catalysis by employing mirror symmetry-
Zhaocun Shen +8 more
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Further Developments and Applications of Oxazoline-Containing Ligands in Asymmetric Catalysis. [PDF]
Chem Rev, 2021 The chiral oxazoline motif is present in many ligands that have been extensively applied in a series of important metal-catalyzed enantioselective reactions.
Connon R, Roche B, Rokade BV, Guiry PJ.
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Aggregation-Induced Catalysis: Asymmetric Catalysis with Chiral Aggregates [PDF]
Research, 2023 So far, there have been 4 methods to control chirality including the use of chiral auxiliaries, reagents, solvents, and catalysts documented in literature and textbooks.
Yao Tang +9 more
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Nature Communications, 2023 Asymmetric electrochemical synthesis via ion-pairing catalysis is challenging due to interference of the electrolyte with the ion-pairing catalyst.
Xuefeng Tan, Qingli Wang, Jianwei Sun
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Ferrocene-derived P,N ligands: synthesis and application in enantioselective catalysis [PDF]
Green Processing and Synthesis, 2013 Due to their unique steric and electronic properties, air-stability and modular structure, chiral hybrid P,N-ferrocenyl ligands play a prominent role in the field of asymmetric catalysis.
Noël Timothy, Van der Eycken Johan
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Asymmetric Ion‐Pairing Catalysis [PDF]
Angewandte Chemie International Edition, 2012 AbstractCharged intermediates and reagents are ubiquitous in organic transformations. The interaction of these ionic species with chiral neutral, anionic, or cationic small molecules has emerged as a powerful strategy for catalytic, enantioselective synthesis.
Brak, Katrien, Jacobsen, Eric
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Heterobifunctional Rotaxanes for Asymmetric Catalysis. [PDF]
Angew Chem Int Ed Engl, 2020 AbstractHeterobifunctional rotaxanes serve as efficient catalysts for the addition of malonates to Michael acceptors. We report a series of four different heterobifunctional rotaxanes, featuring an amine‐based thread and a chiral 1,1′‐binaphthyl‐phosphoric‐acid‐based macrocycle.
Pairault N +6 more
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Asymmetric Catalysis Mediated by Synthetic Peptides, Version 2.0: Expansion of Scope and Mechanisms. [PDF]
Chem Rev, 2020 Low molecular weight synthetic peptides have been demonstrated to be effective catalysts for an increasingly wide array of asymmetric transformations. In many cases, these peptide-based catalysts have enabled novel multifunctional substrate activation ...
Metrano AJ +5 more
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