Results 71 to 80 of about 55,691 (247)
British Journal of Pharmacology, EarlyView.Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher +6 more
wiley +1 more source
, 2011 Expression of functionally active thrombomodulin (TM) on endothelial cells is critical for vascular thromboresistance . 3-Hydroxyl-3-methyl coenzyme A reductase inhibitors ( statins) can protect the vasculature from inflammation and atherosclerosis ...
林幸榮;謝芳瑜;陳永祥;林家齊;管奕奕;王淑慧;吳造中;簡雄飛;林豐彥;陳玉怜 +1 more
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Estudo do efeito da atorvastatina sobre alterações comportamentais e bioquímicas em camundongos infundidos com o peptídeo ß-amilóide (Aß1-40) [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.A doença de Alzheimer (DA) é uma enfermidade neurológica que afeta grande parte da população mundial.
Martins, Wagner Carbolin
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Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights
British Journal of Pharmacology, EarlyView.Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra +5 more
wiley +1 more source
Journal of Biomedical Science, 2009 Atorvastatin has been shown to reduce resistin expression in macrophages after pro-inflammatory stimulation. However, the mechanism of reducing resistin expression by atorvastatin is not known. Therefore, we sought to investigate the molecular mechanisms
Chua Su-Kiat +3 more
doaj +1 more source
Porównanie intensywnego i standardowego obniżania stężenia lipidów za pomocą atorwastatyny u chorych z dyslipidemią cukrzycową Badanie DALI - podwójnie ślepa, randomizowana próba kliniczna kontrolowana placebo, przeprowadzona u chorych na cukrzycę typu 2 i dyslipidemię cukrzycową [PDF]
, 2002 INTRODUCTION. In patients with type 2 diabetes, intensive glucose regulation, although effective for microangiopathy, has not been shown to have unambiguous preventive effects on the occurrence of cardiovascular disease.
Intervention, Diabetes Atorvastatin Lipid
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Effects of atorvastatin and simvastatin on atrial plateau currents
, 2007 Recent evidence has shown that the inhibitors of the 3-hydroxy-3-methylglutaryl coenzyme A reductase (statins) might exert antiarrhythmic effects both in experimental models and in humans.
Vaquero González, Luis Miguel +5 more
core +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest +3 more
wiley +1 more source
Dose-dependent effects of atorvastatin on myocardial infarction
, 2015 Olga Barbarash, Olga Gruzdeva, Evgenya Uchasova, Ekaterina Belik, Yulia Dyleva, Victoria KaretnikovaFederal State Budgetary Institution, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, the Russian Federation Background ...
Dyleva Y +5 more
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