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ATP-binding cassette (ABC) transporters in caprine preantral follicles: gene and protein expression
Cell and Tissue Research, 2018The multidrug resistance proteins ABCB1, ABCC2 and ABCG2 are an energy-dependent efflux pump that functions in systemic detoxification processes. Physiologically expressed in a variety of tissues, most abundantly in the liver and intestinal epithelia, placenta, blood-brain barrier and various stem cells, until now, these pumps were not identified in ...
Guerreiro, Denise Damasceno +10 more
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Fungal ATP-Binding Cassette (ABC) Transporters in Drug Resistance & Detoxification
Current Drug Targets, 2006Pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi. PDR shares several similarities with processes in bacteria and higher eukaryotes. In mammalian cells, multidrug resistance (MDR) develops from an initial single drug resistance, eventually leading to a broad cross-resistance to many structurally and functionally ...
György, Sipos, Karl, Kuchler
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ATP Binding Cassette (ABC) Transporters in Plant Development and Defense
ABC transporters (ATP-binding cassette transporters) are dynamic proteins found in both types of organisms, prokaryotes and eukaryotes. They play pivotal roles in the transportation of various substances along cellular membranes by utilizing ATPs. ABC transporters consist of four domains: two NBDs with highly conserved motifs and two TMDs.Sheeba Naaz +2 more
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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
Advanced Drug Delivery Reviews, 2012Johan W. Jonker, Alfred H Schinkel
exaly
ECF-Type ATP-Binding Cassette Transporters
Annual Review of Biochemistry, 2019Dirk Slotboom, Stephan Rempel
exaly
Structure and mechanism of ATP-binding cassette transporters
Philosophical Transactions of the Royal Society B: Biological Sciences, 2009Kaspar P Locher
exaly

