Results 131 to 140 of about 105,814 (267)

Statin intensity and postoperative mortality following open repair of intact abdominal aortic aneurysm. [PDF]

, 2018
BackgroundThere is a lack of evidence for the association between intensive statin therapy and outcomes following vascular surgery. The aim of this study was to evaluate the association between perioperative statin intensity and in-hospital mortality ...
Alshaikh, HN, Bohsali, F, Gani, F, Malas, M, Nejim, B   +4 more
core  

A Statistical Model for Stroke Outcome Prediction and Treatment Planning

, 2016
Stroke is a major cause of mortality and long--term disability in the world. Predictive outcome models in stroke are valuable for personalized treatment, rehabilitation planning and in controlled clinical trials.
Bhattacharya, Sakyajit, Rajan, Vaibhav, Sarma, G R K, Sengupta, Abhishek   +3 more
core   +1 more source

Differential and Joint Effects of Metformin and Statins on Overall Survival of Elderly Patients with Pancreatic Adenocarcinoma: A Large Population-Based Study. [PDF]

, 2017
Background: Published evidence indicates that individual use of metformin and statin is associated with reduced cancer mortality. However, their differential and joint effects on pancreatic cancer survival are inconclusive.Methods: We identified a large ...
Demissie, Kitaw, E, Jian-Yu, Graber, Judith M., Lin, Yong, Lu, Shou-En, Lu-Yao, Grace, Petersen, Gloria M., Rotter, David, Tan, Xiang-Lin, Zhang, Lanjing   +9 more
core   +2 more sources

Cryptococcid Sweet Syndrome in the Setting of Hydralazine‐Induced ANCA Vasculitis: A Case Report

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Acute febrile neutrophilic dermatosis, also known as Sweet syndrome, is an inflammatory skin condition characterized by the rapid onset of painful, erythematous plaques or nodules with neutrophilic infiltrate on histology. Rarely, acellular bodies surrounded by vacuolated spaces have been noted within the neutrophilic infiltrate, mimicking ...
Jenna Vroman, Pelin Sagut, Kathryn Lynam, Amanda Ederle, Laura Winterfield   +4 more
wiley   +1 more source

Intensive versus standard dose statin therapy: the costs and benefits for patients with acute coronary syndrome [PDF]

Introduction: Recent NICE guidance in England and Wales states that statin therapy for secondary CVD should "usually be initiated with a drug with a low acquisition cost (taking into account required daily dose and product price per dose)".
Ara, R., Hall, A.S., Pandor, A., Ward, S.   +3 more
core   +3 more sources

Can analyses of electronic patient records be independently and externally validated? The effect of statins on the mortality of patients with ischaemic heart disease: a cohort study with nested case-control analysis [PDF]

, 2014
Objective To conduct a fully independent and external validation of a research study based on one electronic health record database, using a different electronic database sampling the same population.
Ashcroft, DM, Doran, T, Kontopantelis, E, Morris, R, Olier, I, Reeves, D, Ryan, R, Springate, DA   +7 more
core   +2 more sources

Long‐term disease control of disseminated superficial actinic porokeratosis (DSAP) with simvastatin 2%/ cholesterol 2% cream

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Introduction Disseminated superficial actinic porokeratosis (DSAP) is a rare keratinization disorder associated with an increased risk of cutaneous tumors. Objectives To develop a feasible and easy‐to‐apply treatment regimen for long‐time disease control of DSAP including prevention of new skin tumors. Patients and Methods 19 patients with DSAP
Berenice M. Lang, Gregor Ojak, Mandy Crummenauer, Joanna Wegner, Caroline Mann, Stephan Grabbe, Petra Staubach   +6 more
wiley   +1 more source

Atorvastatin induces bile acid-synthetic enzyme Cyp7a1 by suppressing FXR signaling in both liver and intestine in mice[S]

Journal of Lipid Research, 2014
Statins are effective cholesterol-lowering drugs to treat CVDs. Bile acids (BAs), the end products of cholesterol metabolism in the liver, are important nutrient and energy regulators.
Zidong Donna Fu, Julia Yue Cui, Curtis D. Klaassen   +2 more
doaj   +1 more source

Antifungal effect of Atorvastatin against Candida species in comparison to Fluconazole and Nystatin

Medicine and Pharmacy Reports, 2019
Background and aims Atorvastatin is a plasma cholesterol-lowering drug which applies antifungal effects by inhibiting the production of yeast cell wall ergostrol.
A. N. Esfahani, Zahra Golestannejad, F. Khozeimeh, P. Dehghan, Mehrnoosh Maheronnaghsh, Zahra Zarei   +5 more
semanticscholar   +1 more source

Providing holistic care for patients with metabolic dysfunction‐associated steatotic liver disease/metabolic dysfunction‐associated steatohepatitis: Key aspects of clinical assessment and how to develop individualised care plans for surveillance and interventions

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD), characterised by hepatic steatosis and metabolic dysfunction (i.e., obesity, type 2 diabetes, dyslipidaemia, and hypertension), is affecting over 30% of the adult population worldwide.
Lanlan Chen, Paul Horn, Frank Tacke
wiley   +1 more source