Results 161 to 170 of about 41,016 (281)

Targeted Cancer Therapy Based on Acetylation and Deacetylation of Key Proteins Involved in Double-Strand Break Repair

Cancer Management and Research, 2022
Xiwen Wang, Jungang Zhao Department of Thoracic Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, 110004, People’s Republic of ChinaCorrespondence: Jungang ZhaoDepartment of Thoracic Surgery, Shengjing Hospital of China Medical
Wang X, Zhao J
doaj  

Ataxia with oculomotor apraxia type 2: a clinical, pathologic, and genetic study [PDF]

, 2006
BACKGROUND: Ataxia with oculomotor apraxia type 2 (AOA2) is characterized by onset between age 10 and 22 years, cerebellar atrophy, peripheral neuropathy, oculomotor apraxia (OMA), and elevated serum alpha-fetoprotein (AFP) levels. Recessive mutations in
BANFI S, BARBIERI, FABRIZIO, CASALI C., CHESSA L, CRISCUOLO C, DE MICHELE, GIUSEPPE, DI GIANDOMENICO S, FILLA, ALESSANDRO, GALLOSTI L, GRIECO GS, MANCINI P, PIANE M, PIERELLI F, RIZZUTO N, SACCA', FRANCESCO, SANTORELLI FM   +15 more
core  

Formaldehyde initiates memory and motor impairments under weightlessness condition

npj Microgravity
During space flight, prolonged weightlessness stress exerts a range of detrimental impacts on the physiology and psychology of astronauts. These manifestations encompass depressive symptoms, anxiety, and impairments in both short-term memory and motor ...
Tianhao Mei, Ying Chen, Yajuan Gao, Hang Zhao, Xingzhou Lyu, Jing Lin, Tianye Niu, Hongbin Han, Zhiqian Tong   +8 more
doaj   +1 more source

DNA-dependent Protein Kinase Regulates DNA End Resection in Concert with Mre11-Rad50-Nbs1 (MRN) and Ataxia Telangiectasia-mutated (ATM)*

Journal of Biological Chemistry, 2013
Yi Zhou, T. Paull
semanticscholar   +1 more source

Loss of atm sensitises p53-deficient cells to topoisomerase poisons and antimetabolites [PDF]

, 2017
Background: Ataxia-telangiectasia is a pleiotropic autosomal recessive disorder caused by mutations in the ATM gene. In addition to a profound cancer predisposition, another hallmark of ataxia-telangiectasia is radiosensitivity.
Fedier, A., Fink, D., Haller, U., Howell, S. B., Schlamminger, M., Schwarz, V. A.   +5 more
core  

Ataxia–telangiectasia mutated kinase‐mediated upregulation of NKG2D ligands on leukemia cells by resveratrol results in enhanced natural killer cell susceptibility

Cancer Science, 2013
E. J. Luis, Takami Akiyoshi, Trung Ly, Nakao Shinji   +3 more
semanticscholar   +1 more source

Role of N-terminal domains of p400 ATPase in the ATM interaction and DNA damage response : a thesis presented in partial fulfillment of the requirements for a the degree of Master of Science (MSc) in Genetics at Massey University, Manawatū, New Zealand [PDF]

, 2016
Efficient repair of damaged DNA and preservation of genomic integrity is integral in the maintenance of proper cellular function and prevention of unrestricted cell proliferation. One critical threat to the stability of the genome is the double strand
Weber, Lauren Elizabeth
core  

MicroRNA-18a upregulates autophagy and ataxia telangiectasia mutated gene expression in HCT116 colon cancer cells.

Molecular Medicine Reports, 2013
A. B. Qased, He-qing Yi, Nan Liang, Shumei Ma, Shixing Qiao, Xiaodong Liu   +5 more
semanticscholar   +1 more source

The Kinase Activity of Ataxia-Telangiectasia Mutated Interferes with Adenovirus E4 Mutant DNA Replication

Journal of Virology, 2013
D. Gautam, E. Bridge
semanticscholar   +1 more source

Ataxia telangiectasia mutated (ATM); DNA-dependent protein kinase (DNA-PK) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source