Results 141 to 150 of about 45,380 (194)

The exquisite link between potassium homeostasis regulation and cardiovascular health: exploration and analysis. [PDF]

Front Physiol
Wang C, Huang X, Zhang Z, Lin D, Huang S.   +4 more
europepmc   +1 more source

Pharmaceutical agents targeting K_ATP channel modulate sweet taste sensitivity in mice. [PDF]

J Physiol Sci
Sawai C, Wang K, Horie K, Mitoh Y, Ueda H, Kamioka H, Yoshida R.   +6 more
europepmc   +1 more source

Effects of inflamed status on functional and molecular vascular reactivity

, 2007
Sorrentino, Rosalinda
core  

Some of the next articles are maybe not open access.

Related searches:

ATP-Sensitive Potassium Channels: A Review of their Cardioprotective Pharmacology

Journal of Molecular and Cellular Cardiology, 2000
ATP-sensitive potassium channels (K(ATP)) have been thought to be a mediator of cardioprotection for the last ten years. Significant progress has been made in learning the pharmacology of this channel as well as its molecular regulation with regard to cardioprotection.
Gary J Grover, Keith D Garlid
exaly   +3 more sources

Role of ATP-sensitive potassium channels in the basilar artery

American Journal of Physiology-Heart and Circulatory Physiology, 1993
This study examined the hypothesis that activation of ATP-sensitive potassium channels produces vasodilation and contributes to dilator responses of the basilar artery to acetylcholine in vivo. Diameter of the basilar artery (baseline diam = 245 +/- 14 microns, means +/- SE) was measured through a cranial window in anesthetized rats. RP52891 (1 microM)
F M, Faraci, D D, Heistad
openaire   +3 more sources

Mitochondrial ATP-sensitive potassium channels in surgical cardioprotection

Archives of Biochemistry and Biophysics, 2003
ATP-sensitive potassium channels allow for the coupling of membrane potential to cellular metabolic status. Two K(ATP) channel subtypes coexist in the myocardium with one subtype located in the sarcolemma membrane and the other in the inner membrane of the mitochondria. The ATP-sensitive potassium channels can be pharmacologically modulated by a family
James D Mccully, Sidney Levitsky
exaly   +3 more sources

Regulation of cholecystokinin secretion by ATP-sensitive potassium channels

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1994
The relationship of potassium channel activity to the secretion of cholecystokinin (CCK) was evaluated in STC-1 cells, an intestinal CCK-secreting cell line. Patch-clamp and 86Rb efflux studies showed that an ATP-sensitive potassium channel was endogenously expressed in STC-1 cells.
A W, Mangel, V, Prpic, N D, Snow, S, Basavappa, L J, Hurst, A I, Sharara, R A, Liddle   +6 more
openaire   +3 more sources

ATP‐Sensitive Potassium Channels and Their Physiological and Pathophysiological Roles [PDF]

Comprehensive Physiology, 2018
ABSTRACT ATP sensitive potassium channels (K ATP ) are so named because they open as cellular ATP levels fall. This leads to membrane hyperpolarization and thus links cellular metabolism to membrane excitability.
Tinker, A, Aziz, Q, Li, Y, Specterman, M
openaire   +4 more sources

The Pharmacology of ATP-Sensitive Potassium Channels

Annual Review of Pharmacology and Toxicology, 1993
A potassium (K) channel that was inhibited by physiological (f1M) concen­ trations of intracellular ATP ([ATP]i) and that opened as [ATP]i decreased was first described in the heart ( l). Subsequently, similar K -channels all with unitary conductances in the range of 40-80 pS (measured under symmetrical high K+ conditions) were also found to exist in ...
G, Edwards, A H, Weston
openaire   +3 more sources

ATP-Sensitive Potassium Channels

Current Pharmaceutical Design, 2005
ATP-sensitive potassium (K(ATP)) channels link membrane excitability to metabolism. They are regulated by intracellular nucleotides and by other factors including membrane phospholipids, protein kinases and phosphatases. K(ATP) channels comprise octamers of four Kir6 pore-forming subunits associated with four sulphonylurea receptor subunits.
Rodrigo, GC, Standen, NB
openaire   +3 more sources