Results 1 to 10 of about 758,276 (338)

Lipoproteins and Atherosclerosis [PDF]

open access: greenJournal of Gerontology, 1951
Author(s): Gofman, John W.; Lindgren, Frank T.; Jones, Hardin B.; Lyon, Thomas P.; Strisower, Beverly.
John W. Gofman   +4 more
openalex   +5 more sources

Pathophysiology of Atherosclerosis

open access: yesInternational Journal of Molecular Sciences, 2022
Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and, followed by a cascade of events (accumulation of lipids, fibrous elements, and calcification), triggers the vessel narrowing and activation of inflammatory pathways. The
Shifa Jebari-Benslaiman   +7 more
openaire   +4 more sources

Atherosclerosis and Autoimmunity [PDF]

open access: yesMediators of Inflammation, 2018
Abstract Despite a decline in mortality rates in several countries, cardiovascular disease remains the leading cause of death responsible for approximately half of all deaths on the continent. Coronary artery disease and stroke are often the result of acute complications of atherosclerosis (AS) and atherothrombosis.
Francesca Romana Spinelli   +4 more
openaire   +3 more sources

Atherosclerosis [PDF]

open access: yesNature Reviews Disease Primers, 2019
Atherosclerosis, the formation of fibrofatty lesions in the artery wall, causes much morbidity and mortality worldwide, including most myocardial infarctions and many strokes, as well as disabling peripheral artery disease. Development of atherosclerotic lesions probably requires low-density lipoprotein, a particle that carries cholesterol through the ...
Peter, Libby   +7 more
openaire   +4 more sources

Partial duplication of the EGF precursor homology domain of the LDL-receptor protein causing familial hypercholesterolemia (FH-Salerno).

open access: yesJournal of Lipid Research, 1994
A novel mutation of low density lipoprotein (LDL)-receptor gene was found in an Italian family hypercholesterolemia (FH) patient during a screening of 300 FH patients.
S Bertolini   +9 more
doaj   +1 more source

MHC class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity [PDF]

open access: yes, 2014
Background—Plasmacytoid dendritic cells (pDCs) bridge innate and adaptive immune responses and are important regulators of immuno-inflammatory diseases. However, their role in atherosclerosis remains elusive.
Ait-Oufella, Hafid   +16 more
core   +2 more sources

Atherosclerosis [PDF]

open access: yesAnnals of the Rheumatic Diseases, 2002
Is atherosclerosis a cellular or humoral mediated autoimmune disease?
Y, Sherer, Y, Shoenfeld
openaire   +2 more sources

Cholesteryl ester transfer protein and high density lipoprotein responses to cholesterol feeding in men: relationship to apolipoprotein E genotype.

open access: yesJournal of Lipid Research, 1993
The apolipoprotein (apo) E isoform is an important determinant of the plasma lipoprotein distribution of apoE and of the metabolism of apoE-containing lipoproteins.
LJ Martin   +9 more
doaj   +1 more source

PRAS40 suppresses atherogenesis through inhibition of mTORC1-dependent pro-inflammatory signaling in endothelial cells [PDF]

open access: yes, 2019
Endothelial pro-inflammatory activation plays a pivotal role in atherosclerosis, and many pro-inflammatory and atherogenic signals converge upon mechanistic target of rapamycin (mTOR).
Althoff, Till F.   +14 more
core   +1 more source

Home - About - Disclaimer - Privacy