Results 221 to 230 of about 837,065 (393)

Tie2‐Dependent Mechanisms Influence Leptomeningeal Collateral Dynamics and Reperfusion Following Stroke

Advanced Science, EarlyView.
This work demonstrates that endothelial EphA4 limits Tie2 activation and curbs leptomeningeal collateral expansion after ischemic stroke. Pharmacological activation of Tie2 by an Ang‐1 mimetic or genetic loss of EphA4 stimulates collateral vessel growth, improves cerebral perfusion, and enhances neurological recovery.
Alexandra M. Kaloss, Caroline de Jager, Kennedie Lyles, Nathalie A. Groot, Jackie Zhu, Yu Lin, Michael Chen, Hehuang Xie, John B. Matson, Michelle H. Theus   +9 more
wiley   +1 more source

Bioenergetics of cancer cells: insights into the Warburg effect and regulation of ATP synthase. [PDF]

Mol Med
Del Dotto V, Grillini S, Righetti R, Grandi M, Giorgio V, Solaini G, Baracca A.   +6 more
europepmc   +1 more source

Electron microscopy of two‐dimensional crystals of mitochondrial ATP synthase [PDF]

, 1993
Gennady E. Dubachev, Alexander V. Lunev, Alexander N. Barnakov, Grigory I. Belogrudov, В.А. Гринкевич, В. В. Демин   +5 more
openalex   +1 more source

A Research Journey with ATP Synthase [PDF]

Journal of Biological Chemistry, 2002
openaire   +3 more sources

Tead1a Initiates Transcriptional Priming Through the TEAD1a/YAP‐Notch1‐Spi1/Cebpα Axis to Promote Neutrophil Fate

Advanced Science, EarlyView.
This study discovered that the protein TEAD1a is crucial for neutrophil development. In zebrafish models, disrupting TEAD1a or its interaction with partner protein YAP1 caused severe neutrophil deficiency. TEAD1a functions during the early HSC stage, activates Notch1 signaling in the GMP stage, and triggers Spi1 and Cebpα to drive neutrophil terminal ...
Wang Yiqin, Yang Ruimeng, Wang Peihong, Liu Xiaohui, Yuan Hao, Huang Hongli, Zhou Yongjian, Xie Baoshu   +7 more
wiley   +1 more source

Engineering of ATP synthase for enhancement of proton-to-ATP ratio. [PDF]

Nat Commun
Ueno H, Yasuda K, Hamaguchi-Suzuki N, Marui R, Adachi N, Senda T, Murata T, Noji H.   +7 more
europepmc   +1 more source

ATP synthesis by the F₁F_o ATP synthase of Escherichia coli is obligatorily dependent on the electric potential [PDF]

, 1998
Georg Kaim, Peter Dimroth
openalex   +1 more source

TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition

Advanced Science, EarlyView.
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang, Ende Wu, Weibin Liu, Ling Zeng, Neng Ling, Hongmei Wang, Zhixing Li, Shuang Yao, Tonghe Pan, Xuanwen Li, Yate Huang, Xiaojing Li, Yunhai Tu, Wentao Yan, Jianzhang Wu, Mao Ye, Wencan Wu   +16 more
wiley   +1 more source

Photochemical ring-opening in 20-chloro-chlorophylls [PDF]

, 1990
D Dörnemann, D Dörnemann, GAF Hendry, H Brockmann Jr., H Fischer, H Scheer, H. P. Isenring, J Fajer, J-H Fuhrhop, J-H Fuhrhop, M Kobayashi, M Senge, M Senge, MS Huster, O Shimomura, PH Hynninen, PM Champion, RB Woodward, RE Moore, SB Brown, Scheer, T Katoh, T Watanabe, W Rüdiger   +23 more
core   +1 more source

When opposites compensate: proton flux crosstalk between envelope antiporters and ATP synthase. [PDF]

Plant Physiol
Singh R.
europepmc   +1 more source