Results 41 to 50 of about 665,789 (291)

Progress in Stereoselective Haloamination of Olefins

Molecules
The regio- and stereoselective adjacent bifunctionalization of olefins with amine and halogen groups can be effectively accomplished through catalytic haloamination methods.
Guo Zhong, Jiayu Zhou, Bin Cui, Hui Sun
doaj   +1 more source

An Eight-Step Continuous-Flow Total Synthesis of Vitamin B1

Engineering
Vitamin B1 is widely applied in the healthcare and food industry as an antineuritic and antioxidant to maintain the normal functioning of nerve conduction, the heart, and the gastrointestinal tract.
Meifen Jiang, Minjie Liu, Weijian Li, Yingqi Xia, Fen-Er Chen   +4 more
doaj   +1 more source

Artificial Metalloenzymes in Asymmetric Catalysis: Key Developments and Future Directions

, 2015
Em enviat el pdf de l'article, pero disposem tant del preprint com el postprint.Artificial Metalloenzymes in Asymmetric Catalysis: Key Developments and Future ...
Jan-E. Bäckvall, PAMIES OLLÉ, OSCAR, Pàmies, Oscar, Bäckvall, Jan-E.,, Diéguez, Montserrat, DIÉGUEZ FERNÁNDEZ, MONTSERRAT   +5 more
core   +1 more source

Copper(I)-catalyzed asymmetric alkylation of α-imino-esters

Nature Communications, 2023
Asymmetric alkylation of enolates is one of the most direct and important reactions to prepare α-chiral carbonyl compounds. Except for the classical methods that rely on the use of chiral auxiliaries, asymmetric catalysis emerged as a powerful tool ...
Zong-Ci Liu, Zi-Qing Wang, Xuan Zhang, Liang Yin   +3 more
doaj   +1 more source

Asymmetric synthesis of tri- and tetrasubstituted trifluoromethyl dihydropyranones from alpha-aroyloxyaldehydes via NHC redox catalysis [PDF]

, 2014
We thank the Royal Society for a University Research Fellowship (A.D.S.), and the European Research Council under the European Union’s Seventh Framework Programme (FP7/2007-2013) ERC Grant Agreement No.
Smith, Andrew D., Philip M. Pickett, Philip M. Pickett (1771471), Alexandra M. Z. Slawin (809268), Alyn T. Davies (1771468), Andrew D. Smith, Davies, Alyn T., Pickett, Philip M., Alexandra M. Z. Slawin, Slawin, Alexandra M. Z., Alyn T. Davies, Andrew D. Smith (494170), Smith, Andrew D.; id_orcid, Slawin, Alexandra M. Z.; id_orcid   +13 more
core   +1 more source

Asymmetric catalysis: An enabling science [PDF]

Proceedings of the National Academy of Sciences, 2004
Chirality of organic molecules plays an enormous role in areas ranging from medicine to material science, yet the synthesis of such entities in one enantiomeric form is one of the most difficult challenges. The advances being made stem from the convergence of a broader understanding of theory and how structure begets function, the developments in the ...
openaire   +3 more sources

Observation of Hyperpositive Non-Linear Effects in Asymmetric Catalysis [PDF]

, 2019
Asymmetric amplification is a phenomenon that plays a key role in the emergence of homochirality in life. In asymmetric catalysis, theoretical and experimental models have been investigated for understanding how chiral amplification is possible, in ...
Yannick, Geiger, Stephane, Bellemin-Laponnaz, thierry, achard, aline, maisse-françois   +3 more
core   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source