Results 101 to 110 of about 20,819 (199)
The FASEB Journal, Volume 40, Issue 15, 15 August 2026.This study explored the crosstalk between ferroptosis‐related genes and peripheral immune alterations in Parkinson's disease. We constructed a gene signature and classified molecular subtypes, and further pinpointed key ferroptosis‐associated molecules in immune cells and neuronal cells.
Lei Cheng +5 more
wiley +1 more source
LiCl causes an acute decrease in ataxia telangiectasia mutated (ATM) protein levels in L6 myotubes
The FASEB Journal, 2010 We have previously found that insulin‐like growth factor 1 (IGF‐1) causes an acute increase in levels of ATM in cultured myotubes and in mouse skeletal muscle and that serum starvation (SS) of myotubes causes concomitant increases in levels of the AMP‐activated protein kinase (AMPK) and ...
Rona Robinson‐Hill +2 more
openaire +1 more source
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
Pediatric Blood &Cancer, Volume 73, Issue 8, August 2026.ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2019 Adenoid cystic carcinoma (ACC) is one of the high grade malignant tumors in salivary glands, prognosticallycharacterized by multiple recurrences and late distant metastasis. Recently, Myb-NFIB fusion or rearrangements of Myb have been detected as a hallmark of ACC. However, no biological marker estimating the outcome of ACC has been proven yet. Purpose
Mrs. Shadavlonjid Bazarsad +1 more
openaire +1 more source
Advanced Science, Volume 13, Issue 44, 7 August 2026.Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth +10 more
wiley +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković +6 more
wiley +1 more source
Staging concept for aging management: Definition, mechanism, and coping strategies
VIEW, Volume 7, Issue 4, August 2026.We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
Chromium (VI) Activates Ataxia Telangiectasia Mutated (ATM) Protein [PDF]
Journal of Biological Chemistry, 2003 Linan Ha +2 more
openaire +1 more source
Chinese Medical Journal. Background:. Long non-coding RNAs (lncRNAs) plays an important role in the progression of gastric cancer (GC). Their involvement ranges from genetic regulation to cancer progression.
Wenwei Liu +9 more
doaj +1 more source
Cancer Management and Research, 2022 Xiwen Wang, Jungang Zhao Department of Thoracic Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, 110004, People’s Republic of ChinaCorrespondence: Jungang ZhaoDepartment of Thoracic Surgery, Shengjing Hospital of China Medical
Wang X, Zhao J
doaj