Results 41 to 50 of about 105,612 (201)
Nature Communications, 2022 In this work, the authors report an ATP-dependent phosphatidylserine floppase activity for the lysosomal ATP-binding cassette transporter TAPL.
Jun Gyou Park +8 more
doaj +1 more source
Plant hormone transporters: what we know and what we would like to know [PDF]
, 2017 Hormone transporters are crucial for plant hormone action, which is underlined by severe developmental and physiological impacts caused by their loss-of-function mutations.
Geisler, Markus +3 more
core +4 more sources
Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins
Nature Communications, 2021 In Gram-negative bacteria, lipoproteins are transported from the inner membrane (IM) to the outer membrane (OM) by the ATP-binding cassette (ABC) transporter LolCDE.
Stuti Sharma +7 more
doaj +1 more source
Midostaurin Reverses ABCB1-Mediated Multidrug Resistance, an in vitro Study
Frontiers in Oncology, 2019 Overexpression of ABC transporters in cancer cells is an underlying mechanism of multidrug resistance (MDR), leading to insensitive response to chemotherapeutic strategies. Thus, MDR is often results in treatment failure in the clinic.
Ning Ji +11 more
doaj +1 more source
Conformational motion of the ABC transporter MsbA induced by ATP hydrolysis.
PLoS Biology, 2007 We measured the amplitude of conformational motion in the ATP-binding cassette (ABC) transporter MsbA upon lipopolysaccharide (LPS) binding and following ATP turnover by pulse double electron-electron resonance and fluorescence homotransfer. The distance
Peter P Borbat +5 more
doaj +1 more source
Beni-Suef University Journal of Basic and Applied Sciences, 2019 Background ATP-binding cassette (ABC) transporters constitute one of the largest transporter protein families and play a role in diverse biological processes.
Indira Mikkili +4 more
doaj +1 more source
Molecular biology of amitraz resistance in cattle ticks of the genus Rhipicephalus [PDF]
, 2018 Amitraz is an important product for the control of cattle ticks around the world. In comparison with other products for the control of ticks, it is quite affordable and it has a rapid knock-down effect.
Berry, Christina M. +5 more
core +1 more source
Nature Communications, 2017 The vitamin B12 importer BtuCD-F is a type II ATP-binding cassette transporter. Here the authors use single-molecule fluorescence techniques to analyse ATP hydrolysis and substrate transport in individual BtuCD-F complexes embedded in liposomes, and ...
Joris M. H. Goudsmits +2 more
doaj +1 more source
A defective ABC transporter of the MRP family, responsible for the bean lpa1 mutation, affects the regulation of the phytic acid pathway, reduces seed myo-inositol and alters ABA sensitivity [PDF]
, 2011 We previously identified the lpa1 (low phytic acid) 280-10 line that carries a mutation conferring a 90% reduction in phytic acid (InsP6) content. In contrast to other lpa mutants, lpa1(280-10) does not display negative pleiotropic effects.
Bollini, Roberto +10 more
core +1 more source
Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1
Nature Communications, 2019 P-glycoprotein, an ATP-binding cassette (ABC) transporter, extrudes a large variety of xenobiotics from the cell which protects tissues from toxins.
Atsushi Kodan +6 more
doaj +1 more source