Results 61 to 70 of about 2,375 (156)

Blocking Sodium-Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice [PDF]

, 2020
Active secretion of bile salts into the canalicular lumen drives bile formation and promotes biliary cholesterol and phospholipid output. Disrupting hepatic bile salt uptake, by inhibition of sodium-taurocholate cotransporting polypetide (NTCP; Slc10a1 ...
Donkers, Joanne M, Duijst, Suzanne, Groen, Albert K, Havinga, Rick, Kuiper, Johan, Kuipers, Folkert, Oude Elferink, Ronald P J, Paulusma, Coen C, Roscam Abbing, Reinout L P, Slijepcevic, Davor, van de Graaf, Stan F J   +10 more
core   +1 more source

Identification of genes expressed during the compatible interaction of grapevine with Plasmopara viticola through suppression subtractive hybridization (SSH) [PDF]

, 2018
Grapevine (Vitis vinifera) is the most widely cultivated and economically important fruit crop, but is susceptible to a large number of diseases. Downy mildew, caused by the obligate biotrophic oomycete pathogen Plasmopara viticola, is a common disease ...
Berger, Dave, Legay, Guillaume, Marouf, Elaheh, Mauch-Mani, Brigitte, Neuhaus, Jean-Marc, Slaughter, Ana   +5 more
core  

高コレステロール血症と肥満の管理に役立つ新たな健康油の開発 [PDF]

, 2018
筑波大学University of Tsukuba博士（農学）Doctor of Philosophy in Agricultural Science2017この博士論文は、全文公表に適さないやむを得ない事由があり要約のみを公表していましたが、解消したため、令和２（2020）年6月３日に全文を公表しました ...
193442, TAKESHITA, Masao, 竹下, 尚男
core   +2 more sources

Genetic variation in the ABCB1 gene may lead to mRNA level change: Application to gastric cancer cases

, 2016
Background: One of the major mechanisms for drug resistance is associated with altered anticancer drug transport, mediated by the human-adenosine triphosphate binding cassette (ABC) transporter superfamily proteins.
Alizadeh, S., Fakharai, H., Golalipour, M., Jahangirerad, A., Khandozi, S.R., Mansoori, M., Shahbazi, M.   +6 more
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Studies on PCSK9 in the regulation of cholesterol metabolism [PDF]

, 2011
Elevated levels of plasma cholesterol, mainly in low density lipoproteins (LDL), are a major risk factor for coronary heart disease. The level of plasma LDL cholesterol (LDL-C) is largely dependent on the number of hepatic LDL receptors (LDLRs ...
Persson, Lena
core   +1 more source

Heterozygous <i>ABCG5</i> Gene Deficiency and Risk of Coronary Artery Disease. [PDF]

Circ Genom Precis Med, 2020
Nomura A, Emdin CA, Won HH, Peloso GM, Natarajan P, Ardissino D, Danesh J, Schunkert H, Correa A, Bown MJ, Samani NJ, Erdmann J, McPherson R, Watkins H, Saleheen D, Elosua R, Kawashiri MA, Tada H, Gupta N, Shah SH, Rader DJ, Gabriel S, Khera AV, Kathiresan S.   +23 more
europepmc   +1 more source

Influence of gene-environment interaction on the gut microflora-mammalian contribution to metabolism and toxicity

, 2008
Gut microbial composition and activity exert a strong influence on the metabolic phenotype of the host, and variation in the metabolic phenotype is a major factor underlying inter-individual variation in drug responses.
Swann, Jonathan Richard, Swann, Jonathan Richard   +1 more
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Influência da farmacogenòmica na terapêutica antidislipidémica [PDF]

, 2010
Dissertação de mest., Ciências Farmacêuticas, Faculdade de Ciências e Tecnologia, Univ. do Algarve, 2010As doenças cardiovasculares apresentam-se como uma das principais causas de óbito na maioria das sociedades modernas actuais.
Rodrigues, Catarina Silvestre
core  

The role of sugar sensing and pathway selection on D-xylose utilization by Saccharomyces cerevisiae [PDF]

, 2020
Biorefineries have the potential to partially or entirely replace petrochemistry for the production of our daily bulk and fine chemicals. However, this replacement can only be sustainable and cost-effective if the raw material used is cheap, renewable ...
Tufvegren, Celina
core  

Transcriptional Regulation of Azole Antifungal Resistance in Candida albicans [PDF]

, 2008
Candida albicans is a pathogenic fungi found in the mucosa, gastrointestinal, and urogenital tracts of humans. Oropharyngeal candidiasis (OPC), an opportunistic mucosal infection caused by C.
Liu, Teresa T.
core   +1 more source