Results 161 to 170 of about 186,580 (246)
Metabolism‐based atrazine‐resistant Amaranthus tuberculatus populations ACR and MCR exhibit little or no cross‐resistance to amicarbazone and metribuzin, suggesting that non‐halogenated Group 5 herbicides can be utilized to re‐establish effective control.
Alexander J Lopez +5 more
wiley +1 more source
Exploring the Impact of RNU4‐2 Defects on Neurodevelopmental Disorders in a Korean Population
Among 15 450 Korean individuals, noncoding RNU4‐2 variants, primarily the recurrent de novo n.64_65insT, make up 0.72% of neurodevelopmental disorders. Modeling and RNA‐seq suggest U4/U6 disruption and abnormal 5′ splice‐site selection, supporting routine use of WGS analysis for reanalyzing unresolved cases. ABSTRACT Neurodevelopmental disorders (NDDs)
Juhyeon Hong +20 more
wiley +1 more source
An Outflow Tract Myocardium‐Specific Enhancer at the Sema3c Locus During Heart Development
Focusing on an OFT‐specific differentially accessible region, in the present study, we defined a distal OFT myocardial enhancer whose activity depends on GATA binding sites. This enhancer provides insight into the mechanisms underlying spatially restricted Sema3c expression involved in OFT development.
Yunce Wang +5 more
wiley +1 more source
Ataxin‐1 has been recently implicated in B cell regulation in the context of multiple sclerosis pathology. In this study, we used a multiomics pipeline to profile the B cell transcriptome, epigenome, and proteome in response to encephalitogenic challenges.
Jonathan J. Carver +6 more
wiley +1 more source
Beyond chromatin accessibility: bulk ATAC-seq as an integrative assay to portray genomes and epigenomes. [PDF]
Toumi I +4 more
europepmc +1 more source
Single‐Cell CRISPR: An Efficient Strategy for Decoding Plant Cis‐Regulatory Complexity
ABSTRACT The generation of complex traits involves the coordinated interplay of multiple gene networks. Elucidating the function of transcriptional cis‐regulatory elements (CREs) in regulating gene expression is crucial for understanding complex regulatory pathways and improving our ability to modify macro‐phenotypes.
Yuanhang Zhang +5 more
wiley +1 more source
ATAC-seq of low-input and cryopreserved primordial germ cells reveals functional enhancers. [PDF]
Kawaguchi A +8 more
europepmc +1 more source
Integrated physical and virtual modeling provides a scalable framework to overcome sample scarcity, recapitulate mucosal melanoma biology, and accelerate translational discovery toward precision medicine. ABSTRACT Mucosal melanoma (MM) is a rare and lethal subtype of melanoma, disproportionately affecting Asian populations and exhibiting distinct ...
Xiangjie Jin +4 more
wiley +1 more source
RAGER: A user-friendly computational platform for integrated analysis of RNA-Seq and ATAC-seq data. [PDF]
Liu Y, Liu Y, Zhang Z, Li F, Yu H, Lu L.
europepmc +1 more source
Advancing clinical precision medicine via peripheral blood immune single‐cell omics
Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Liyang Li +5 more
wiley +1 more source

