Results 141 to 150 of about 28,738 (248)

Data from ATF6-Mediated Signaling Contributes to PARP Inhibitor Resistance in Ovarian Cancer

, 2023
Alexandra McMellen, Tomomi M. Yamamoto, Lubna Qamar, Brooke E. Sanders, Lily L. Nguyen, Daniela Ortiz Chavez, Jaidev Bapat, Amber Berning, Zain Aryanpour, Joshua Johnson, Kian Behbakht, Elmar Nurmemmedov, Edward B. Chuong, Benjamin G. Bitler   +13 more
openalex   +1 more source

EFP1 is an ER stress-induced glycoprotein which interacts with the pro-apoptotic protein Par-4 [PDF]

, 2009
We have isolated the rat ortholog of EFP1 (EF-hand binding protein 1) as a novel interaction partner of the pro-apoptotic protein Par-4 (prostate apoptosis response-4).
Appel, Sarah, Boosen, Meike, Koplin, Ansgar, Maertens, Barbara, Preuss, Ute, Vetterkind, Susanne   +5 more
core   +1 more source

PTEN phosphatase inhibits metastasis by negatively regulating the Entpd5/IGF1R pathway through ATF6

, 2023
Yanlin Yu, Meng Dai, Liping Huang, Weiping Chen, Ellen Yu, Arnulfo Mendoza, Helen Michael, Chand Khanna, Marcus Bosenberg, Martin McMahon, Glenn Merlino   +10 more
openalex   +1 more source

The role of GRP78/ATF6/IRE1 and caspase-3/Bax/Bcl2 signaling pathways in the protective effects of gallic acid against cadmium-induced liver damage in rats. [PDF]

, 2023
Volkan Gelen, Emin Şengül, Serkan Yıldırım, İrfan Çınar   +3 more
openalex   +1 more source

E-cigarette aerosols induce unfolded protein response in normal human oral keratinocytes. [PDF]

, 2019
Objective: Since the introduction in 2004, global usage of e-cigarettes (ECs) has risen exponentially. However, the risks of ECs on oral health are uncertain.
Chen, Wei, Cui, Li, Elzakra, Naseim, Hu, Shen, Ji, Eoon Hye, Lee, Eon S, Messadi, Diana, Sun, Bingbing, Xia, Tian, Zhu, Yifang   +9 more
core  

QRICH1 regulates ATF6 transcription to affect pathological cardiac hypertrophy progression

Molecular Medicine
Abstract Background Many studies have shown that pathological cardiac hypertrophy is associated with active endoplasmic reticulum (ER) stress. Glutamine-rich protein 1 (QRICH1), as a transcriptional regulator, belongs to the caspase recruitment domain (CARD)-containing gene family.
Lihui Zhang, Hongping Chen, Guangmei Zou, Wenjuan Jia, Haibin Dong, Chunxiao Wang, Hua Wang, Yugang Liu, Da Teng, Bowen Xu, Lin Zhong, Lei Gong, Jun Yang   +12 more
openaire   +3 more sources

Endoplasmic reticulum stress, degeneration of pancreatic islet β-cells, and therapeutic modulation of the unfolded protein response in diabetes. [PDF]

, 2019
BackgroundMyriad challenges to the proper folding and structural maturation of secretory pathway client proteins in the endoplasmic reticulum (ER) - a condition referred to as "ER stress" - activate intracellular signaling pathways termed the unfolded ...
Colon-Negron, Kevin, Ghosh, Rajarshi, Papa, Feroz R   +2 more
core   +1 more source

Activation of the EIF2α/ATF4 and ATF6 Pathways in DU-145 Cells by Boric Acid at the Concentration Reported in Men at the US Mean Boron Intake [PDF]

, 2016
Sarah Kobylewski, Kimberly A. Henderson, Kristin Yamada, Curtis D. Eckhert   +3 more
openalex   +1 more source

Supplementary Figure 10 from Targeting the ATF6-Mediated ER Stress Response and Autophagy Blocks Integrin-Driven Prostate Cancer Progression

, 2023
Amanda J. Macke, Artem N. Pachikov, Taylor E. Divita, Mary E. Morris, Chad A. LaGrange, Melissa S. Holzapfel, Anatoly V. Kubyshkin, Evgeniya Y. Zyablitskaya, Tatiana P. Makalish, Sergey N. Eremenko, Haowen Qiu, Jean-Jack M. Riethoven, George P. Hemstreet, Armen Petrosyan   +13 more
openalex   +1 more source

Impact of ATF6 deletion on the embryonic brain development

Impact of ATF6 deletion on the embryonic brain development
PreKURA ...
Loc Dinh Nguyen, Ly Huong Nguyen, Dat Xuan Dao, Tsuyoshi Hattori, Mika Takarada-Iemata, Hiroshi Ishii, Takashi Tamatani, Hiroshi Kawasaki, Yohei Shinmyo, Kenta Onoue, Shigenobu Yonemura, Jun Zhang, Masato Miyake, Seiichi Oyadomari, Kazutoshi Mori, Osamu Hori   +15 more
openaire   +3 more sources