Results 161 to 170 of about 1,665,599 (197)

The investigated case of etiology of chylous pleural effusion: Ataxia-telangiectasia

open access: yes
Ataxia-telangiectasia is an autosomal recessive, rare, neurodegenerative multisystem disorder characterized by ataxia-telangiectasia, cerebellar ataxia, oculocutaneous telangiectasia, immunodeficiency, progressive respiratory failure associated with ...
Sak, I   +4 more
core  

891 TP53 binding protein-1 and mutated in Ataxia-Telangiectasia gene variants affect TP53 mutations in lung cancer

open access: yesEuropean Journal of Cancer Supplements, 2010
S. Zienolddiny, V. Skaug, A. Haugen
openaire   +1 more source

Radioresistant malignant myoepithelioma of the breast with high level of ataxia telangiectasia mutated protein

Journal of Medical Imaging and Radiation Oncology, 2009
SummaryMalignant myoepithelioma of the breast (MMB) is a rare and often aggressive disease with poor prognosis. Little is known regarding its optimal treatment and progression. We describe the clinical history of a woman following excision of a benign adenomyoepithelioma which recurred years later as a radioresistant malignant myoepithelioma with high ...
Martin Lavin, P H Graham
exaly   +6 more sources

Ataxia-Telangiectasia Mutated Modulation of Carbon Metabolism in Cancer

open access: yesFrontiers in Oncology, 2017
The ataxia-telangiectasia mutated (ATM) protein kinase has been extensively studied for its role in the DNA damage response and its association with the disease ataxia telangiectasia.
Erika Dahl, Katherine Aird
exaly   +2 more sources

Targeting the Ataxia Telangiectasia Mutated Protein in Cancer Therapy

Current Drug Targets, 2016
Genotoxic anticancer drugs explicate their effects damaging DNA, thus triggering a coordinated signal-transduction network called DNA Damage Response (DDR). Ataxia Telangiectasia Mutated (ATM) protein plays a central role in this response: activated by DNA damage, ATM phosphorylates itself and downstream effectors that arrest cell cycle allowing for ...
Donatella, Vecchio, Guido, Frosina
openaire   +2 more sources

Ataxia-Telangiectasia and RAD3-Related and Ataxia-Telangiectasia-Mutated Proteins in Epithelial Ovarian Carcinoma: Their Expression and Clinical Significance.

Anticancer research, 2015
The expression patterns of the key DNA damage response-related proteins, ataxia-telangiectasia and tfiih/ner complex atp-dependent 5'-3' dna helicase subunit rad3 (RAD3)-related (ATR) and ataxia-telangiectasia-mutated (ATM) proteins in ovarian cancer are not well-known.
Banghyun, Lee   +7 more
openaire   +2 more sources

Review: ATM: the protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia

International Journal of Radiation Biology, 1999
To provide an update on the product of the ATM gene mutated in the human genetic disorder ataxia-telangiectasia (A-T).The product of the ATM gene mutated in the human genetic disorder A-T is a 350 kDa protein that plays a central role in the regulation of a number of cellular processes.
Lavin, Martin F., Khanna, Kum Kum
openaire   +6 more sources

Nanotube-Based Colorimetric Probe for Ultrasensitive Detection of Ataxia Telangiectasia Mutated Protein

Analytical Chemistry, 2011
We have developed a nanotube-based colorimetric probe using multiwalled carbon nanotubes (MWNTs), anti-immunoglobulin G (anti-IgG), and horseradish peroxidase (HRP). The probe was used as an alternative to conventional colorimetric conjugates to obtain amplified signals in a sandwich-type immunoassay for ataxia telangiectasia mutated (ATM), a potential
Qingzhi, Zhang   +5 more
openaire   +2 more sources

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