Results 21 to 30 of about 1,031,420 (245)

ATP regulation in bioproduction [PDF]

open access: yesMicrobial Cell Factories, 2015
Adenosine-5'-triphosphate (ATP) is consumed as a biological energy source by many intracellular reactions. Thus, the intracellular ATP supply is required to maintain cellular homeostasis. The dependence on the intracellular ATP supply is a critical factor in bioproduction by cell factories.
Akihiko Kondo, Kiyotaka Y. Hara
openaire   +3 more sources

ATP transporters in the joints [PDF]

open access: yesPurinergic Signalling, 2021
AbstractExtracellular adenosine triphosphate (ATP) plays a central role in a wide variety of joint diseases. ATP is generated intracellularly, and the concentration of the extracellular ATP pool is determined by the regulation of its transport out of the cell.
Gabriel Herrero-Beaumont   +5 more
openaire   +3 more sources

Comportamento do sistema de aterramento de LDs 69 kV com estruturas de concreto sob descargas atmosféricas

open access: yesRevista Principia, 2013
Este trabalho analisa o comportamento do sistema de aterramento de Linhas de Distribuição de 69kV com estruturas de concreto dotadas de cabo para-raios quando submetidas a descargas atmosféricas. Neste estudo, foram modelados com a utilização do software
Antonio dos Santos Dália   +2 more
doaj   +1 more source

Methylene Blue Treatment Enhances Mitochondrial Function and Locomotor Activity in a C57BL/6 Mouse Model of Multiple Sclerosis [PDF]

open access: yesTrends in Pharmaceutical Sciences, 2020
Multiple sclerosis (MS) is a neurodegenerative disease. Although multiple factors are involved in the pathogenesis of MS, there are several lines of evidence that oxidative stress and mitochondrial dysfunction are involved in neuronal demyelination and ...
Mohammad Mehdi Ommati   +5 more
doaj   +1 more source

Extracellular ATP: A Feasible Target for Cancer Therapy

open access: yesCells, 2020
Adenosine triphosphate (ATP) is one of the main biochemical components of the tumor microenvironment (TME), where it can promote tumor progression or tumor suppression depending on its concentration and on the specific ecto-nucleotidases and receptors ...
Valentina Vultaggio-Poma   +2 more
semanticscholar   +1 more source

Colostrum fails to prevent bovine/camelid neonatal neutrophil damage from AFB1

open access: yesJournal of Immunotoxicology, 2020
Exposure to environmental toxicants that affect the immune system and overall health of many mammals is mostly unavoidable. One of the more common substances is the mycotoxins, especially carcinogenic aflatoxin (AF)B1 which also causes immune suppression/
Sajad Najafi   +4 more
doaj   +1 more source

A Systematic Review of the Expression, Signalling and Function of P2 Receptors in Primary Bone Cancer

open access: yesFrontiers in Bioscience-Landmark, 2022
Primary bone cancers are rare malignant diseases with significant morbidity and mortality. The treatment regimen relies on a combination of surgery (often involving amputation), chemotherapy and radiotherapy with outcomes dependent on localization of the
Luke Tattersall   +5 more
doaj   +1 more source

Dynamic Sensitivity of ATP-sensitive K+Channels to ATP [PDF]

open access: yesJournal of Biological Chemistry, 2001
ATP and MgADP regulate K(ATP) channel activity and hence potentially couple cellular metabolism to membrane electrical activity in various cell types. Using recombinant K(ATP) channels that lack sensitivity to MgADP, expressed in COSm6 cells, we demonstrate that similar on-cell activity can be observed with widely varying apparent submembrane [ATP ...
Loussouarn, G   +4 more
openaire   +4 more sources

Effects of stunning methods on pre rigor changes in rainbow trout (Oncorhynchus mykiss) reared at two different temperatures

open access: yesItalian Journal of Animal Science, 2020
The effects of two stunning methods (carbon monoxide asphyxia, CO, and electroshock, E) on blood plasma parameters, rigor index, fillet pH and shape changes, ATP breakdown and Adenylate Energy Charge (AEC) in muscle immediately post mortem were ...
Anna Concollato   +6 more
doaj   +1 more source

α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease

open access: yesNature Communications, 2018
Protein aggregation causes α-synuclein to switch from its physiological role to a pathological toxic gain of function. Under physiological conditions, monomeric α-synuclein improves ATP synthase efficiency.
M. H. Ludtmann   +22 more
semanticscholar   +1 more source

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