Results 71 to 80 of about 13,112 (166)

Investıgatıon Of The Relatıonshıp Between At1r And Cytokın Gene Polymorphısm In Renal Transplantatıon

, 2018
Böbrek nakli son dönem böbrek yetmezliğinin tedavisinde altın standart olarak önemini korumaktadır. Transplantasyon immünolojisi araştırmaları ile geliştirilen tanı ve tedavide yeni yaklaşımlar, günümüzde başarı oranlarını artırmıştır.
Yantır, Emel
core  

Effect of removing the CT of tubulin on its interaction with the AT1R CT.

, 2013
(A) GST and GST fusion proteins encoding the AT1R CT were incubated with 1 µg of purified tubulin or tubulin S in which the negatively charged CT was cleaved. The bound tubulin and tubulin S were determined by Western blotting usingα-tubulin antibodies. (
Xiaoping Zhang (124848), Guangyu Wu (295586), Hong Wang (13528), Matthew T. Duvernay (382190), Shu Zhu (356373)   +4 more
core   +1 more source

Nucleolin in the cell membrane promotes Ang II-mediated VSMC phenotypic switching by regulating the AT1R internalization function

Background Nucleolin (NCL) plays an important regulatory role in angiotensin II (Ang II)-induced phenotypic switching of vascular smooth muscle cells (VSMCs). The aim of this study was to discuss its potential regulatory mechanisms.
Yinzhuang Zhang, Zhuoni Mao, Chenyu Lou, Dan Huang, Li Fang, Zhijie Shen   +5 more
core   +1 more source

RBC cAMP-PKA-dependent pathway and AT1R vs β-AR dimer/complex.

, 2019
RBC cAMP-PKA-dependent pathway and AT1R vs β-AR dimer/complex.
Jing Zhang (23775), George Lykotrafitis (3797242), Biree Andemariam (2513386), Sasia-Marie Jones (6588728)   +3 more
core   +1 more source

Targeting Kinin B1R Attenuates Hypertension Through AT1R-Dependent Mechanisms

BACKGROUND: Neurogenic hypertension is chronically high blood pressure that is initiated and maintained through excessive sympathetic nervous system activity and has been associated with increased B1R (kinin B1 receptor) activation.
Lazartigues, Eric, Sriramula, Srinivas, Theobald, Drew, Bessetti, Riley N, Feng Earley, Yumei, Litwa, Karen   +5 more
core   +1 more source

Effects of mutating the tubulin-binding site on AT1R-mediated activation of ERK1/2.

, 2013
(A) and (B) HEK293 cells were transfected with wild-type AT1R or its mutant 4K–4E tagged with GFP at their C-termini (A) or with HA at their N-termini (B). The cells were then stimulated with Ang II at a concentration of 1 µM for 2 min. ERK1/2 activation
Xiaoping Zhang (124848), Guangyu Wu (295586), Hong Wang (13528), Matthew T. Duvernay (382190), Shu Zhu (356373)   +4 more
core   +1 more source

Distinct Dynamics of Biased Agonists Bound AT1R [PDF]

Biophysical Journal, 2018
Sangbae Lee, Anita K. Nivedha, HyunDeok Song, Nagarajan Vaidehi   +3 more
openaire   +1 more source

OXIDATIVE STRESS AND RENAL AT1R FUNCTION DURING HYPERTENSION

, 2012
Angiotensin (Ang) II via renal Ang II type 1 receptors (AT1R) modulates proximal tubular Na/K-ATPase such that, low concentrations of Ang II stimulates Na/K-ATPase whereas at high concentrations the stimulatory effect is lost. Studies show that oxidative
Javkhedkar, Apurva
core  

Angiotensin II type 1 and type 2 receptors modulate TWIK1 channel expression and pain sensitivity in a rat model of neuropathic pain. [PDF]

Front Pharmacol
Peralta ED, Stable García Y, Soria SV, Benitez SG, Acosta CG.   +4 more
europepmc   +1 more source

AT1R in Central Nervous System Disorders: Unveiling Novel Mechanisms and Therapeutic Avenues for Addiction. [PDF]

Addict Biol
Lv J, Zhu D, Song S, Zhou J, Zhang X, Zhou W, Liu Y, Si Z.   +7 more
europepmc   +1 more source