Results 1 to 10 of about 713,106 (307)

Exercise and Coronary Atherosclerosis: Observations, Explanations, Relevance, and Clinical Management. [PDF]

, 2020
Physical activity and exercise training are effective strategies for reducing the risk of cardiovascular events, but multiple studies have reported an increased prevalence of coronary atherosclerosis, usually measured as coronary artery calcification ...
Aengevaeren, VL, Eijsvogels, TMH, Mosterd, A, Möhlenkamp, S, Prakken, NHJ, Sharma, S, Thompson, PD, Velthuis, BK   +7 more
core   +3 more sources

Partial duplication of the EGF precursor homology domain of the LDL-receptor protein causing familial hypercholesterolemia (FH-Salerno).

Journal of Lipid Research, 1994
A novel mutation of low density lipoprotein (LDL)-receptor gene was found in an Italian family hypercholesterolemia (FH) patient during a screening of 300 FH patients.
S Bertolini, D D Patel, D A Coviello, N Lelli, M Ghisellini, R Tiozzo, P Masturzo, N Elicio, B L Knight, S Calandra   +9 more
doaj   +1 more source

Cholesteryl ester transfer protein and high density lipoprotein responses to cholesterol feeding in men: relationship to apolipoprotein E genotype.

Journal of Lipid Research, 1993
The apolipoprotein (apo) E isoform is an important determinant of the plasma lipoprotein distribution of apoE and of the metabolism of apoE-containing lipoproteins.
LJ Martin, PW Connelly, D Nancoo, N Wood, ZJ Zhang, G Maguire, E Quinet, AR Tall, YL Marcel, R McPherson   +9 more
doaj   +1 more source

MHC class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity [PDF]

, 2014
Background—Plasmacytoid dendritic cells (pDCs) bridge innate and adaptive immune responses and are important regulators of immuno-inflammatory diseases. However, their role in atherosclerosis remains elusive.
Ait-Oufella, Hafid, Baker, Lauren L., Cambrook, Helen, Finigan, Alison J., Grassia, Gianluca, Hansson, Göran K., Harrison, James E., Hugues, Stéphanie, Ludewig, Burkhard, Maffia, Pasquale, Mallat, Ziad, Masters, Leanne M., Murphy, Deirdre, Reith, Walter, Reizis, Boris, Sabir, Suleman, Sage, Andrew P.   +16 more
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Apolipoprotein E and Atherosclerosis: From Lipoprotein Metabolism to MicroRNA Control of Inflammation. [PDF]

, 2018
Apolipoprotein (apo) E stands out among plasma apolipoproteins through its unprecedented ability to protect against atherosclerosis. Although best recognized for its ability to mediate plasma lipoprotein clearance in the liver and protect against ...
Hasty, Hui, Hussain, Lin, Mahley, Pepe, Roselaar   +6 more
core   +2 more sources

PRAS40 suppresses atherogenesis through inhibition of mTORC1-dependent pro-inflammatory signaling in endothelial cells [PDF]

, 2019
Endothelial pro-inflammatory activation plays a pivotal role in atherosclerosis, and many pro-inflammatory and atherogenic signals converge upon mechanistic target of rapamycin (mTOR).
Althoff, Till F., Burghaus, Jana, Cao Ho, Thanh, Jürgensen, Lonny, Kamuf-Schenk, Verena, Katus, Hugo A., Kiper, Leon, Krull, Alexandros, Riechert, Eva, Schecker, Johannes, Stangl, Karl, Stangl, Verena, Völkers, Mirko, Wöltje, Kerstin, Zhang, Kevin Sun   +14 more
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Apolipoproteins C-III and E in apoB- and non-apoB-containing lipoproteins in two populations at contrasting risk for myocardial infarction: the ECTIM study. Etude Cas Témoins sur 'Infarctus du Myocarde

Journal of Lipid Research, 1996
Apolipoprotein (apo) C-III and apoE are components of two major classes of plasma lipoproteins, i.e., apoB- and non-apoB-containing lipoproteins. To analyze the relationship between the distribution of apoC-III and apoE among lipoproteins and coronary ...
G Luc, C Fievet, D Arveiler, A E Evans, J M Bard, F Cambien, J C Fruchart, P Ducimetiere   +7 more
doaj   +1 more source

