Analysis of the Effect of Atherosclerosis with the Changes of Hematocrit: A Computational Study on the Hemodynamics of Carotid Artery [PDF]
Atherosclerosis is a state wherein plaque (fat, cholesterol, and different substances) develops inside the veins that in the end prompts carotid artery stenosis which is a phase of narrowing in the huge courses situated on either side of the neck that convey blood to the brain, face, and head.
arxiv +1 more source
Exercise and Coronary Atherosclerosis: Observations, Explanations, Relevance, and Clinical Management. [PDF]
Physical activity and exercise training are effective strategies for reducing the risk of cardiovascular events, but multiple studies have reported an increased prevalence of coronary atherosclerosis, usually measured as coronary artery calcification ...
Aengevaeren, VL+7 more
core +3 more sources
Hemodynamic Bigger Hydrostatic Pressure Instead of Lower Shear Stress Aggravates Atherosclerosis [PDF]
The traditional view is that low shear stress of blood flow accelerates atherosclerosis. How does a low shear stress damage the vessel or aggravate atherosclerosis? It is a puzzling question. Furthermore, shear stress of veins is similar to that of Relatively Vulnerable Zones (RVZ) of arteries, while intimal thickening of veins is not obvious as the ...
arxiv +1 more source
MHC class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity [PDF]
Background—Plasmacytoid dendritic cells (pDCs) bridge innate and adaptive immune responses and are important regulators of immuno-inflammatory diseases. However, their role in atherosclerosis remains elusive.
Ait-Oufella, Hafid+16 more
core +2 more sources
Apolipoprotein E and Atherosclerosis: From Lipoprotein Metabolism to MicroRNA Control of Inflammation. [PDF]
Apolipoprotein (apo) E stands out among plasma apolipoproteins through its unprecedented ability to protect against atherosclerosis. Although best recognized for its ability to mediate plasma lipoprotein clearance in the liver and protect against ...
Hasty+6 more
core +2 more sources
Artery tertiary lymphoid organs control aorta immunity and protect against atherosclerosis via vascular smooth muscle cell lymphotoxin β receptors [PDF]
Tertiary lymphoid organs (TLOs) emerge during nonresolving peripheral inflammation, but their impact on disease progression remains unknown. We have found in aged Apoe−/− mice that artery TLOs (ATLOs) controlled highly territorialized aorta T cell ...
Beer, Michael+24 more
core +5 more sources
Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding [PDF]
Background: Atherosclerosis is an inflammatory process that develops in individuals with known risk factors that include hypertension and hyperlipidaemia, influenced by diet.
A Abbate+48 more
core +14 more sources
PRAS40 suppresses atherogenesis through inhibition of mTORC1-dependent pro-inflammatory signaling in endothelial cells [PDF]
Endothelial pro-inflammatory activation plays a pivotal role in atherosclerosis, and many pro-inflammatory and atherogenic signals converge upon mechanistic target of rapamycin (mTOR).
Althoff, Till F.+14 more
core +1 more source
Porphyromonas gingivalis lipopolysaccharide alters atherosclerotic-related gene expression in oxidized low-density-lipoprotein-induced macrophages and foam cells [PDF]
The molecular mechanism between atherosclerosis formation and periodontal pathogens is not clear although positive correlation between periodontal infections and cardiovascular diseases has been reported.
de Winther+23 more
core +2 more sources
2016 ESC/EAS GUIDELINES FOR THE MANAGEMENT OF DYSLIPIDAEMIAS
The Task Force for the Management of Dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS)Developed with the special contribution of the European Assocciation for Cardiovascular Prevention & ...
Alberico L. Catapano+18 more
doaj +1 more source