Results 151 to 160 of about 1,665,599 (197)
The WHO Classification of Genetic Tumour Syndromes: Considerations for Genetics
Clinical Genetics, Volume 110, Issue 3, Page 389-401, September 2026.The WHO Classification of Tumours underpins the diagnosis of neoplastic conditions. The new WHO classification of genetic tumour syndromes (GTS) provides international standards for their diagnosis. This diagram highlights the chromosomal distribution of the genes involved in the GTS covered in this classification.
Ian A. Cree +18 more
wiley +1 more source
, 2007 Supplementary Table S5 from Ataxia Telangiectasia-Mutated–Dependent DNA Damage Checkpoint Functions Regulate Gene Expression in Human ...
Richard S. Paules (7988831) +7 more
core +1 more source
When to consider an inborn error of immunity: clues for physicians
Internal Medicine Journal, Volume 56, Issue 9, Page 1488-1499, September 2026.Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley +1 more source
Skin Aging: From Molecular Mechanisms to Therapeutic and Technological Innovations
Journal of Cellular and Molecular Medicine, Volume 30, Issue 18, September 2026.ABSTRACT Aging is a complex, pervasive biological process that causes irreversible declines in function across organ systems. The skin, the body's largest organ, interfaces directly with the external environment and undergoes aging driven by intrinsic (chronological) and extrinsic (environmental) factors, which result in functional deterioration and ...
Sanyin Chen +4 more
wiley +1 more source
, 2007 Supplementary Table S1 from Ataxia Telangiectasia-Mutated–Dependent DNA Damage Checkpoint Functions Regulate Gene Expression in Human ...
Richard S. Paules (7988831) +7 more
core +1 more source
RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation
Photochemistry and Photobiology, Volume 102, Issue 5, Page 1138-1149, September/October 2026.UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan +3 more
wiley +1 more source
, 2007 Supplementary Table S6 from Ataxia Telangiectasia-Mutated–Dependent DNA Damage Checkpoint Functions Regulate Gene Expression in Human ...
Richard S. Paules (7988831) +7 more
core +1 more source
, 2007 Supplementary Table S2 from Ataxia Telangiectasia-Mutated–Dependent DNA Damage Checkpoint Functions Regulate Gene Expression in Human ...
Richard S. Paules (7988831) +7 more
core +1 more source
, 2007 Supplementary Table S4 from Ataxia Telangiectasia-Mutated–Dependent DNA Damage Checkpoint Functions Regulate Gene Expression in Human ...
Richard S. Paules (7988831) +7 more
core +1 more source
Current and potential therapeutic strategies for the treatment of ataxia-telangiectasia
, 2007 Ataxia-telangiectasia (A-T) is a rare autosomal recessive genetic disorder characterized by progressive neurodegeneration, a high risk of cancer and immunodeficiency. These patients are also hypersensitive to radiotherapy.
Bottle, S (15815519) +3 more
core