Bcl-2 protein family: Implications in vascular apoptosis and atherosclerosis [PDF]

, 2006
Apoptosis has been recognized as a central component in the pathogenesis of atherosclerosis, in addition to the other human pathologies such as cancer and diabetes.
A Ashkenazi, A Bakhshi, A Basu, A Gross, A Letai, A Mandic, A Nechushtan, A Nechushtan, A Ruiz-Vela, A Saxena, A Schinzel, A Strasser, AE Rusinol, AJ Bruce-Keller, AP Gilmore, AS Belzacq, AZ Badrichani, B Antonsson, B Fadeel, B Hufnagel, C Adrain, C Borner, C Napoli, C Scaffidi, C Soldani, D de Moissac, D Decaudin, D Heiser, DE Wood, DG Kirsch, DJ Veis, DM Finucane, DW Dickson, E Oda, EA Slee, EH Cheng, EJ Ackermann, FA Sinicrope, G Basanez, G Molostvov, G van Loo, G van Loo, GD Norata, GJ Griffiths, GV Putcha, H He, H Kataoka, H Li, HH Kim, HS Lee, Huveyda Basaga, I Marzo, I Marzo, J Chen, J Han, J Liu, J Masuda, J Yang, J Yu, J Yu, J Zha, JC Reed, JL Bodmer, K Nakano, K Ochs, K Sakurai, K Wang, K Yamamoto, KM Hajra, KM Murphy, L He, M Aritomi, M del Mar Martinez-Senac, M Narita, M Nguyen, M Sata, M Sata, M Sattler, MB Bogdanov, MC Wei, MJ Pollman, MM Kockx, MR Bennett, MR Morissette, MR Sprick, MY Donath, N Donovan, N Mirkovic, N Motoyama, O Kutuk, O Meilhac, OW Rokhlin, Ozgur Kutuk, P Pauletto, PM Yao, Q Huang, R Rashmi, R Ross, R Ross, RA Gottlieb, RJ Alvarez, RM Kluck, S Conus, S Desagher, S Dramsi, S Grethe, S Krajewski, S Nouraini, S Ottilie, S Shimizu, S Takarada, S Vicca, S Vicca, SA Keogh, SA Memon, SC Ruffolo, SJ Korsmeyer, SJ Korsmeyer, SJ Neame, SL Schendel, SN Willis, SR Datta, SR Datta, SW Muchmore, SY Hsu, T Ito, T Lee, T Shibue, TD Littlewood, TS Soderstrom, UK Messmer, V Mikhailov, V Mikhailov, V Petronilli, V Petronilli, W Zhang, X Cao, XM Sun, Y Deng, Y Gazitt, Y Konishi, Y Liang, Y Michowitz   +142 more
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2016 ESC/EAS GUIDELINES FOR THE MANAGEMENT OF DYSLIPIDAEMIAS

Российский кардиологический журнал, 2017
The Task Force for the Management of Dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS)Developed with the special contribution of the European Assocciation for Cardiovascular Prevention & ...
Alberico L. Catapano, Ian Graham, Guy De Backer, Olov Wiklund, John M. Chapman, Heinz Drexel, Arno V. Hoes, Catriona S. Jennings, Ulf Landmesser, Terje R. Pedersen, Željko Reiner, Gabriele Riccardi, Marja-Riitta Taskinen, Lale Tokgozoglu, W. M. Monique Verschuren, Charalambos Vlachopoulos, David A. Wood, Jose Luis Zamorano, Marie-Therese Cooney   +18 more
doaj   +1 more source

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases. [PDF]

, 2014
Low-grade systemic inflammation is often associated with metabolic syndrome, which plays a critical role in the development of the obesity-associated inflammatory diseases, including insulin resistance and atherosclerosis.
DeFranco, Anthony L, Dicorleto, Paul E, Febbraio, Maria, Fox, Paul L, Harding, Clifford V, Hazen, Stanley L, Hise, Amy G, Hu, Bingqing, Li, Xiaoxia, Morton, Richard E, Nagy, Laura E, Ransohoff, Richard M, Roychowdhury, Sanjoy, Schmitt, David, Smith, Jonathan D, Wang, Jian-an, Xiao, Nengming, Yu, Minjia, Zhao, Junjie, Zhou, Hao   +19 more
core   +2 more sources