Results 1 to 10 of about 1,508,022 (243)

Searching for alternative toxicology testing systems: The response of isolated mitochondria from Saccharomyces cerevisiae, potato tuber, and mouse liver to a toxic insult [PDF]

open access: yesTrends in Pharmaceutical Sciences, 2021
Mitochondria are cellular power plants known as essential organelles for energy (ATP) metabolism. However, today it is evident that various vital compounds are partially or exclusively synthesized in mitochondria. Moreover, this organelle plays a pivotal
Pouria Mobasher   +5 more
doaj   +1 more source

IGF-1 as a Potential Therapy for Spinocerebellar Ataxia Type 3

open access: yesBiomedicines, 2022
Although the effects of growth hormone (GH) therapy on spinocerebellar ataxia type 3 (SCA3) have been examined in transgenic SCA3 mice, it still poses a nonnegligible risk of cancer when used for a long term. This study investigated the efficacy of IGF-1,
Yong-Shiou Lin   +5 more
doaj   +1 more source

A pilot study: handgrip as a predictor in the disease progression of SCA3

open access: yesOrphanet Journal of Rare Diseases, 2023
Background Spinocerebellar ataxia type 3 (SCA3) is an inherited, autosomal, and rare neurodegenerative disease. Serum/plasma biomarkers or functional magnetic resonance imaging used to assess progression, except for neurological examinations, is either ...
Chungmin Chiu   +8 more
doaj   +1 more source

Making ATP [PDF]

open access: yesProceedings of the National Academy of Sciences, 2005
We present a mesoscopic model for ATP synthesis by F 1 F o ATPase. The model combines the existing experimental knowledge of the F 1 enzyme into a consistent mathematical model that illuminates how the stages in synthesis are related to the protein structure.
Jianhua, Xing   +2 more
openaire   +2 more sources

ATP‐induced ATP release from astrocytes [PDF]

open access: yesJournal of Neurochemistry, 2003
AbstractPropagation of interastrocyte Ca2+waves is mediated by diffusion of extracellular adenosine triphosphate (ATP), and may require regenerative release of ATP. The ability of ATP to initiate release of intracellular ATP was assessed by labeling adenine nucleotide pools in astrocyte cultures with14C‐adenine.
Christopher M, Anderson   +2 more
openaire   +2 more sources

Association of leukocyte mitochondrial DNA copy number with longitudinal C-reactive protein levels and survival in older adults: a cohort study

open access: yesImmunity & Ageing, 2022
Background Systemic chronic inflammation occurs with age. The association of the leukocyte mitochondrial DNA copy number, a measure of mitochondrial function in aging, with the temporal profile of serum high-sensitivity C-reactive protein and mortality ...
I-Chien Wu   +9 more
doaj   +1 more source

Optical ATP biosensor for extracellular ATP measurement [PDF]

open access: yesBiosensors and Bioelectronics, 2013
Extracellular Adenosine-5'-triphosphate (ATP) is an important multi-functional molecule which can mediate numerous physiological activities by activating purinergic P2 receptors. The objective of this study was to develop a novel optical ATP sensor for in-situ extracellular ATP measurement in biological tissues.
C, Wang, C-Y C, Huang, W-C, Lin
openaire   +2 more sources

Prospective validation of a novel triage system developed in a middle income country - AIIMS triage protocol

open access: yesJournal of Emergencies, Trauma and Shock, 2022
Introduction: Triage is a crucial process not only to identify sick patients and prioritize prompt management but also to foster efficient resource utilization.
Satish Kumar Singh   +9 more
doaj   +1 more source

Impact of sorbitol and l-carnitine on stimulating thyroid hormone, triiodothyronine and adenosine triphosphate level in broilers [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2023
In order to provide more significant physiological benefits for the poultry sector, our research sought to assess the effectiveness of the two metabolic products, Sorbitol and L-carnitine, for energy production.
Hiyam N. Maty
doaj   +1 more source

Translating the Medieval Icelandic Romance-Sagas [PDF]

open access: yes, 2014
This short note surveys recent work done on translating romances composed in medieval Iceland into English, focusing on translations produced at the University of Leeds.
Hall, ATP
core   +1 more source

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