Results 61 to 70 of about 2,025,163 (218)

Fingerprint of the mitochondrial ABC transporter Mdl1p from Saccharomyces cerevisiae [PDF]

, 2006
The multidrug resistance like protein 1 (Mdl1p) belongs to the class of ATP binding cassette (ABC) transporters which comprise a large family of membrane proteins utilising ATP hydrolysis to drive up-hill transport of a wide variety of solutes across ...
Hofacker, Matthias
core  

Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states.

, 2013
ABCB10 is one of the three ATP-binding cassette (ABC) transporters found in the inner membrane of mitochondria. In mammals ABCB10 is essential for erythropoiesis, and for protection of mitochondria against oxidative stress.
Gileadi, O., Li, Q., Yang, J., von Delft, F., Bullock, A.N., Barr, A. J., Ross, J., Sansom, M. S. P., Carpenter, E. P., Carpenter, E.P., Kim, J-I., Barr, A.J., Burgess-Brown, N.A., Shintre, C. A., Berridge, G., Marsden, B., Stansfeld, P.J., Sansom, M.S.P., Burgess-Brown, N. A., Bountra, C., Shrestha, L., Shintre, C.A., Goubin, S., Bullock, A. N., Pike, A. C. W., Kim, J.I., Pike, A.C.W., Edwards, A.M., Stansfeld, Phillip J., Edwards, A. M., Marsden, B. D.   +30 more
core   +1 more source

Type 2 diabetes is associated with reduced ATP-binding cassette transporter A1 gene expression, protein and function [PDF]

, 2011
Objective Increasing plasma glucose levels are associated with increasing risk of vascular disease. We tested the hypothesis that there is a glycaemia-mediated impairment of reverse cholesterol transport (RCT).
Paul Vijay, Christiane Albrecht, Desmond G Johnston, Newman Simon P., Ian F. Godsland, Simon P. Newman, Darrell Pavitt, Valabhji, Jonathan, Johnston, Desmond G, Albrecht, Christiane, Albrecht Christiane, Dipesh C Patel, Vijay Paul, Johnston Desmond G., Dipesh C. Patel, Simon P Newman, Pourreyron, Celine, Ian F Godsland, Jonathan Valabhji, Pavitt, Darrell, Pourreyron Celine, Patel, Dipesh C, Godsland, Ian F, Desmond G. Johnston, Pavitt Darrell, Celine Pourreyron, Newman, Simon P, Paul, Vijay, Valabhji Jonathan, Patel Dipesh C., Godsland Ian F., Patel, Dipesh C., Newman, Simon P., Godsland, Ian F., Johnston, Desmond G.   +34 more
core   +3 more sources

The implication of adipocyte ATP-binding cassette A1 and G1 transporters in metabolic complications of obesity. [PDF]

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2019
Obesity is characterised by imbalance in lipid metabolism manifested by high concentrations of circulating triacylglycerols and total cholesterol as well as low high-density lipoprotein (HDL) levels. Abnormalities related to these lipids lead to metabolic complications such as type 2 diabetes, arterial hypertension and cardiovascular disease.
Barbara Choromańska, Piotr Myśliwiec, Hady Razak Hady, Jacek Dadan, Hanna Myśliwiec, Tomasz Bonda, Adrian Chabowski, Agnieszka Mikłosz   +7 more
openaire   +2 more sources

Astrocyte‐Associated ABCA1/APOE Responses Accompany Hippocampal Lipid Remodeling and Ectopic Neuronal Accumulation During Epileptogenesis

Advanced Science, EarlyView.
During kainic acid‐induced epileptogenesis, astrocyte‐associated ATP‐binding cassette transporter A1 (ABCA1) and apolipoprotein E (APOE) responses accompany ectopic neurons and exploratory lipid alterations. In separate cohorts, bexarotene pretreatment and treatment on days 14–21 are associated with fewer ectopic hilar neurons and lower chronic seizure
Lu Chen, Xiao‐Rui Shi, Jia‐Yi Chen, Ying‐Ting Wang, Le Du, Yang Ni, Jun‐Min Chen, An‐Chen Guo, Qian Wu, Jian‐Ping Wu, Qun Wang   +10 more
wiley   +1 more source

Mechanistic insights into ATP hydrolysis by the ABC transporter TAP [PDF]

, 2004
The transporter associated with antigen processing (TAP) plays a pivotal role in the adaptive immune response against virus-infected or malignantly transformed cells.
Chen, Min
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Structure of WbdD : a bifunctional kinase and methyltransferase that regulates the chain length of the O antigen in Escherichia coli O9a [PDF]

, 2012
The Escherichia coli serotype O9a O-antigen polysaccharide (O-PS) is a model for glycan biosynthesis and export by the ATP-binding cassette transporter-dependent pathway.
James H. Naismith, Gregor Hagelueken, Bradley R. Clarke, Hagelueken, Gregor, Huang, Hexian, Chris Whitfield, Clarke, Bradley R., Whitfield, Chris, Tomas Lebl, Lebl, Tomas, Naismith, James H., Hexian Huang, Lebl, Tomas; id_orcid   +12 more
core   +1 more source

ATP-Binding cassette transporter A1 is involved in hepatic α-tocopherol secretion

The Journal of Nutritional Biochemistry, 2010
Vitamin E (alpha-tocopherol) is an essential fat-soluble nutrient with antioxidant properties. alpha-Tocopherol transfer protein (alpha-TTP), the product of the gene responsible for familial isolated vitamin E deficiency, plays an important role in maintaining the plasma alpha-tocopherol level by mediating the secretion of alpha-tocopherol by the liver.
Mototada, Shichiri, Yasukazu, Takanezawa, Daisy E, Rotzoll, Yasukazu, Yoshida, Tomokuni, Kokubu, Kazumitsu, Ueda, Hiroshi, Tamai, Hiroyuki, Arai   +7 more
openaire   +2 more sources

The Interplay Between Molybdopterin Synthase and Metal Metabolism Contributes to Pathogenicity in Acinetobacter baumannii

Advanced Science, EarlyView.
Pathogenic Acinetobacter baumannii scavenges metal ions as nutritional elements to survive within the host. This study demonstrates that molybdopterin synthase is essential for pathogenesis and full virulence during infection. Molybdopterin synthase subunit MoaE constitutes an intrinsically disordered C‐terminal histidine rich tail, which mediates ...
Min Jiao, Wenbo He, Zhenlin Ouyang, Ruochen Wang, Jiaxin Zhang, Xin Liu, Yiting Jing, Qinyue Yu, Xiaoyu He, Qian Qin, Litao Guo, Peter M. Hwang, Fang Zheng, Yurong Wen   +13 more
wiley   +1 more source

Trimethylamine-N-Oxide Treatment Induces Changes in the ATP-Binding Cassette Transporter A1 and Scavenger Receptor A1 in Murine Macrophage J774A.1 cells [PDF]

, 2015
BACKGROUND: Recently, trimethylamine N-oxide was introduced as a risk factor for atherosclerosis in terms of helping foam cell formation and worsening atherosclerosis complications.
Najar, AG, Yaghoobi, MM, Vahabzadeh, Z, Mohammadi, A, Jahani, Y   +4 more
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