Results 41 to 50 of about 127,756 (395)

ABCG1 regulates mouse adipose tissue macrophage cholesterol levels and ratio of M1 to M2 cells in obesity and caloric restriction

open access: yesJournal of Lipid Research, 2015
In addition to triacylglycerols, adipocytes contain a large reserve of unesterified cholesterol. During adipocyte lipolysis and cell death seen during severe obesity and weight loss, free fatty acids and cholesterol become available for uptake and ...
Hao Wei   +4 more
doaj   +1 more source

Membrane Topology of the Lactococcal Bacteriocin ATP-binding Cassette Transporter Protein LcnC. Involvement of LcnC in Lactococcin A Maturation [PDF]

open access: yes, 1999
Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors with N-terminal leader peptides different from those present in preproteins exported by the general sec-dependent (type II) secretion pathway. These bacteriocins utilize
Axelsson   +60 more
core   +1 more source

The ATP Binding Cassette Transporter GeneCgCDR1 from Candida glabrata Is Involved in the Resistance of Clinical Isolates to Azole Antifungal Agents

open access: yesAntimicrobial Agents and Chemotherapy, 1999
The resistance mechanisms to azole antifungal agents were investigated in this study with two pairs of Candida glabrata clinical isolates recovered from two separate AIDS patients.
D. Sanglard   +4 more
semanticscholar   +1 more source

A-subclass ATP-binding cassette proteins in brain lipid homeostasis and neurodegeneration

open access: yesFrontiers in Psychiatry, 2012
The A-subclass of ATP-binding cassette (ABC) transporters comprises twelve structurally related members of the evolutionarily highly conserved superfamily of ABC transporters.
Armin P. Piehler   +3 more
doaj   +1 more source

Molecular biology of amitraz resistance in cattle ticks of the genus Rhipicephalus [PDF]

open access: yes, 2018
Amitraz is an important product for the control of cattle ticks around the world. In comparison with other products for the control of ticks, it is quite affordable and it has a rapid knock-down effect.
Berry, Christina M.   +5 more
core   +1 more source

Endoplasmic Reticulum Degradation of a Mutated ATP-binding Cassette Transporter Pdr5 Proceeds in a Concerted Action of Sec61 and the Proteasome*

open access: yesJournal of Biological Chemistry, 1998
Degradation of misfolded or tightly regulated proteins in the endoplasmic reticulum (ER) is performed by the cytosolic ubiquitin-proteasome system and therefore requires their prior transport back to the cytosol.
Richard K. Plemper   +3 more
semanticscholar   +1 more source

Peptides and ATP binding cassette peptide transporters [PDF]

open access: yesResearch in Microbiology, 2001
In this review our knowledge of ATP binding cassette (ABC) transporters specific for peptides is discussed. Besides serving a role in nutrition of the cell, the systems participate in various signaling processes that allow (micro)organisms to monitor the local environment. In bacteria, these include regulation of gene expression, competence development,
Detmers, F.J.M.   +2 more
openaire   +4 more sources

The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase

open access: yesNature Communications, 2022
In this work, the authors report an ATP-dependent phosphatidylserine floppase activity for the lysosomal ATP-binding cassette transporter TAPL.
Jun Gyou Park   +8 more
doaj   +1 more source

Plant hormone transporters: what we know and what we would like to know [PDF]

open access: yes, 2017
Hormone transporters are crucial for plant hormone action, which is underlined by severe developmental and physiological impacts caused by their loss-of-function mutations.
Geisler, Markus   +3 more
core   +4 more sources

Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins

open access: yesNature Communications, 2021
In Gram-negative bacteria, lipoproteins are transported from the inner membrane (IM) to the outer membrane (OM) by the ATP-binding cassette (ABC) transporter LolCDE.
Stuti Sharma   +7 more
doaj   +1 more source

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