Results 181 to 190 of about 55,917 (264)

Oxysterols in Cancer: From Biosynthesis and Pathophysiology to Targeted Therapeutics

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Mechanisms by which oxysterol targeting may enhance immunotherapy efficacy. This figure illustrates potential metabolic interventions that may improve antitumor immunity by modulating oxysterol related pathways. CH25H modulation may reduce 25‐HC accumulation, promote the conversion of cold tumors into hot tumors, and increase T cell infiltration and PD‐
Haili Shang, Yongsheng Li
wiley   +1 more source

Impact of a pharmacist adherence intervention on medication beliefs and drug-related problems in coronary patients - a process evaluation of the MIMeRiC trial. [PDF]

BMC Health Serv Res
Östbring MJ, Al Musawi A, Eriksson T, Hellström L.   +3 more
europepmc   +1 more source

A Catalogue of Dispensation Lengths for Building Treatment Episodes—Application of the Waiting Time Distribution to All Commonly Prescribed Drugs in Denmark

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 9, September 2026.
ABSTRACT Background In pharmacoepidemiologic research, correct assignment of the length of single dispensation is critical to build treatment episodes. The parametric reverse waiting time distribution (rWTD) is a particularly attractive data‐driven method to estimate dispensation lengths.
Mette Reilev, Lotte Rasmussen, Jonas Kanstrup Olsen, Martin Thomsen Ernst, Saad Hanif Abbasi, Rikke Wesselhoeft, Mette Bliddal, Jesper Hallas, Henrik Støvring   +8 more
wiley   +1 more source

A cofactor‐promiscuous HMGR from the Lyme disease pathogen illuminates diversity in bacterial isoprenoid biosynthesis

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The Lyme disease pathogen Borrelia burgdorferi contains a highly reduced genome lacking many primary metabolic pathways. However, B. burgdorferi retains the mevalonate pathway that synthesizes isopentenyl pyrophosphate (IPP), the precursor to the peptidoglycan carrier lipid.
Isaac A. Paddy, Joshua McCausland, Madelyn Frazier, Poulami Chatterjee, Mekedlawit Setegne, Oliv Eidam, Christine Jacobs‐Wagner, Laura M. K. Dassama   +7 more
wiley   +1 more source

Sex-Dependent Vascular Responses to Atorvastatin Across Multiple Arterial Beds in a Mouse Model of Marfan Syndrome. [PDF]

Cells
Hunt P, Huynh K, Gusek B, Stimpson A, Rahimian R, Esfandiarei M.   +5 more
europepmc   +1 more source

BASTA trial: protocol for a randomised, double-blind, placebo-controlled, crossover trial investigating the effects of atorvastatin on bile acid diarrhoea. [PDF]

BMJ Open
Lynggaard MB, Olsen SS, Forman JL, Kårhus ML, Gluud LL, Lund AB, Ellegaard AM.   +6 more
europepmc   +1 more source

Multicomponent Analysis of Antihyperlipidemic Drugs: Integrating Analytical Quality by Design and Multi‐Metric Green Liquid Chromatography

SEPARATION SCIENCE PLUS, Volume 9, Issue 9, September 2026.
Robust HPLC method quantifies four antihyperlipidemic drugs. Central composite design optimized the analytical conditions. Achieved complete isocratic separation in under 10 min. Multiple green metrics confirmed excellent environmental sustainability. Validated method successfully analyzed commercial binary formulations.
Venkatesh Bukkapatnam, Raja Sundararajan
wiley   +1 more source

Novel reference gene microseminoprotein‐beta based prostate cancer antigen 3 urine test: Enhanced diagnostic performance for prostate cancer and feasibility of non‐digital rectal examination urine sampling

UroPrecision, Volume 4, Issue 3, Page 154-163, September 2026.
Abstract Background The diagnosis of prostate cancer (PCa) is limited by low specificity and invasiveness. This study aims to establish a highly accurate, noninvasive reverse transcription‐quantitative polymerase chain reaction (RT‐qPCR)‐based urinary prostate cancer antigen 3 (PCA3) assay system and explore the feasibility of using first‐morning urine
Jianglei Xu, Lu Yang, Cong Shi, Yiwei Jiang, Jing Chen, Xiaoxiao Sun, Xuejuan Gao, Xian Wang, Jianzhong Jiang, Xiuzhi Duan, Xuchu Wang, Yiyi Xie, Zhixian Yu, Zhihua Tao, Xiaobing Dou, Chunyu Jin   +15 more
wiley   +1 more source

The Influence of Statin Therapy on Markers of Endothelial Dysfunction, Endocan and Endoglin, in Postmenopausal Women-A Prospective Study. [PDF]

Biomedicines
Šojat D, Pirić M, Lukić M, Horvat V, Šafer M, Feldi I, Bačun T, Kibel A.   +7 more
europepmc   +1 more source

Efficacy and Safety of Ultra‐Low Starting Dose Febuxostat Titration in Male Patients With Primary Gout

International Journal of Rheumatic Diseases, Volume 29, Issue 9, September 2026.
ABSTRACT Background Since gout is a common metabolic arthritis caused by urate crystal deposition, urate‐lowering therapy (ULT) is clearly indicated, but the initiation of ULT frequently causes paradoxical acute flares that in turn impair patient adherence.
Sun Huizhen, Li Yadi, Guo Lin, Sun Rui, Guo Xuemei, Li Ping   +5 more
wiley   +1 more source