Results 141 to 150 of about 9,929 (238)

Antisense oligonucleotide-mediated exon skipping as a strategy to reduce proteolytic cleavage of ataxin-3 [PDF]

, 2016
Lodewijk J.A. Toonen, Iris Schmidt, Martijn S. Luijsterburg, Haico van Attikum, Willeke van Roon‐Mom   +4 more
openalex   +1 more source

Enzymatic production of mono‐ubiquitinated proteins for structural studies: The example of the Josephin domain of ataxin‐3 [PDF]

, 2013
Serena Faggiano, Rajesh P. Menon, Geoff Kelly, John E. McCormick, Sokol V. Todi, K. Matthew Scaglione, Henry L. Paulson, Annalisa Pastore   +7 more
openalex   +1 more source

Label-free autofluorescence lifetime reveals the structural dynamics of ataxin-3 inside droplets formed via liquid-liquid phase separation. [PDF]

Sci Rep, 2023
Matsuura U, Tahara S, Kajimoto S, Nakabayashi T.   +3 more
europepmc   +1 more source

KPNB1 modulates the Machado-Joseph disease protein ataxin-3 through activation of the mitochondrial protease CLPP. [PDF]

Cell Mol Life Sci, 2022
Abeditashi M, Weber JJ, Pereira Sena P, Velic A, Kalimeri M, Incebacak Eltemur RD, Schmidt J, Hübener-Schmid J, Hauser S, Macek B, Riess O, Schmidt T.   +11 more
europepmc   +1 more source

Pathophysiological interplay between O-GlcNAc transferase and the Machado-Joseph disease protein ataxin-3. [PDF]

Proc Natl Acad Sci U S A, 2021
Pereira Sena P, Weber JJ, Watchon M, Robinson KJ, Wassouf Z, Hauser S, Helm J, Abeditashi M, Schmidt J, Hübener-Schmid J, Schöls L, Laird AS, Riess O, Schmidt T.   +13 more
europepmc   +1 more source

Preventing Ataxin-3 protein cleavage mitigates degeneration in a Drosophila model of SCA3 [PDF]

, 2009
Joonil Jung, Kexiang Xu, Derek Lessing, Nancy M. Bonini   +3 more
openalex   +1 more source

Erinacine A-Enriched Hericium erinaceus Mycelium Ethanol Extract Lessens Cellular Damage in Cell and Drosophila Models of Spinocerebellar Ataxia Type 3 by Improvement of Nrf2 Activation

Antioxidants
Spinocerebellar ataxia type 3 (SCA3), caused by the abnormal expansion of polyglutamine (polyQ) in the ataxin-3 protein, is one of the inherited polyQ neurodegenerative diseases that share similar genetic and molecular features.
Yu-Ling Wu, Hai-Lun Sun, Jui-Chih Chang, Wei-Yong Lin, Pei-Yin Chen, Chin-Chu Chen, Li-Ya Lee, Chien-Chun Li, Mingli Hsieh, Haw-Wen Chen, Ya-Chen Yang, Chin-San Liu, Kai-Li Liu   +12 more
doaj   +1 more source

Adulte Neurogenese in der Orexin/Ataxin-3 Maus

, 2016
Christiane Wolf
openalex   +1 more source

Disulfiram facilitates ataxin-3 nuclear translocation and potentiates the cytotoxicity in a cell model of SCA3

, 2019
Zijian Wang
openalex   +2 more sources

Polyglutamine‐Expanded Ataxin‐3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood

, 2021
Jeannette Hübener‐Schmid, Kirsten Kuhlbrodt, Julien Peladan, Jennifer Faber, Magda M. Santana, Holger Hengel, Heike Jacobi, Kathrin Reetz, Héctor García‐Moreno, Mafalda Raposo, Judith van Gaalen, Jon Infante, Katharina M. Steiner, Jeroen de Vries, Marcel M. Verbeek, Paola Giunti, Luís Pereira de Almeida, Manuela Lima, Bart van de Warrenburg, Lüdger Schöls, Thomas Klockgether, Matthis Synofzik, European Spinocerebellar Ataxia Type‐3/Machado–Joseph Disease Initiative (ESMI) Study Group, Olaf Riess   +23 more
openalex   +1 more source