Results 91 to 100 of about 55,917 (264)
, 2015 Furio Colivicchi,1 Catarina Sternhufvud,2 Sanjay K Gandhi3 1Cardiology Division, Emergency Department, San Filippo Neri Hospital, ASL Roma E, Rome, Italy; 2Global Payer Evidence and Pricing, AstraZeneca R&D, Mölndal, Sweden; 3Global Health ...
Colivicchi F, Sternhufvud C, Gandhi SK
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Toxicity of Atorvastatin on Isolated Brain Mitochondria: Neurotoxicity of Atorvastatin
, 2017 Background: Although the bio kinetics, metabolism and chemical toxicity of Atorvastatin are well known, until recently little attention was paid to the potential neurotoxic effect of Atorvastatin (Atv). Regarding the concrete evidences indicating Atv may
Sanaze Nasohi +4 more
core +1 more source
Internal Medicine Journal, EarlyView.Abstract Background Pharmacogenomic‐guided medication management optimises drug therapy to enhance patient outcomes. Despite clinical utility, implementation in Australia remains limited, partly due to the lack of clear and consistent guidance. Aim This study evaluated the presence and consistency of pharmacogenomic testing indication categories and ...
Ruby Soueid +4 more
wiley +1 more source
Immune Consequences of Metabolic Syndrome and Its Treatment: A Cytokine Perspective
Immunology, EarlyView.Peripheral blood mononuclear cells (PBMCs) from individuals with metabolic syndrome (MetS) who were not using glucose‐and/or lipid lowering medication (GLLM) exhibited a broader cytokine production profile after in vitro antigen‐specific stimulation than PBMCs from individuals with MetS using such medications and from healthy donors.
Isabela Ghetti Macedo Isaac +7 more
wiley +1 more source
Efficacy and Safety of Metformin and Atorvastatin Combination Therapy vs. Monotherapy with Either Drug in Type 2 Diabetes Mellitus and Dyslipidemia Patients (ATOMIC): Double-Blinded Randomized Controlled Trial [PDF]
Diabetes & Metabolism JournalBackground It is well known that a large number of patients with diabetes also have dyslipidemia, which significantly increases the risk of cardiovascular disease (CVD). This study aimed to evaluate the efficacy and safety of combination drugs consisting
Jie-Eun Lee +37 more
doaj +1 more source
Treatment strategies for interstitial granulomatous dermatitis: Systematic review and expert opinion
Journal of the European Academy of Dermatology and Venereology, EarlyView.Systematic review of 108 studies with a total of 182 patients with interstitial granulomatous dermatitis (IGD). IGD was frequently associated with systemic conditions or drug exposure. Management includes careful medication review and prompt withdrawal of potential triggers. Corticosteroids (systemic and topical) were commonly effective, while biologic
Francesco Bellinato +4 more
wiley +1 more source
Efficacy of atorvastatin on the prevention of contrast-induced acute kidney injury: a meta-analysis
, 2018 Ling-Yun Liu,1 Yang Liu,2 Mei-Yan Wu,2 Yan-Yan Sun,3 Fu-Zhe Ma2 1Department of Andrology, 2Department of Nephrology, the First Hospital of Jilin University, 3Department of Nephrology, the Fourth Hospital of Jilin University, Changchun, China Background:
Liu Y, Wu M, Liu L, Sun Y, Ma F
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Hypocholesterolemia in liver and cardiovascular disease: Friend or foe?
Journal of Internal Medicine, EarlyView.Abstract Hypocholesterolemia is perceived as benign given its association with lower cardiovascular risk. However, genetic and epidemiological evidence indicates that persistently low levels of low‐density lipoprotein cholesterol (LDL‐C) and apolipoprotein B (ApoB) arise from distinct biological mechanisms with different hepatic implications ...
Valentina Flagiello +3 more
wiley +1 more source
In Vitro Blood-Brain-Barrier Permeability and Cytotoxicity of Atorvastatin-Loaded Nanoformulation Against Glioblastoma in 2D and 3D Models [PDF]
, 2019 Inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase of the family of statins have been suggested as therapeutic options in various tumors.
Michael M, Lübtow +14 more
core +2 more sources
Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications
Journal of Periodontal Research, EarlyView.Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu +4 more
wiley +1 more source