Results 51 to 60 of about 36,768 (197)

Effect of angiotensin Ⅱ type 1 receptor on injury of renal tubular epithelial cells induced by high glucose

Linchuang shenzangbing zazhi, 2018
Objective To investigate the effect and possible mechanisms of angiotensin Ⅱ type1 receptor(AT1 R) on injury of renal tubular epithelial cells induced by high glucose.
ZHA Dong-qing, YAO Tao, GAO Ping, WU Xiao-yan   +3 more
doaj  

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

AT1 receptor signaling pathways in the cardiovascular system

, 2017
The importance of the renin angiotensin aldosterone system in cardiovascular physiology and pathophysiology has been well described whereas the detailed molecular mechanisms remain elusive.
O'Brien, Shannon, Shannon O’Brien, Rizzo, Victor, Eguchi, Satoru, Victor Rizzo, Kawai, Tatsuo, Forrester, Steven J., Satoru Eguchi, Baggett, Ariele, Tatsuo Kawai, Ariele Baggett, O'Brien, Shannon; id_orcid, Steven J. Forrester   +12 more
core   +1 more source

Novel fluorescent angiotensin AT1 receptor antagonists

, 2012
© 2012 Dr. Marilena A. GiarrussoHypertension is a severe condition that affects many people worldwide. The pathophysiology of hypertension is unknown. Sartans (selective AT1 receptor antagonists) are known to be the most direct and widely used class of ...
Giarrusso, Marilena A.
core   +1 more source

Species Dynamics and Gene Expression in Algal Polycultures Under Mixotrophic Cultivation in Outdoor Pilot‐Scale Nordic Conditions

Biotechnology and Bioengineering, EarlyView.
These results demonstrate that mixotrophic conditions drive both microbial community shifts and metabolic reprogramming, underscoring the importance of cultivation strategy and polyculture selection for targeted applications such as nutrient recovery and bioproduct generation.
Quyen Nham, Hanna Farnelid, Catherine Legrand, Elin Lindehoff   +3 more
wiley   +1 more source

Erythropoiesis and Blood Pressure Are Regulated via AT1 Receptor by Distinctive Pathways. [PDF]

PLoS ONE, 2015
The renin-angiotensin system (RAS) plays a central role in blood pressure regulation. Although clinical and experimental studies have suggested that inhibition of RAS is associated with progression of anemia, little evidence is available to support this ...
Hideki Kato, Junji Ishida, Taiji Matsusaka, Tomohiro Ishimaru, Keiji Tanimoto, Fumihiro Sugiyama, Ken-Ichi Yagami, Masaomi Nangaku, Akiyoshi Fukamizu   +8 more
doaj   +1 more source

AT1 receptor agonistic antibodies, hypertension, and preeclampsia

, 2004
Immunologic mechanisms and putatively circulating mediators of preeclampsia are not a new idea, but are nevertheless compelling. Here we review studies relating to the role of agonistic antibodies that bind the second extracellular loop of the ...
Homuth, V., Ralf Dechend, Luft, F.C., Mueller, D.N., Krause, M., Wallukat, G., Volker Homuth, Manya Krause, Dechend, R., Dudenhausen, J., Joachim Dudenhausen, Gerd Wallukat, Dominik N. Müller, Friedrich C. Luft   +13 more
core   +1 more source

MICU1-dependent mitochondrial calcium uptake regulates lung alveolar type 2 cell plasticity and lung regeneration

JCI Insight, 2022
Lung alveolar type 2 (AT2) cells are progenitors for alveolar type 1 (AT1) cells. Although many factors regulate AT2 cell plasticity, the role of mitochondrial calcium (mCa2+) uptake in controlling AT2 cells remains unclear. We previously identified that
Mir Ali, Xiaoying Zhang, Ryan LaCanna, Dhanendra Tomar, John W. Elrod, Ying Tian   +5 more
doaj   +1 more source

Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair

Cell Reports, 2020
Summary: Lung alveolar epithelium is composed of alveolar type I (AT1) and type II (AT2) cells. AT1 cells mediate gas exchange, whereas AT2 cells act as progenitor cells to repair injured alveoli.
Qian Chen, Jalees Rehman, Manwai Chan, Panfeng Fu, Steven M. Dudek, Viswanathan Natarajan, Asrar B. Malik, Yuru Liu   +7 more
doaj   +1 more source

Faith, Sustainability and Consumer Trust in Halal–Green Cosmetics: A Dual‐Trust Model Among Muslim Women

Business Strategy and the Environment, EarlyView.
ABSTRACT This study examines how firms secure legitimacy in markets where faith‐based expectations and environmental responsibility intersect, focusing on halal–green cosmetics among Muslim women. It conceptualises halal trust and green trust as parallel legitimacy pathways reflecting faith‐based legitimacy and environmental credibility, respectively ...
Dwi Suhartanto, Ani Kartikasari, Gundur Leo, Sitti Nur Azmi Fadhlurrahmah, Adelia Athifah Ambartola   +4 more
wiley   +1 more source