Results 51 to 60 of about 706,977 (192)

Recent advances in the treatment of venous thromboembolism in the era of the direct oral anticoagulants [version 1; referees: 2 approved]

open access: yesF1000Research, 2017
The direct oral anticoagulants (DOACs) have now supplanted vitamin K antagonists (VKAs) for the treatment of venous thromboembolism (VTE). The DOACs include dabigatran, which inhibits thrombin, and rivaroxaban, apixaban, and edoxaban, which inhibit ...
Jeffrey I. Weitz   +2 more
doaj   +1 more source

Owning a Pet Is Associated with Changes in the Composition of Gut Microbiota and Could Influence the Risk of Metabolic Disorders in Humans

open access: yesAnimals, 2021
Pet ownership positively influences clinical outcomes in cardiovascular prevention. Additionally, cardiovascular disease (CVD) has been previously linked to microbiota dysbiosis.
Javier Arenas-Montes   +10 more
doaj   +1 more source

Is there a role for thoracic aortic calcium to fine-tune cardiovascular risk prediction? [PDF]

open access: yes, 2012
Screening asymptomatic subjects to streamline measures for the prevention of cardiovascular events remains a major challenge. The established primary prevention risk-scoring methods use equations derived from large prospective cohort studies, but further
Birgelen, C. von, Hartmann, M.
core   +3 more sources

Inflammation and Atherosclerosis [PDF]

open access: yesEuropean Journal of Vascular and Endovascular Surgery, 2006
The aim of this article is to discuss the role of inflammation in atherosclerosis.An initial chemical, mechanical or immunological insult induces endothelial dysfunction. This triggers a cascade of inflammatory reactions, in which monocytes, macrophages, T lymphocytes and vascular smooth muscle cells participate. Leukocyte adhesion molecules, cytokines,
Kaperonis, EA   +4 more
openaire   +3 more sources

Influence of dietary intervention on microvascular endothelial function in coronary patients and atherothrombotic risk of recurrence

open access: yesScientific Reports, 2021
Endothelial dysfunction is a key player in both the onset and development of atherosclerosis. No study has examined whether healthy dietary patterns can improve microvascular endothelial function in patients with coronary heart disease (CHD) in the long ...
Marta Millan-Orge   +11 more
doaj   +1 more source

Computational Modelling of Atherosclerosis

open access: yes, 2015
Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk from elevated ...
Baldrick, Francina R   +4 more
core   +1 more source

Carotid intima media thickness and low high-density lipoprotein (HDL) in South Asian immigrants: could dysfunctional HDL be the missing link? [PDF]

open access: yes, 2014
IntroductionSouth Asian immigrants (SAIs) in the US exhibit higher prevalence of coronary artery disease (CAD) and its risk factors compared with other ethnic populations.
Dodani, Sunita   +3 more
core   +2 more sources

Atherosclerosis

open access: yes, 2017
In this chapter, we discuss the manner through which the immune system regulates the cardiovascular system in health and disease. We define the cardiovascular system and elements of atherosclerotic disease, the main focus in this chapter. Herein we elaborate on the disease process that can result in myocardial infarction (heart attack), ischaemic ...
Rahman, MS, Woollard, K
openaire   +4 more sources

Atherosclerosis and Autoimmunity [PDF]

open access: yesMediators of Inflammation, 2018
Abstract Despite a decline in mortality rates in several countries, cardiovascular disease remains the leading cause of death responsible for approximately half of all deaths on the continent. Coronary artery disease and stroke are often the result of acute complications of atherosclerosis (AS) and atherothrombosis.
Francesca Romana Spinelli   +4 more
openaire   +3 more sources

Secretion of biologically active human proapolipoprotein A-I in a baculovirus-insect cell system: protection from degradation by protease inhibitors

open access: yesJournal of Lipid Research, 1995
Studies of the structure and function of apolipoprotein A-I (apoA-I) often require its purification by delipidation of high density lipoprotein isolated from large quantities of human plasma and separation of apoA-I from other plasma apolipoproteins.
L E Pyle   +4 more
doaj   +1 more source

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