Results 31 to 40 of about 1,728,775 (305)
Methylene Blue Treatment Enhances Mitochondrial Function and Locomotor Activity in a C57BL/6 Mouse Model of Multiple Sclerosis [PDF]
Trends in Pharmaceutical Sciences, 2020 Multiple sclerosis (MS) is a neurodegenerative disease. Although multiple factors are involved in the pathogenesis of MS, there are several lines of evidence that oxidative stress and mitochondrial dysfunction are involved in neuronal demyelination and ...
Mohammad Mehdi Ommati +5 more
doaj +1 more source
ATP regulation in bioproduction [PDF]
Microbial Cell Factories, 2015 Adenosine-5'-triphosphate (ATP) is consumed as a biological energy source by many intracellular reactions. Thus, the intracellular ATP supply is required to maintain cellular homeostasis. The dependence on the intracellular ATP supply is a critical factor in bioproduction by cell factories.
Akihiko Kondo, Kiyotaka Y. Hara
openaire +3 more sources
Colostrum fails to prevent bovine/camelid neonatal neutrophil damage from AFB1
Journal of Immunotoxicology, 2020 Exposure to environmental toxicants that affect the immune system and overall health of many mammals is mostly unavoidable. One of the more common substances is the mycotoxins, especially carcinogenic aflatoxin (AF)B1 which also causes immune suppression/
Sajad Najafi +4 more
doaj +1 more source
Frontiers in Bioscience-Landmark, 2022 Primary bone cancers are rare malignant diseases with significant morbidity and mortality. The treatment regimen relies on a combination of surgery (often involving amputation), chemotherapy and radiotherapy with outcomes dependent on localization of the
Luke Tattersall +5 more
doaj +1 more source
Nature Communications, 2018 Protein aggregation causes α-synuclein to switch from its physiological role to a pathological toxic gain of function. Under physiological conditions, monomeric α-synuclein improves ATP synthase efficiency.
M. H. Ludtmann +22 more
semanticscholar +1 more source
Dynamic Sensitivity of ATP-sensitive K+Channels to ATP [PDF]
Journal of Biological Chemistry, 2001 ATP and MgADP regulate K(ATP) channel activity and hence potentially couple cellular metabolism to membrane electrical activity in various cell types. Using recombinant K(ATP) channels that lack sensitivity to MgADP, expressed in COSm6 cells, we demonstrate that similar on-cell activity can be observed with widely varying apparent submembrane [ATP ...
Loussouarn, G +4 more
openaire +4 more sources
Italian Journal of Animal Science, 2020 The effects of two stunning methods (carbon monoxide asphyxia, CO, and electroshock, E) on blood plasma parameters, rigor index, fillet pH and shape changes, ATP breakdown and Adenylate Energy Charge (AEC) in muscle immediately post mortem were ...
Anna Concollato +6 more
doaj +1 more source
A Soluble Mitochondrial ATP Synthetase Complex Catalyzing ATP-Phosphate and ATP-ADP Exchange [PDF]
Proceedings of the National Academy of Sciences, 1971 The highly purified soluble ATP synthetase complex from mitochondria, containing energy-transfer Factor A (the terminal ADP phosphorylation enzyme of oxidative phosphorylation) and Factor D, catalyzes ATP-P i and ATP-ADP exchange reactions.
Jenn C. Chen +4 more
openaire +3 more sources
Purinergic receptor mediated calcium signalling in urothelial cells [PDF]
, 2019 Non-neuronal ATP released from the urothelium in response to bladder stretch is a key modulator of bladder mechanosensation. Whilst non-neuronal ATP acts on the underlying bladder afferent nerves to facilitate sensation, there is also the potential for ...
Brierley, Stuart M +4 more
core +3 more sources
Immunity & Ageing, 2022 Background Systemic chronic inflammation occurs with age. The association of the leukocyte mitochondrial DNA copy number, a measure of mitochondrial function in aging, with the temporal profile of serum high-sensitivity C-reactive protein and mortality ...
I-Chien Wu +9 more
doaj +1 more source